|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | I | L | L | F | G | K | T | G | Q | V | G | W | E | L | Q | R | A | L | A | P | L | G | N | L | I | A | F | D | V | H | S | T | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | C | G | D | F | S | N | P | E | G | V | A | E | T | V | R | S | I | R | P | D | I | I | V | N | A | A | A | H |
Query Conservation |   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
Template Sequence |   |
R | V | F | V | T | G | H | T | G | F | K | G | S | W | L | S | L | W | L | T | E | M | G | A | I | V | K | G | Y | A | L | D | A | P | T | V | P | S | L | F | E | I | V | R | L | N | D | L | M | E | S | H | I | G | D | I | R | D | F | E | K | L | R | S | S | I | A | E | F | K | P | E | I | V | F | H | M | A | A | Q |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S | S |
| S | S | S | S |
|  |  |  |  | T | T | G | G | G | T | S |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
13 | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . |
  |
  |   |
65 | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | V | D | K | A | E | S | E | P | E | F | A | Q | L | I | N | A | T | S | V | E | A | I | A | K | A | A | N | E | V | G | A | W | V | I | H | Y | S | T | D | Y | V | F | P | G | N | G | D | M | . |
. |
. |
P | W | L | E | T | D | A | T | A | P | L | N | V | Y | G | E | T | K | L | A | G | E | K | A | L | Q | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
P | L | V | R | L | S | Y | E | Q | P | I | K | T | Y | S | T | N | V | M | G | T | V | H | L | L | E | T | V | K | Q | V | G | N | I | K | A | V | V | N | I | T | S | D | K | C | Y | D | N | R | E | W | V | W | G | Y | R | E | N | E | P | M | G | G | Y | D | P | Y | S | N | S | K | G | C | A | E | L | V | A | S | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
| G | G | G | B |
|
|
|
| S | S | S |
| B |
| T | T | S |
| B |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
93 | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . |
  |
  |   |
142 | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
|
|
. | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
C | A | K | H | L | I | F | R | T | S | W | V | Y | A | G | K | G | N | N | . |
. |
. |
. |
F | A | K | T | M | L | R | L | A | K | E | R | E | E | L | A | V | I | N | D | Q | F | G | A | P | T | G | A | E | L | L | A | D | C | T | A | H | A | I | R | V | A | L |
Query Conservation |   |
  | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | R | N | S | F | F | N | P | A | N | Y | E | Q | H | G | V | G | L | A | S | V | R | A | G | N | V | I | G | G | G | D | W | A | K | D | R | L | I | P | D | I | L | R | S | F | E | N | N | Q | Q | V | I | I | R | N | P | Y | S | I | R | P | W | Q | H | V | L | E | P | L | S | G | Y | I | V | V | A | Q | R | L | Y |
Template Known Secondary structure |   |
 |  |  |  |  | S |
| G | G | G |  |  |  |  |
|
|  |  |  |  |  |  |  |
|  |  |  |
| T | T |
|
|
| T | T |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  | S |
| T | T |
| B |
|
|  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
173 | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
  |
  |   |
205 | . | . | |
|
|
. | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
Predicted Secondary structure |   |
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
| . |
Query SS confidence |   |
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
N | K | P | . |
. |
. |
D | V | A | G | L | Y | H | L | V | A | S | G | T | T | T | W | Y | D | Y | A | A | L | V | F | E | E | A | R | K | A | G | I | P | L | A | L | N | K | L | N | A | V | P | T | T | A | Y | P | T | P | A | R | R | P | H | N | S | R | L | N | T | E | K | F | Q | Q | N | F | A | L | V | L | P | . |
Query Conservation |   |
  |   |   | . | . | . |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|   | . |
Alig confidence |   |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |
Template Sequence |   |
T | E | G | A | K | F | S | E | G | W | N | F | G | P | R | D | E | D | A | K | T | V | E | F | I | V | D | K | M | V | T | L | W | G | D | D | A | S | W | L | L | D | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | E | A | H | Y | L | K | L | D | C | S | K | A | N | M | Q | L | G | W | H | P | R | W |
Template Known Secondary structure |   |
 |
|  |  |  |  |
| S |  |  |  |  |
|
|
| G | G | G |
|
| B |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| S | B |
|
| B |
|
|  |  |  |  |  |  | T |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
  |
  |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | W | Q | V | G | V | K | R | M | L | N | E | L | F | T |
Query Conservation |   |
  |   |   |
|   |
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |
|   |
|   |   |   |
Template Sequence |   |
G | L | T | E | T | L | S | R | I | V | K | W | H | K | A |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
323 | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . |
  |