|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | N | I | L | L | F | G | K | T | G | Q | V | G | W | E | L | Q | R | A | L | A | P | L | G | N | L | I | A | F | D | V | H | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | D | Y | C | G | D | F | S | N | P | E | G | V | A | E | T | V | R | S | I | R | P | D | I | I | V | N | A |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
X | H | I | A | I | I | G | A | A | G | X | V | G | R | K | L | T | Q | R | L | V | K | D | G | S | L | G | G | K | P | V | E | K | F | T | L | I | D | V | F | Q | P | E | A | P | A | G | F | S | G | A | V | D | A | R | A | A | D | L | S | A | P | G | E | A | E | K | L | V | E | A | R | P | D | V | I | F | H | L | A |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  | T | T |  |  |  |  |  |  |  |  |  |  | S | S |
|
|
|
|
| T | T |
|
| S |  |  |  |  |  |  |
|
| T | T | S | T | T |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
  |
  |   |
62 | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | |
|
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | H | T | A | V | D | K | A | E | S | E | P | E | F | A | Q | L | I | N | A | T | S | V | E | A | . |
. |
. |
. |
I | A | K | A | A | N | E | V | G | A | W | V | I | H | Y | S | T | D | Y | V | F | P | G | N | G | D | M | P | W | L | E | T | D | A | T | A | P | L | N | V | Y | G | E | T | K | L | A | G | E | K |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
Template Sequence |   |
A | I | V | S | G | E | A | E | L | D | F | D | K | G | Y | R | I | N | L | D | G | T | R | Y | L | F | D | A | I | R | I | A | N | G | K | D | G | Y | K | P | R | V | V | F | T | S | S | I | A | V | F | G | A | P | L | P | Y | P | I | P | D | E | F | H | T | T | P | L | T | S | Y | G | T | Q | K | A | I | C | E | L |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  | G | G | G |
|
| S | S |
|
| S | S | B |
| T | T |
|
|
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
  |
  |   |
138 | . | 140 | . | . | |
|
|
|
. | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | |
|
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  | . | . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | L | Q | E | Y | . |
. |
. |
. |
C | A | K | H | L | I | F | R | T | S | W | V | Y | A | G | . |
. |
. |
. |
. |
. |
K | G | N | N | F | A | K | T | M | L | R | L | A | K | E | R | E | E | L | A | V | I | . |
. |
N | D | Q | F | G | A | P | T | G | A | E | L | L | A | D | C | T | A | H | A | I | R | V | A | L | N |
Query Conservation |   |
  |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |
|   |   |   |
|   |   |   | . |   |   |
Template Sequence |   |
L | L | S | D | Y | S | R | R | G | F | F | D | G | I | G | I | R | L | P | T | I | C | I | R | P | G | K | P | N | A | A | A | S | G | F | F | S | N | I | L | R | E | P | L | V | G | Q | E | A | V | L | P | V | P | E | S | I | R | H | W | H | A | S | P | R | S | A | V | G | F | L | I | H | G | A | X | I | . |
D | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |
|  |  | T | T |
|
| S | S |
|
|
| S | G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
| S |
| T | T |
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | . |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
. | . |
  |
  |   |
206 | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | |
. | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Query Sequence |   |
K | P | D | V | A | G | L | Y | H | L | V | A | S | G | T | T | T | W | Y | D | Y | A | A | L | V | F | E | E | A | R | K | A | G | I | P | L | A | L | N | K | L | N | A | V | P | T | T | A | Y | P | T | P | A | R | R | P | H | N | S | R | L | N | T | E | K | F | Q | Q | N | F | A | L | V | L | P | . |
D | W | Q | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |
|   | . |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |
|   |   |
|   |   |   | . |
|
|   |   |
|   |   |   |   |   |
|
Template Sequence |   |
E | K | V | G | P | R | R | N | L | S | X | P | G | L | S | A | T | V | G | E | Q | I | E | A | L | R | K | V | A | G | E | K | A | V | A | L | I | R | R | E | P | N | E | X | I | X | R | X | C | E | G | W | A | P | . |
. |
. |
. |
. |
G | F | E | A | K | R | A | R | E | . |
L | G | F | T | A | E | S | S | F | E | E |
Template Known Secondary structure |   |
 |  |  |
| S |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  | T | T |  |  |  |
|
|
|  |  |  |  |  |  |  | T | T | S |
|
| . | . | . | . | . |
| B |
|
|  |  |  |  |  | . | T | T |
|
|
|
| S | S |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 310 | |
. | . | . | . | . | . | . | . | . | 320 | . |
  |
  |   |
285 | . | . | . | . | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | K | R | M | L | N | E | L | F | T |
Query Conservation |   |
  |
|   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
|   |   |
|
|   |
Template Sequence |   |
I | I | Q | V | H | I | E | D | E | L | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
  |   |
322 | . | . | . | . | . | . | . | 330 | . | . |
  |