|   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | G | G | A | Y | Y | V | Y | K | L | G | A | R | A | D | M | S | T | R | W | Y | L | D | G | D | K | S | F | G | F | A | L | G | A | V | K | I | K | P | S | E | N | S | L | L | K | L | G | R | F | G | T | D | Y | S | Y | G | S | L | P | Y | R | I | . |
. |
. |
. |
. |
. |
. |
. |
P | L | M | A | G | S | S | Q | R |
Query Conservation |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . |
|   |   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|
|
|   |   |   |   |
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | M | K | A | I | W | Q | L | E | Q | K | A | S | I | A | G | T | N | S | G | W | G | N | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | S | F | I | G | L | K | G | G | F | G | T | V | R | A | G | N | L | N | T | V | L | K | D | S | G | D | N | V | N | A | W | E | S | G | S | N | T | E |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |
|
| T | T | S |
|
|
|
| S | S |
| S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | S |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  | G | G | G | T |
|
|
|
|
|
| G | G | G | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
54 | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . |
  |
  |   |
150 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
|
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | T | V | S | E | G | A | L | G | Y | W | A | L | T | P | N | I | D | L | W | G | M | W | R | S | R | V | F | L | W | T | D | S | T | T | G | I | R | D | E | G | V | Y | N | S | Q | T | G | K | Y | D | K | H | R | A | R | S | F | L | A | A | S | W | H | D | D | T | S | R |
Query Conservation |   |
  |   | . | . | . | . | . | . | . | . | . |
|   |
|
|   |
|   |   |
|   |
|   |   |
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|   |   |   |
|
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
D | V | L | G | L | G | T | I | G | R | V | E | S | R | E | I | S | V | R | Y | D | S | P | V | F | A | G | F | S | G | S | V | Q | Y | V | P | R | D | N | A | N | D | V | D | K | Y | K | H | T | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | S | R | E | S | Y | H | A | G | L | K | Y | E | N | A | G | F | F |
Template Known Secondary structure |   |
T | T | T | S |
|  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |
|
|
| B | T | T |  |  |  |  |  |  |  |  |
|  |  |  |  |
| S | T | T | S | S | S | T | T | S | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
117 | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
  |
  |   |
221 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | S | L | G | A | S | V | Q | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | V | S | N | Q | I | Q | S | I | L | E | K | S | I | P | L | D | P | N | Y | T | L | K | G | E | L | L | G | F | Y | A | Q | L | E | G | L | S | R | N | T | S | Q | P | N | E | T | A | L | V | S |
Query Conservation |   |
  |   |   |   |   |   |   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | Q | Y | A | G | S | F | A | K | Y | A | D | L | N | T | D | A | E | R | V | A | V | N | T | A | N | A | H | P | V | K | D | Y | Q | V | H | R | V | V | A | G | Y | D | A | N | D | L | . |
Y | V | S | V | A | G | Q | Y | E | A | A | K | N | N | E | V | G | S | I | K | G | K | K | H | E | Q | T | Q | V | A | A | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
| B |
|
| T | T |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S | T | T | T | T |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
185 | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | |
. | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . |
  |
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | L | T | W | N | A | P | W | G | S | V | F | G | S | G | G | Y | L | R | H | A | M | N | G | A | V | V | D | T | D | I | G | Y | P | F | S | L | S | L | D | R | N | R | E | G | M | Q | S | W | Q | L | G | V | N | Y | R | L | T | P | Q | F | T | L | T | F | A | P | I | V | T | R | G | Y | E | S | S | K | R | D |
Query Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|
|
|   |   |   |   |
|
|
|   |
|
|   |   |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|
|
|   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |
Template Sequence |   |
A | A | Y | R | F | G | N | V | T | P | R | V | S | Y | A | H | G | F | K | A | K | V | N | G | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | D | A | N | Y | Q | Y | D | Q | V | I | V | G | A | D | Y | D | F | S | K | R | T | S | A | L | V | S | A | G | W | L | K | . |
. |
. |
Q | G | K | G | A |
Template Known Secondary structure |   |
 |  |  |
| B | T | T |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  | T | T |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |  |  |  |  |  |  |  |  |  |  |  | . | . | . |  | S | S | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | |
|
|
. | . | . | . | . |
  |
  |   |
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | R | I | E | G | T | G | I | L | G | G | M | N | Y | R | V |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
Template Sequence |   |
G | K | V | E | Q | T | A | S | M | V | G | L | R | H | K | F |
Template Known Secondary structure |   |
S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
326 | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |