Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP76425
DateThu Jan 5 12:22:58 GMT 2012
Unique Job IDbe9b8541b1e72781

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c2l9uA_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:receptor tyrosine-protein kinase erbb-3;
PDBTitle: spatial structure of dimeric erbb3 transmembrane domain
Confidence and coverage
Confidence: 4.8% Coverage: 11%
31 residues ( 11% of your sequence) have been modelled with 4.8% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30.........40.........50.........60
Sequence  MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIAIKGTIKQAVMLGLAAT
Secondary structure 













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Disorder  ???



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??
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   .........70.........80.........90.........100.........110.........120
Sequence  ISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIISTAFWMFWRTWRGERNWLENM
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   .........130.........140.........150.........160.........170.........180
Sequence  HGHDYEHHHHDHEHHHDHGHHHHHEHGEYQDAHARAHANDIKRRFDGREVTNWQILLFGL
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Disorder  ????????????????????????
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   .........190.........200.........210.........220.........230.........240
Sequence  TGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLALTLVTVGVGAAISVQQVAKRWS
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?
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   .........250.........260.........270....
Sequence  GFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR
Secondary structure 

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Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region
No hits with confidence > 5%



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
No hits with confidence > 5%

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0