|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | |
|
|
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | S | T | A | E | I | R | Q | A | F | L | D | F | F | H | S | K | . |
. |
. |
G | H | Q | V | V | A | S | S | S | L | V | P | H | N | D | P | T | L | L | F | T | N | A | G | M | N | Q | F | K | D | . |
V | F | L | G | L | D | K | R | N | Y | S | R | A | T | T | S | Q | R | C | V | R | A | G | G | K | H | N | D |
Query Conservation |   |
  |   |
|   |   |
|
|
|   |   |
|
|   |
|
|   |   |   | . | . | . |
|
|   |   |
|   |
|   |
|
|
|
|   |   |
|   |   |
|
|
|   |
|
|
|
|   |   |
|
|   | . |   |
|   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|
|   |
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
Template Conservation |   |
  |   |
|   |   |
|
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |
|   |
|
|
|
|   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|
|
|
|
|   | . | . | . | . |
|
|
Template Sequence |   |
K | Y | T | L | D | E | M | R | E | K | F | L | R | F | F | E | K | H | E | I | Y | P | H | G | R | V | K | R | Y | P | V | L | P | R | W | R | D | D | V | L | L | V | G | A | S | I | M | D | F | Q | P | W | V | I | S | G | E | A | D | P | P | A | N | P | L | V | I | S | Q | P | S | I | R | F | . |
. |
. |
. |
T | D |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | S |
|
|  |  |
|
|
|
|
| S | S |
| T | T |
| S | S |
| S | S |
|
| S | G | G | G | G | G | T | T | T | T | T | T | T | S | S |
|
| S | S | S | S |  |  |  |  |  |  |  |  |
| S | . | . | . | . | T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
|
|
130 | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | N | V | G | Y | T | A | R | H | H | T | F | F | E | M | L | G | N | F | S | F | G | D | . |
. |
. |
. |
. |
Y | F | K | H | D | A | I | Q | F | A | W | E | L | L | T | S | E | K | W | F | A | L | P | K | E | R | L | W | V | T | V | Y | E | S | D | D | E | A | Y | E | I | W | E | K | E | V | G | I | P | R | E |
Query Conservation |   |
|
|   |
|
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|
| . | . | . | . | . |
|
|
|   |
|
|
|   |   |
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|   |   |   |   |
|   |
|   |   |   |
|
|   |   |   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |
|
|   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |
|
|
|   |
|
| . | . |   |   |
|
|
|   |   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
I | D | N | V | G | I | T | G | R | H | F | T | I | F | E | M | M | A | H | H | A | F | N | Y | P | G | K | P | I | Y | W | M | D | E | T | V | E | L | A | F | E | F | F | T | . |
. |
K | E | L | K | M | K | P | E | D | I | T | F | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
G | G | G | T | T | T | S | S | S |
|
| S |  |  |  |  |  |  |  |  |  |  |  | B | T | T | B |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  | T | S |
|
|
| G | G | G |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | I | I | R | I | G | D | N | K | G | A | P | Y | A | S | D | N | F | W | Q | M | G | D | T | G | P | C | G | P | C | T | E | I | F | Y | D | H | G | D | H | I | W | G | G | P | P | G | S | P | E | E | D | G | D | R | Y | I | E | I | W | N | I | V | F | M | Q | F | N | R | Q | A | D | G | T | M | E | P | L | P | K |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|   |   |
| . | . |
|
|
|
|
|
|
|
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|
|
|
|
|
|
|
|
|
|   | . | . | . | . |   |   |   |   |
|
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | N | P | W | A | G | G | . |
. |
G | N | A | G | P | A | F | E | V | L | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | G | L | E | V | A | T | L | V | F | M | Q | Y | K | K | . |
. |
. |
. |
K | Y | I | P | M | E | T |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|  |  |
| S | . | . | S |  |  |  |
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
189 | 190 | . | . | . | . | . | |
|
. | . | . | . | 200 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
|
|
|
. | . | . | . | . | . | . |
  |
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
P | S | V | D | T | G | M | G | L | E | R | I | A | A | V | L | Q | H | V | N | S | N | Y | D | I | D | L | F | R | T | L | I | Q | A | V | A | K | V | T | G | A | T | D | L | S | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |
|
|
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |
|
|
|
|   |   |
|
|
|
|
|
|
|   | . |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
K | V | V | D | T | G | Y | G | L | E | R | L | V | W | M | S | Q | G | T | P | T | A | Y | D | A | V | L | G | . |
Y | V | V | E | P | L | K | K | M | A | G | I | E | K | I | D | E | K | I | L | M | E | N | S | R | L | A | G | M | F | D | I | E | D | L | G | D | L | R | Y | L | R | E | Q | V | A | K | R | V | G | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  |  | S |  | . |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | T | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
279 | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | S | L | R | V | I | A | D | H | I | R | S | C | A | F | L | I | A | D | G | V | M | P | S | N | E | N | R | G | Y | V | L | R | R | I | I | R | R | A | V | R | H | G | N | M | L | G | A | K | E | T | F | F | Y | K | L | V | G | P | L | I | D | V | M | G | S | A | G |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . |   |
|   |
|
|
|
|
|
|   |
|   |   |   |
|   |
|   |
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |
|
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |
|   |   |   |
|   |
|   |
|
|
|   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |
|
|   |   |   |   | . |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
T | V | E | E | L | E | K | A | I | R | P | Y | E | L | I | Y | A | I | A | D | H | T | K | A | L | T | F | M | L | A | D | G | V | V | P | S | N | V | K | A | G | Y | L | A | R | L | L | I | R | K | S | I | R | H | L | R | E | L | G | L | E | V | P | . |
L | S | E | I | V | A | L | H | I | K | E | L | H | K | T | F |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
324 | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
. | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . |
  |
  |   |
347 | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | |
|
|
. | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
E | D | L | K | R | Q | Q | A | Q | V | E | Q | V | L | K | T | E | E | E | Q | F | A | R | T | L | E | R | G | L | A | L | L | D | E | E | L | A | K | L | S | G | . |
. |
. |
D | T | L | D | G | E | T | A | F | R | L | Y | D | T | Y | G | F | P | V | D | L | T | A | D | V | C | R | E | R | N | I | K | V | D | E | . |
Query Conservation |   |
|
|
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |
|   |
|   |   |   |
|   |
|
|
|
|
|
|
|
|   |
|
|
|   |   |   |
|   |
|   |
|   |   |
|
|   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|
|
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|
|
|
|
|   |
|   |
|
|
|   |   |
|
|   |
|   |
|   |   |
|
|   |   |
Template Sequence |   |
P | E | F | K | E | M | E | D | I | I | L | E | M | I | E | L | E | E | K | K | Y | A | E | T | L | R | R | G | S | D | L | V | R | R | E | I | A | K | L | K | K | K | G | I | K | E | I | P | V | E | K | L | V | T | F | Y | E | S | H | G | L | T | P | E | I | V | K | E | I | A | E | K | E | G | V | K | V | N | I | P |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | T | T | T | T |
|
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
403 | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . |
  |
  |   |
423 | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | |
|
|
. | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | F | E | A | A | M | E | E | Q | R | R | R | A | R | E | A | S | G | F | G | A | D | Y | N | A | M | I | R | V | D | S | A | S | E | F | K | G | Y | D | H | L | . |
. |
. |
E | L | N | G | K | V | T | A | L | F | V | D | G | K | A | V | D | A | I | N | A | G | Q | E | A | V | V | V | L | D | Q | T | P | F | Y |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   | . | . | . |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|
|
|
|   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |
|   |   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|
|   |
|   |
|
|
Template Sequence |   |
D | N | F | Y | S | M | V | A | K | E | A | E | R | T | L | V | D | F | E | L | L | K | D | L | . |
. |
. |
. |
. |
. |
. |
P | D | T | R | R | L | Y | Y | E | D | P | F | M | K | E | F | D | A | K | V | L | R | V | I | K | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | V | I | L | D | A | T | A | F | Y |
Template Known Secondary structure |   |
T | T |  |  |  |  |  |  |  | T | T | S |
|
|
|
| S |
| S | T | T | T | T | S | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | S |  |  |
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
483 | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 540 | . | . |
  |
  |   |
500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | E | S | G | G | Q | V | G | D | K | G | E | L | K | G | A | N | F | S | F | A | V | E | D | T | Q | K | Y | G | Q | A | I | G | H | I | G | K | L | A | A | G | S | L | K | V | G | D | A | V | Q | A | D | V | D | E | A | R | R | A | R | I | R | L | N | H | S | A | T | H | L | M | H | A | A | L | R | Q | V | L | G |
Query Conservation |   |
|
|
|
|
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |
|
|
|   |   |
|
|   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |
|   |
|   |
|   |
|   | . |   |   |   |   |
|   |   |
|
|   |
|   |   |   |
|
|   |   |
|
|   |   |   |
|
|   |
|
|
|
|
|
|
|   |   |
|
|
|   |
|
|
|
Template Sequence |   |
P | E | G | G | G | Q | P | Y | D | T | G | V | L | I | V | N | G | R | E | V | K | V | T | N | V | Q | K | V | G | K | V | I | I | H | K | V | E | . |
D | P | G | A | F | K | E | G | M | I | V | H | G | K | I | D | W | K | R | R | I | Q | H | M | R | H | H | T | G | T | H | V | L | M | G | A | L | V | R | V | L | G |
Template Known Secondary structure |   |
| S | B | T | T | B |
|
|
|
|  |  |  |  | S | S | S |
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  | S | . |
| G | G | G |
|
| T | T |
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | |
. | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . |
  |
  |   |
580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | |
|
. | . | . | . | 650 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | H | V | S | Q | K | G | S | L | V | N | D | K | V | L | R | F | D | F | S | H | N | E | A | M | K | P | E | E | I | R | A | V | E | D | L | V | N | T | Q | I | R | R | N | L | P | I | E | T | N | I | M | D | L | E | A | A | K | A | K | G | A | M | A | L | F | . |
. |
G | E | K | Y | D | E | R | V | R | V | L | S |
Query Conservation |   |
  |   |
|   |
|   |
|
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   | . | . |   |
|
|
|   |   |   |
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |
|
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |
|
|   |
|
|
|   |   |
|
|   |   |
|
|
|   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
Template Sequence |   |
R | H | V | W | Q | A | G | S | Q | L | T | T | D | W | A | R | L | D | I | S | H | Y | K | R | I | S | E | E | E | L | K | E | I | E | M | L | A | N | R | I | V | M | E | D | R | K | V | T | W | E | W | L | P | R | T | T | A | E | Q | K | Y | G | F | R | L | Y | Q | G | G | V | V | P | G | R | E | I | R | V | V | K |
Template Known Secondary structure |   |
T | T |
|
|  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
| T | T | S |
|
|
| S | S |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
629 | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . |
  |
  |   |
658 | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | G | D | F | S | T | E | L | C | G | G | T | H | A | S | R | T | G | D | I | G | L | F | R | I | I | S | E | S | G | T | A | A | G | V | R | R | I | E | A | V | T | G | E |
Query Conservation |   |
|   |   |   |
|   |
|   |
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|   |
|
|
|
|
|
|   |
|
|   |
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |
|
|   |
|
|
|   |
|
|
|
|
Template Sequence |   |
I | E | D | W | D | V | Q | A | C | G | G | T | H | L | P | S | T | G | L | V | G | P | I | K | I | L | R | T | E | R | I | Q | D | G | V | E | R | I | I | F | A | C | G | E |
Template Known Secondary structure |   |
 | T | T | T |  |  |  |  |
|
| S |
|
|
| S | B | S | G | G | G |
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
 |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
709 | 710 | . | . | . | . | . | . | . | . | . | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . | . | 750 | . | . |
  |