|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | |
|
|
. | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | I | T | K | I | T | T | Y | R | L | P | P | . |
. |
. |
R | W | M | F | L | K | I | E | T | D | E | G | V | V | G | W | G | E | P | V | I | E | G | R | A | R | T | V | E | A | A | V | H | E | . |
. |
. |
. |
. |
. |
. |
L | G | D | Y | L | I | G | Q | D | P | S | R | I | N | D | L | W | Q | V | M | Y | R | A |
Query Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | P | I | K | S | I | E | F | I | P | V | N | Y | Q | S | Q | N | T | V | V | V | K | V | T | D | E | N | G | V | Y | G | L | G | E | A | D | G | S | P | D | A | I | L | A | Y | A | N | I | E | T | E | H | K | W | L | T | N | I | T | E | K | A | I | G | R | L | P | I | E | I | N | A | I | W | D | A | X | Y | D | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |  | T |
|
|
|
| B | T | T | B |
|
| T | T | T | T | T | T | T | S |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . |
  |
  |   |
71 | . | . | . | . | |
. | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . |
Predicted Secondary structure |   |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
| . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | F | Y | R | G | . |
G | P | I | L | M | S | A | I | A | G | I | D | Q | A | L | W | D | I | K | G | K | V | L | N | A | P | V | W | Q | L | M | G | G | L | V | R | D | K | I | K | A | Y | S | W | V | G | G | D | . |
. |
. |
. |
. |
. |
. |
. |
R | P | A | D | V | I | D | G | I | K | T | L | R | E | I | G | F | D |
Query Conservation |   |
  |   |   |   |   | . |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|
|
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
T | Q | W | Q | G | X | R | G | L | G | X | F | A | L | S | G | I | D | X | A | L | Y | D | L | A | G | K | Q | L | G | V | P | A | Y | Q | L | L | G | G | T | N | K | D | K | V | H | P | Y | L | T | L | Y | P | A | I | P | D | A | S | L | D | V | A | I | K | G | Y | A | P | L | L | E | K | A | K | A | H | N | I | R |
Template Known Secondary structure |   |
T |  |  |  |  | S | S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| B |  |  |  |  | T | T |
|
| S |
| S |  |  |
|
|  |  |  |
|
|
| S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
94 | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
  |
  |   |
142 | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | F | K | L | N | G | C | E | E | L | G | L | I | D | N | S | R | A | V | D | A | A | V | N | T | V | A | Q | I | R | E | A | F | G | N | Q | I | E | F | G | L | D | F | H | G | R | V | S | . |
A | P | M | A | K | V | L | I | K | E | L | E | P | Y | R | P | L | F | I | E | E | P | V | L | A | E | Q | A | E | Y | Y |
Query Conservation |   |
  |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   | . |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |
|   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |
Template Sequence |   |
A | V | K | V | C | V | P | I | K | A | D | . |
. |
. |
. |
. |
W | S | T | K | E | V | A | Y | Y | L | R | E | L | R | G | I | L | G | H | D | T | D | X | X | V | D | Y | L | Y | R | F | T | D | W | Y | E | V | A | R | L | L | N | S | I | E | D | L | E | L | Y | F | A | E | A | T | L | Q | H | D | D | L | S | G | H |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| T | T |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |
| T | T |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | G | G | G |
|
| S |  |  |  | S |
| S |
| T | T |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
175 | . | . | . | . | 180 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
  |
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | K | L | A | A | Q | T | H | I | P | L | A | A | G | E | R | M | F | S | R | F | D | F | K | R | V | L | E | A | G | G | I | S | I | L | Q | P | D | L | S | H | A | G | G | I | T | E | C | Y | K | I | A | G | M | A | E | A | Y | D | V | T | L | A | P | H | C | P | L | G | P | I | A | L | A | A | C | L | H | I | D |
Query Conservation |   |
  |   |
|   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
Template Sequence |   |
A | K | L | V | E | N | T | R | S | R | I | C | G | A | E | X | S | T | T | R | F | E | A | E | E | W | I | T | K | G | K | V | H | L | L | Q | S | D | Y | N | R | C | G | G | L | T | E | L | R | R | I | T | E | X | A | T | A | N | N | V | Q | V | X | P | H | N | W | K | T | G | I | T | S | A | A | A | I | H | Y | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| S | S |
| B |  |  |
| T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |
|
|
| T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . |
  |
  |   |
301 | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | V | S | Y | N | A | V | L | Q | E | Q | S | M | G | I | H | Y | N | K | G | A | E | L | L | D | F | V | K | N | K | E | D | F | S | M | V | G | G | F | F | K | P | L | T | K | P | G | L | G | V | E | I | D | E | A | K | V | I | E | F |
Query Conservation |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
Template Sequence |   |
F | A | V | G | N | A | P | Y | F | E | Y | V | H | P | E | F | C | . |
. |
. |
D | G | E | L | R | K | Y | L | V | T | P | E | A | E | L | V | D | G | G | F | A | K | P | T | A | P | G | L | G | I | D | L | N | Q | E | F | L | A | S | L |
Template Known Secondary structure |   |
 |  | T |
|
| S | S |
|
|  |  |
|
| G | G | G |
| . | . | . |
|
|  |  |  |  |  | S |  |  |
|
|
|
|
| B | T | T | B |  |  |
|
|
| S | S | B | T |
|
|  |  |
|  |  |  |  |  | T |
|
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |
|
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | |
|
|
. | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . |
  |