|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | |
|
|
. | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | I | T | K | I | T | T | Y | R | L | P | P | . |
. |
. |
R | W | M | F | L | K | I | E | T | D | E | G | V | V | G | W | G | E | P | V | I | E | G | R | . |
. |
. |
. |
. |
A | R | T | V | E | A | A | V | H | E | L | G | D | Y | L | I | G | Q | D | P | S | R | I | N | D | L | W | Q | V | M | Y | R | A | G | F |
Query Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Q | K | I | I | A | M | D | L | W | H | L | A | L | P | V | C | E | I | V | V | L | R | L | V | A | E | G | G | A | E | G | F | G | E | A | S | P | W | A | V | F | T | G | T | P | E | A | S | Y | A | A | L | D | R | Y | L | R | P | L | V | I | G | R | R | V | G | D | R | V | A | I | M | D | E | A | A | R | A | V | A |
Template Known Secondary structure |   |
S | B |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |
|
|
| T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  | T | T |
| B | G | G | G |  |  |  |  |  |  |  |  |  |  |  | S | S |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
  |
  |   |
73 | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | R | G | G | P | I | L | M | S | A | I | A | G | I | D | Q | A | L | W | D | I | K | G | K | V | L | N | A | P | V | W | Q | L | M | G | G | L | V | R | D | K | I | K | A | Y | S | W | V | G | G | D | R | P | A | D | V | I | D | G | I | K | T | L | R | E | I | G | F | D | T | F | K | L | N | G | C | E | E | L | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   | . | . | . | . | . |   |   |
|   |
|
|
|
|   |
|
|
|
|   |   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |
|   | . | . | . |
Template Sequence |   |
H | C | . |
. |
. |
. |
. |
T | E | A | K | A | A | L | D | S | A | L | L | D | L | A | G | R | I | S | N | L | P | V | W | A | L | L | G | G | K | C | R | D | T | I | P | L | S | C | S | I | A | N | P | D | F | D | A | D | I | A | L | M | E | R | L | R | A | D | G | V | G | L | I | K | L | K | T | G | F | . |
. |
. |
Template Known Secondary structure |   |
S |
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| B |  |  |  |  | T | T |
|
| S |
| S |  |  |  | B |  |  |  |  |
|
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |
| S | S | . | . | . |
Template Predicted Secondary structure |   |
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
102 | . | |
|
|
|
|
. | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | |
|
|
  |
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | I | D | N | S | R | A | V | D | A | A | V | N | T | V | A | Q | I | R | E | A | F | G | N | Q | I | E | F | G | L | D | F | H | G | R | V | S | A | P | M | A | K | V | L | I | K | E | L | E | P | Y | R | P | L | F | I | E | E | P | V | L | A | E | Q | A | E | Y | Y | P | K | L | A | A | Q | T | H | I | P | L | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |   | . |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|
Template Sequence |   |
. |
. |
. |
. |
. |
R | D | H | A | F | D | I | M | R | L | E | L | I | A | R | D | F | P | . |
E | F | R | V | R | V | D | Y | N | Q | G | L | E | I | D | E | A | V | P | R | V | L | D | V | A | Q | F | Q | P | D | F | I | E | Q | P | V | R | A | H | H | F | E | L | M | A | R | L | R | G | L | T | D | V | P | L | L |
Template Known Secondary structure |   |
. | . | . | . | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | . | T | S |  |  |  |  |  |
| T | T |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |
|
| S |
| T | T |
|  |  |  |  |  |  |  |  | T | T |
| S | S |
|  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | |
. | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
  |
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | E | R | M | F | S | R | F | D | F | K | R | V | L | E | A | G | G | I | S | I | L | Q | P | D | L | S | H | A | G | G | I | T | E | C | Y | K | I | A | G | M | A | E | A | Y | D | V | T | L | A | P | H | C | P | L | . |
G | P | I | A | L | A | A | C | L | H | I | D | F | V | S | Y | N | A | V | L | Q | E | Q |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   | . |   |   |
|   |   |   |
|   |   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | D | E | S | V | Y | G | P | E | D | M | V | R | A | A | H | E | G | I | C | D | G | V | S | I | K | I | M | K | S | G | G | L | T | R | A | Q | T | V | A | R | I | A | A | A | H | G | L | M | A | Y | G | G | D | M | F | E | A | G | L | A | H | L | A | G | T | H | M | I | A | A | T | P | E | I | T | L | G | C | E |
Template Known Secondary structure |   |
 | S | T | T |
|
| S |  |  |  |  |  |  |  |  |  |  | T |
|
| S |  |  |  |  |
|  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . |
  |
  |   |
312 | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | M | G | I | H | Y | N | K | G | A | E | L | L | D | F | V | K | N | K | E | D | F | S | M | V | G | G | F | F | K | P | L | T | K | P | G | L | G | V | E | I | D | E | A | K | V | I | E | F | S | K | N | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
F | Y | Q | A | S | Y | F | L | N | E | D | I | L | E | T | P | F | R | V | E | A | G | Q | V | I | V | P | D | G | P | G | L | G | A | R | A | D | P | E | K | L | E | H | Y | A | V | R | R |
Template Known Secondary structure |   |
. | . | . | . | . |
|
|  |  |  |  | T |
| S | S |
| S | B | S | S |
|
|
|  |  | T | T |  |  |  |
|
|
| S | S | B | T | S | S |
| B |
|  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
328 | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . |
  |