|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | I | T | K | I | T | T | Y | R | L | P | P | R | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | F | L | K | I | E | T | D | E | G | V | V | G | W | G | E | P | V | I | E | G | R | . |
. |
. |
. |
. |
. |
A | R | T | V | E | A | A | V | H | E | L | G | D | Y | L | I | G | Q | D |
Query Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |
Template Sequence |   |
L | K | I | T | R | I | D | I | H | R | T | D | L | P | V | R | G | G | V | Y | R | L | S | G | G | R | E | Y | H | S | Y | D | A | T | I | V | S | I | E | T | D | T | G | L | T | G | W | G | E | S | T | P | F | G | S | T | Y | I | A | A | H | A | G | G | T | R | A | A | L | E | L | L | A | P | A | I | L | G | M | D |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  | B | S | S | S |
|  |  |  | G | G | G |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |
|
| S | T | T | S | S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
57 | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | S | R | I | N | D | L | W | Q | V | M | Y | R | A | G | F | Y | R | G | G | P | I | L | M | S | A | I | A | G | I | D | Q | A | L | W | D | I | K | G | K | V | L | N | A | P | V | W | Q | L | M | G | G | L | V | R | D | K | I | K | A | Y | S | W | V | G | G | D | R | P | A | D | V | I | D | G | I | K | T | L | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |
|   |   |
|
|
|   |
|
|
|
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
P | R | Q | H | D | R | I | W | D | R | M | R | D | T | L | K | G | H | . |
. |
. |
. |
. |
R | D | A | R | A | A | L | D | I | A | C | W | D | I | A | A | Q | A | A | G | L | P | L | C | D | M | T | G | G | R | V | A | G | P | V | P | V | I | S | S | I | G | G | D | T | P | E | A | M | R | A | K | V | A | R | H | R |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |  |  |  |  |  |  |  |
| S | S |
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| B | G | G | G | T | T | T |
|
|
| S | S |
| B |
|  |  |  |  |  |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
  |
  |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | I | G | F | D | T | F | K | L | N | G | C | E | E | L | G | L | I | D | N | S | R | A | V | D | A | A | V | N | T | V | A | Q | I | R | E | A | F | G | N | Q | I | E | F | G | L | D | F | H | G | R | V | S | A | P | M | A | K | V | L | I | K | E | L | E | P | Y | R | P | L | F | I | E | E | P | V | L | A | E | Q |
Query Conservation |   |
  |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
Template Conservation |   |
  |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   | . | . |   |
Template Sequence |   |
A | Q | G | F | K | G | H | S | I | K | I | G | A | S | E | A | . |
. |
. |
. |
E | G | G | P | A | L | D | A | E | R | I | T | A | C | L | A | D | R | Q | P | G | E | W | Y | L | A | D | A | N | N | G | L | T | V | E | H | A | L | R | M | L | S | L | L | P | P | G | L | D | I | V | L | E | A | P | C | A | . |
. |
S |
Template Known Secondary structure |   |
 |  | T |
|
|  |  |  |  |  |
|
|
|
| T | T | . | . | . | . | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |  |  |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | S |
| S | S |
|
|
|  |  |  |
|
|
| S | . | . | S |
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | |
|
|
|
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
|
. |
  |
  |   |
217 | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | |
. | 290 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
A | E | Y | Y | P | K | L | A | A | Q | T | H | I | P | L | A | A | G | E | R | M | F | S | R | F | D | F | K | R | V | L | E | A | G | G | I | S | I | L | Q | P | D | L | S | H | A | G | G | I | T | E | C | Y | K | I | A | G | M | A | E | A | Y | D | V | T | L | A | P | H | C | P | L | . |
G | P | I | A | L | A | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   | . |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
W | A | E | T | K | S | L | R | A | R | C | A | L | P | L | L | L | D | E | L | I | Q | T | E | T | D | L | I | A | A | I | R | D | D | L | C | D | G | V | G | L | K | V | S | K | Q | G | G | I | T | P | M | L | R | Q | R | A | I | A | A | A | A | G | M | V | M | S | V | Q | D | T | V | G | S | Q | I | S | F | A | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |  | S | T | T |
|
| S |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |
| S | S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
  |
  |   |
296 | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | L | H | I | D | F | V | S | Y | N | A | V | L | Q | E | Q | S | M | G | I | H | Y | N | K | G | A | E | L | L | D | F | V | K | N | K | E | D | F | S | M | V | G | G | F | F | K | P | L | T | K | P | G | L | G | V | E | I | D | E | A | K | V | I | E | F | S | K |
Query Conservation |   |
  |   |
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |
Template Sequence |   |
I | L | H | L | A | Q | S | T | P | R | H | L | L | R | C | A | L | D | T | . |
. |
. |
. |
. |
. |
R | A | M | T | T | A | E | L | A | E | I | D | A | P | L | R | D | G | G | A | S | A | P | S | D | P | G | L | G | L | R | V | N | R | D | A | L | G | T | P | V | K |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | S |
| T | T | T |  |  |  |  |  |
| G | . | . | . | . | . | . | G | G | T | B |
|
|
| S |  |  |
|
|
|
| S | B | T | T | B | B |
|
|
|
| S | S | B | T |
|
|  |  |
| G | G | G | T |
| S |
| S |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 |
  |