|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | |
|
|
|
. | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
Query Sequence |   |
M | K | I | T | K | I | T | T | Y | R | L | P | P | . |
. |
. |
. |
. |
R | W | M | F | L | K | I | E | T | D | E | G | V | V | G | W | G | E | P | V | I | E | G | R | A | . |
. |
. |
. |
R | T | V | E | A | A | V | H | E | L | G | D | Y | L | I | G | Q | D | P | S | R | I | N | D | L | W | Q | V | M | Y | R | . |
. |
Query Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
I | T | P | A | R | V | R | A | H | V | F | R | Y | P | V | H | D | R | P | A | V | L | V | E | V | E | D | S | D | G | A | V | G | W | G | E | V | W | C | N | F | P | A | C | G | A | E | H | R | A | R | L | V | E | T | V | L | A | P | L | L | T | A | R | A | F | A | D | P | A | Q | A | F | A | H | L | E | A | R | T |
Template Known Secondary structure |   |
B |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |
|
|
|
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  | T | T | S |
| B | S | S |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
A | G | F | Y | R | G | G | P | I | L | M | S | A | I | A | G | I | D | Q | A | L | W | D | I | K | G | K | V | L | N | A | P | V | W | Q | L | M | G | G | L | V | R | D | K | I | K | A | Y | S | W | V | G | G | D | R | P | A | D | V | I | D | G | I | K | T | L | R | E | I | G | F | D | T | F | K | L | N |
Query Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|   |   |
|
|   |   |
|   |
|
|   |   |
|
|
|
|   | . |   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|
Template Sequence |   |
A | V | L | A | I | Q | T | G | E | P | G | P | L | A | Q | A | I | A | G | L | D | I | A | L | C | D | L | A | A | R | R | A | G | Q | P | L | W | A | W | L | G | G | S | . |
G | D | R | I | G | V | Y | A | S | G | I | . |
. |
N | P | E | N | P | E | D | V | V | A | R | K | A | A | E | G | Y | R | A | F | K | L | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| B |  |  |  |  | T | T |
| S | . |
|
|  |  |  |  |  |  |  |  |  | . | . |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
| . |
|
|
|
|  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
101 | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | |
. | . | . | . | . | . | 150 | . | . | . | . | |
|
. | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . |
  |
  |   |
147 | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
220 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
G | C | E | E | L | G | L | I | D | N | S | R | A | V | D | A | A | V | N | T | V | A | Q | I | R | E | A | F | G | N | Q | I | E | F | G | L | D | F | H | G | R | V | S | A | P | M | A | K | V | L | I | K | E | L | E | P | Y | R | P | L | F | I | E | E | P | V | L | A | E | Q | A | E | Y | . |
Y | P | K | L | A | A |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |
|   |   |   | . |   |   |   |
|   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
|
|   | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
V | G | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
D | D | A | R | D | V | R | N | A | L | H | V | R | E | L | L | G | A | A | T | P | L | M | A | D | A | N | Q | G | W | D | L | P | R | A | R | Q | M | A | Q | R | L | G | P | A | Q | L | D | W | L | E | E | P | L | R | A | D | R | P | A | A | E | W | A | E | L | A | Q |
Template Known Secondary structure |   |
| S | S | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |
|  |  |  |  |  |
|
| S |
| T | T | S |
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
178 | . | 180 | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
  |
  |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | H | I | P | L | A | A | G | E | R | M | F | S | R | F | D | F | K | R | V | L | E | A | G | G | I | S | I | L | Q | P | D | L | S | H | A | G | G | I | T | E | C | Y | K | I | A | G | M | A | E | A | Y | D | V | T | L | A | P | H | C | P | L | G | P | I | A | L | A | A | C | L | H | I | D | F | V | S | Y | N |
Query Conservation |   |
  |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
|   |   |   |
Template Sequence |   |
A | A | P | M | P | L | A | G | G | E | N | I | A | G | V | A | A | F | E | T | A | L | A | A | R | S | L | R | V | M | Q | P | D | L | A | K | W | G | G | F | S | G | C | L | P | V | A | R | A | V | V | A | A | G | L | R | Y | C | P | H | Y | L | G | A | G | I | G | L | Q | A | S | A | H | L | L | A | A | V | P | G |
Template Known Secondary structure |   |
 |
| S | S |
|  |  |  |
| T | T |
|
| S |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |
|
|
| T | T | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
Template Predicted Secondary structure |   |
 |
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
  |
  |   |
306 | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | L | Q | E | Q | S | M | G | I | H | Y | N | K | G | A | E | L | L | D | F | V | K | N | K | E | D | F | S | M | V | G | G | F | F | K | P | L | T | K | P | G | L | G | V | E | I | D | E | A | K | V | I | E | F |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|
|   |
|   |   |   |
|   |   |   |
Template Sequence |   |
L | A | S | P | G | L | L | . |
. |
. |
G | V | D | A | N | D | N | P | L | R | S | L | L | S | P | A | L | A | T | L | H | E | G | R | I | T | L | G | G | A | P | G | L | G | V | T | P | D | L | A | A | L | R | A | A |
Template Known Secondary structure |   |
S | S | S |
|
|  |  | . | . | . |  |  |  |
| S |
|
|  |  |  |  | T | S |
| G | G | G | G | G |
|
| S | S |  |  |  |
|
| S |
| S | B | T | S |
|
|
|
|  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
329 | 330 | . | . | . | . | . | |
|
|
. | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
  |