|   |
59 | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | L | V | P | I | A | P | S | R | G | I | I | Y | D | R | N | G | I | P | L | A | L | N | R | T | I | Y | Q | I | E | M | M | P | E | K | V | D | N | V | Q | Q | T | L | D | A | L | R | S | V | V | D | L | T | D | D | D | I | A | A | F | R | K | E | R | A | R | S | H | R | F | T | S | I | P | V | K | T | N | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |
|   |
|   |
|
|   |
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |
|
Template Sequence |   |
V | R | H | I | A | I | P | A | H | R | G | L | I | T | D | R | N | G | E | P | L | A | V | S | T | P | V | T | T | L | W | A | N | P | K | E | L | M | T | A | K | E | R | W | P | Q | L | A | A | A | L | G | Q | D | T | K | L | F | A | D | R | I | E | Q | N | A | E | R | E | . |
. |
. |
F | I | Y | L | V | R | G | L |
Template Known Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  | T | T |
| G | G | G |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | T | T |
| S | . | . | . |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
53 | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | |
|
|
. | . | . | . | . | . | . | . |
  |
  |   |
139 | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | E | V | Q | V | A | R | F | A | V | N | Q | Y | R | F | P | G | V | E | V | K | G | Y | K | R | R | Y | Y | P | Y | G | S | A | L | T | H | V | I | G | Y | V | S | K | I | N | D | K | D | V | E | R | L | N | N | D | G | K | L | A | N | Y | A | A | T | H | D | I | G | K | L | G | I | E | R | Y | Y | E | D | V | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|   |   |   | . | . |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |   |   |   |
|
|
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |
|
|
|   |   |
|   |   |   |
|
Template Sequence |   |
T | P | E | Q | G | E | G | V | I | A | L | . |
. |
K | V | P | G | V | Y | S | I | E | E | F | R | R | F | Y | P | A | G | E | V | V | A | H | A | V | G | F | T | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | D | D | R | G | R | E | G | I | E | L | A | F | D | E | W | L |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  | T | T | . | . |
|
| T | T |  |  |  |  |  |  |  |  |  |  |
| T | T | G | G | G | G |  |  |  |  |
|
| B |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T | S |
| B |
| S |  |  |  |  |  | T |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
130 | . | . | . | . | . | . | . | . | . | 140 | |
|
. | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . |
  |
  |   |
219 | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | G | Q | T | G | Y | E | E | V | E | V | N | N | R | G | R | V | I | R | Q | L | K | E | V | P | P | Q | A | G | H | D | I | Y | L | T | L | D | L | K | L | Q | Q | Y | I | E | T | L | L | A | G | . |
. |
. |
. |
. |
. |
. |
S | R | A | A | V | V | V | T | D | P | R | T | G | G | V | L | A | L | V | S | T | P | S |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   | . | . | . | . | . | . | . |   |   |
|
|   |
|
|
|
|   |   |
|
|   |
|
|
|
|
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |
|   |
Template Sequence |   |
A | G | V | P | G | K | R | Q | V | L | K | D | R | V | Q | . |
. |
. |
. |
. |
. |
V | T | K | N | A | K | P | G | K | T | L | A | L | S | I | D | L | R | L | Q | Y | L | A | H | R | E | L | R | N | A | L | L | E | N | G | A | K | A | G | S | L | V | I | M | D | V | K | T | G | E | I | L | A | M | T | N | Q | P | T |
Template Known Secondary structure |   |
 |
| B |
|  |  |  |  |
|
|
|
|
|
|  | . | . | . | . | . | . |  |  | S |
|
| B |
|
|
|
|  |  | B | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |  |  | T | T | T |
| B |  |  |  |  |  |  |  | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
187 | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 |
  |
  |   |
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | |
. | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 |
Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
| . |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | D | P | N | L | F | V | D | G | I | S | S | K | D | Y | S | A | L | L | N | D | P | N | T | P | L | V | N | R | A | T | Q | G | V | Y | P | P | A | S | T | V | K | P | Y | V | A | V | S | A | L | S | A | G | V | I | T | R | N | T | T | L | F | D | . |
P | G | W | W | Q | L | P | G | S | E | K | R | Y | R | D | W |
Query Conservation |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   | . |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |   |   |   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . |   |   |   |   |   |   |
Template Sequence |   |
Y | N | P | N | N | R | R | N | L | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | A | A | M | R | N | R | A | M | I | D | V | F | E | P | G | S | T | V | K | P | F | S | M | S | A | A | L | A | S | G | R | W | K | P | S | D | I | V | D | V | Y | P | G | T | L | Q | I | G | R | . |
. |
Y | T | I | R | D | V |
Template Known Secondary structure |   |
|
| T | T |
|
| S | S |
|
| . | . | . | . | . | . | . | . | . | . | . | . | T | T | T | T |
|
|  |  |  |  |
|
| B | B |
| G | G | G | G |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| T | T |
|  |  |  |
| T | T | S |  |  |  |  | T | T | . | . |  |  |  |  |
| S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| . | . |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
268 | . | 270 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | |
|
. | . | 330 | . | . | . |
  |
  |   |
371 | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | K | W | G | H | G | R | L | N | V | T | R | S | L | E | E | S | A | D | T | F | F | Y | Q | V | A | Y | D | M | G | I | D | R | L | S | E | W | M | G | K | F | G | Y | G | H | Y | T | G | I | D | L | A | E | E | R | S | G | N | M | P | T | R | E | W | K | Q | K | R | F | K | K | P | W | Y | Q | G | D | T | I | P |
Query Conservation |   |
  |   |   |   |   |
|   |
|
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
|
|
|
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
S | R | N | S | R | Q | L | D | L | T | G | I | L | I | K | S | S | N | V | G | I | S | K | I | A | F | D | I | G | A | E | S | I | Y | S | V | M | Q | Q | V | G | L | G | Q | D | T | G | L | G | F | P | G | E | R | V | G | N | L | P | N | H | . |
. |
. |
. |
. |
. |
. |
. |
R | K | W | P | K | A | E | T | A | T |
Template Known Secondary structure |   |
. | S |
|
|
| S |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T | T | T | S |
|
| S |
|
|
| T | T |
|
|
|
| B |
|
|
|
| . | . | . | . | . | . | . | . | S | S |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
334 | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 400 | . | . | . | . |
  |
  |   |
451 | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | G | I | G | Q | G | Y | W | T | A | T | P | I | Q | M | S | K | A | L | M | I | L | I | N | D | G | I | V | K | V | P | H | L | L | M | S | T | A | E | D | G | K | Q | V | P | W | V | Q | P | H | E | P | P | V | G | D | I | H | S | G | Y | W | E | L | A | K | D | G | M | Y | G | V | A | N | R | P | N | G | T | A |
Query Conservation |   |
  |
|
|
|
|
|   |   |   |
|
|
|
|
|
|
|   |   |   |
|   |
|
|
|   |
|   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
Template Conservation |   |
  |   |
|
|
|
| . |   |   |
|
|
|
|
|
|
|   |
|   |
|   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
| . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   | . | . |   |
|
|
Template Sequence |   |
L | A | Y | G | Y | G | . |
L | S | V | T | A | I | Q | L | A | H | A | Y | A | A | L | A | N | D | G | K | S | V | P | L | S | M | T | R | V | D | R | V | P | D | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | Q | V | I | S | P | E | V | A | S | T | V | Q | G | M | L | Q | Q | V | V | E | A | . |
. |
Q | G | G |
Template Known Secondary structure |   |
 |  | T | T |
| S | . |
| B | B |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |
|
|
| B | S | B |
|
| S | S |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | . | . | T | T | S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
405 | . | . | . | . | 410 | |
. | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | |
|
. | . | 470 |
  |
  |   |
531 | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 600 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | K | Y | F | A | S | A | P | Y | K | I | A | A | K | S | G | T | A | Q | V | F | G | L | K | A | N | E | T | Y | N | A | H | K | I | A | E | R | L | R | D | H | K | L | M | T | A | F | A | P | Y | N | N | P | Q | V | A | V | A | M | I | L | E | N | G | . |
. |
. |
. |
. |
G | A | G | P | A | V | G | T | L | M | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |
|   |
|   |   |   | . | . | . | . | . |   |   |
|   |   |
|
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |
Template Sequence |   |
V | F | R | A | Q | V | P | G | Y | H | A | A | G | K | S | G | T | A | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | N | A | Y | R | S | L | F | A | G | F | A | P | A | T | D | P | R | I | A | M | V | V | V | I | D | E | P | S | K | A | G | Y | F | G | G | L | V | S | A | P | V | F | S |
Template Known Secondary structure |   |
| G | G | G |
| B | T | T | B |
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  | S | T | T | S |
|
|  |  |  |  |  |  |  |  |  |
|
| S | S |
|
|
|  |  |  |  | T |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
471 | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . |
  |
  |   |
606 | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | I | L | D | H | I | M | L | G | D | N | N | T | D | L | P | A | E | N | P | A |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |
| . | . |   |
|   |   |   |
|   |
Template Sequence |   |
K | V | M | A | G | A | L | R | L | M | N | V | . |
. |
P | P | D | N | L | P | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
| . | . |
|
|
|
| S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
544 | . | . | . | . | . | 550 | . | . | . | . | . | |
|
. | . | . | . | 560 | . | . |
  |