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Job DescriptionP27829
Confidence99.91%DateThu Jan 5 11:44:05 GMT 2012
Rank32Aligned Residues252
% Identity19%Templatec2gf2B_
PDB info PDB header:oxidoreductaseChain: B: PDB Molecule:3-hydroxyisobutyrate dehydrogenase; PDBTitle: crystal structure of human hydroxyisobutyrate dehydrogenase
Resolution2.38 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   5....10.........20.........30.........40.........50.........60.........70.........80....
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Query Sequence  TISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVP
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Template Sequence  PVGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDACKEFQDAGEQVVS. . . . . . . . . . . . . . . . SPADVAEKADRIITMLP
Template Known Secondary structure 


STTTT


SSTTTT

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S

S
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   41........50.........60.........70.........80....... ..90.........100....
 
   85....90.........100.........110.........120.........130.........140.........150.........160....
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Query Sequence  TPFKGDHEPDMTYVESAARSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPERVLPG
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Template Sequence  T. . . . . . SINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKMGAVFMDAPVSGGVGAARSGNLT. . . . . .
Template Known Secondary structure  S......STT
GGGT

TT

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   105 ....110.........120.........130.........140.........150.........160.........170..
 
   165....170.........180.........190.........200.........210.........220.........230.........240....
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Query Sequence  QVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSFRDVNIAFANELSLICADQGINVWELI
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Template Sequence  . . . . . . . . . . . FMVGGVEDEFAAAQELLGCMGSNVVYCGAVGTGQAAKICNNMLLAISMIGTAEAMNLGIRLGLDPKLLA
Template Known Secondary structure  ...........S
GGGTTTSTTTT

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   173......180.........190.........200.........210.........220.........230.........240.
 
   245....250.... .....260.........270 .........280.........290.....
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Query Sequence  RLANRHPRVN. . . . ILQPGPGVGGHCIAVD. . . . . . . . . . . . . . . . . PWFIVAQNPQQARLIRTAREVNDHK
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Template Conservation 
                                                  
   
   
            
Template Sequence  KILNMSSGRCWSSDTYNPVPGVMDGVPSANNYQGGFGTTLMAKDLGLAQDSATSTKSPILLGSLAHQIYRMM
Template Known Secondary structure  STT

TS
SSTTTSSSSGGGGTT
SSSBTT


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   242.......250.........260.........270.........280.........290.........300.........310...
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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