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Job DescriptionP27829
Confidence99.89%DateThu Jan 5 11:44:05 GMT 2012
Rank33Aligned Residues295
% Identity15%Templatec1m67A_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:glycerol-3-phosphate dehydrogenase; PDBTitle: crystal structure of leishmania mexicana gpdh complexed with inhibitor2 2-bromo-6-hydroxy-purine
Resolution2.50 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   1........10.........20.........30.........40.........50.........60.........70.........80
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Query Sequence  MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWL
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Template Sequence  LYLNKAVVFGSGAFGTALAMVLSKKCREVCVWHMNEEEVRLVNEKRENVL. . FLKGVQLASNITFTSDVEKAYNGAEIIL
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STT
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   13......20.........30.........40.........50.........60.. .......70.........80.........90
 
   81........90.........100......... 110.........120.........130.........140.........150....
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Query Sequence  IAVPTPFKGDHEPDMTYVESAARSIAPVL. . . . . . KKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNI
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Template Sequence  FVIPT. . . . . . . . . . QFLRGFFEKSGGNLIAYAKEKQVPVLVCTKGIERSTLKFPAEIIGEFLP. . . . . . . . . . SPLLSV
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   91.... ....100.........110.........120.........130.........140.... .....150
 
   155....160.........170.........180.........190.........200..... ....210.....
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Query Sequence  AYCPERVLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNS. . . . . . . . . . . . . . . . . . . RTAEMCKLTE
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Template Sequence  LAGPSFAIEVATGVFTC. . . VSIASADINVARRLQRIMSTGDRSFVCWATTDTVGCEVASAVKNVLAIGSGVANGLGMGL
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   151........160....... ..170.........180.........190.........200.........210.........220.......
 
   216...220.........230.........240........ .250.........260.........270. ..
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Query Sequence  NSFRDVNIAFANELSLICADQGINVWELIRLAN. . . . . . . . RHPRVNILQPGPGVGGHCIAVDP. . . . . . . . . . . . . . WF
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Template Conservation 
           
   

   
             
               
                 
       
  
Template Sequence  NARAALIMRGLLEIRDLTAALGGDGSAVFGLAGLGDLQLTCSSELSRNFTVGKKLGKGLPIEEIQRAVAEGVATADPLMR
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   228.230.........240.........250.........260.........270.........280.........290.........300.......
 
   274.....280.........290.........300.........310.........320.........330.........340.........350...
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Query Sequence  IVAQNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNIDDLRESPAMEIAELIAQWH
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Template Sequence  LAKQLKVKMPLCHQIYEIV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . YKKKNPRDALADLLS. C
Template Known Secondary structure  TT


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GG.G
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   311........320......... 330.........340.... .
 
   354.....360.....
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Query Sequence  SGETLVVEPNIH
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Template Sequence  GLQDEGLPPLFK
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S

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   346...350.......
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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