|   |
1 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
|
|
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
|
|
. | . | . | . | . | . | . | |
|
. | 60 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
Query Sequence |   |
M | K | K | L | V | A | T | A | . |
. |
. |
. |
. |
. |
. |
P | R | V | A | A | L | V | E | Y | E | D | R | A | I | . |
. |
. |
L | A | N | E | V | K | I | R | V | R | F | G | A | P | K | H | G | T | E | V | V | D | F | R | A | A | S | P | F | . |
. |
. |
. |
. |
I | D | E | D | F | N | G | . |
. |
E | W | Q | M | F |
Query Conservation |   |
|
|
|   |
|   |   |   | . | . | . | . | . | . | . |
|   |   |
|   |   |   |
|   |
|   |
|   |   | . | . | . |   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |   | . | . | . | . | . |   |
|   |   |   |
|   | . | . |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |
|
|   |
|   |
|   |   |   |   |
|
|
|
|
|
|   |
|   |   |
|   |   | . |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|   |
Template Sequence |   |
N | K | Q | V | I | L | K | D | Y | V | S | G | F | P | T | E | S | D | F | D | F | T | T | T | T | V | E | L | R | V | P | E | G | T | N | S | V | L | V | K | N | L | Y | L | S | C | D | P | . |
Y | M | R | I | R | M | G | K | P | D | P | S | T | A | A | L | A | Q | A | Y | T | P | G | Q | P | I | Q | G | Y | G | V |
Template Known Secondary structure |   |
 |  | B |
|  |  | S | S |
| B | S | S | S |
|
| G | G | G |  |  |
|
|  |  |  |  |  |
| S |
|
|
| S | S | S |
|  |  |  |  |  |
|  |  |  |
|
| G | . | G | G | G | T | T | T | B |
|
|
| T | T | T | T |
|
| . |
|
|
|
| T | T | S | B |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|  | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1005 | . | . | . | . | 1010 | . | . | . | . | . | . | . | . | . | 1020 | . | . | . | . | . | . | . | . | . | 1030 | . | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | . | . | . | 1050 | . | . | |
. | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . |
  |
  |   |
64 | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
140 |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
Query Sequence |   |
T | P | R | P | A | D | A | P | R | G | I | E | F | G | K | F | Q | L | G | N | M | V | V | G | D | I | I | E | C | G | S | D | V | T | D | Y | A | V | G | D | S | V | C | G | Y | G | P | L | S | E | T | V | I | I | N | A | V | N | N | Y | K | L | R | K | M | P | Q | G | S | S | W | K | N | A | V | C | . |
. |
. |
Y |
Query Conservation |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
Template Conservation |   |
|   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
Template Sequence |   |
S | R | I | I | E | S | G | H | P | D | Y | K | K | G | D | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
W | G | I | V | A | W | E | E | Y | S | V | I | T | P | M | T | H | A | H | F | K | I | Q | H | T | D | V | P | L | S | Y | Y | T | G | L | L | G | M |
Template Known Secondary structure |   |
 |  |  |  |  |
|
| S | T | T |
|
| T | T |
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  | S | B | S | S |
|  |  |
|
|
| T | T | T |
|  |  |
|
|
|
| S | S |
| G | G | G | G | G | T | T | T | S |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1084 | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . |
  |
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | P | A | Q | F | A | M | S | G | V | R | D | A | N | V | R | V | G | D | F | V | V | V | V | G | L | G | A | I | G | Q | I | A | I | Q | L | A | K | R | A | G | A | S | V | V | I | G | V | D | P | I | A | H | R | C | D | I | A | R | R | H | G | A | D | F | C | L | N | P | I | G | T | D | V | G | K | E | I | K | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
P | G | M | T | A | Y | A | G | F | Y | E | V | C | S | P | K | E | G | E | T | V | Y | V | S | A | A | S | G | A | V | G | Q | L | V | G | Q | L | A | K | M | M | G | C | Y | V | V | G | S | A | G | S | K | E | K | V | D | L | L | K | T | K | F | G | F | D | D | A | F | N | Y | K | E | E | S | D | L | T | A | A | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T | S |
|
|
| T | T |
|  |  |  |  | S | S |
| S | S | T | T |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  | S | S | T | T |  |  |  |  |  |  | T | T | T |
|
| S |  |  |  |  | T | T | T |
| S | S |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1139 | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . |
  |
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | |
|
|
|
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | G | K | Q | G | A | D | V | I | I | E | T | S | G | Y | A | D | A | L | Q | S | A | L | R | G | L | A | Y | G | G | T | I | S | Y | V | A | F | A | . |
. |
. |
. |
K | P | F | A | E | G | F | N | L | G | R | E | A | H | F | N | N | A | K | I | V | F | S | R | A | C | S | E | P | N | P | D | Y | P | R | W | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |
Template Sequence |   |
K | R | C | F | P | N | G | I | D | I | Y | F | E | N | V | G | G | K | M | L | D | A | V | L | V | N | M | N | M | H | G | R | I | A | V | C | G | M | I | S | Q | Y | N | L | E | N | Q | E | G | V | H | N | L | S | N | I | I | Y | K | R | N | R | I | Q | G | F | V | V | S | D | F | Y | D | K | Y | . |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |
| T | T |
| B | S |  |  |  |  | S | S |
| T |  |  |  |  |  |  |  |  |  | B |
| T | T |
|  |  |  |  |
|
|
| T | T | G | G | G |
| S | S |
|
|
|
|
|
| G | G | G | G | G | T | S |
|
|  |  |  |  |
|
| G | G | G | G | T | T | T | T | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1219 | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | |
|
|
|
|
  |
  |   |
297 | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | K | R | I | E | E | T | C | W | E | L | L | M | N | G | Y | L | N | C | E | D | L | I | D | P | V | V | T | F | A | N | S | P | E | S | Y | M | Q | Y | V | D | Q | H | P | E | Q | S | I | K | M | G | V | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |
|
|   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
. |   |   |   |
|   |   |   |   |   |
|
|   |   |
|   |
|   | . | . |   |   |
|   |   |
|   |   |
|
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |
| . | . |
|
|
|
|   |
Template Sequence |   |
. |
S | K | F | L | E | F | V | L | P | H | I | R | E | G | K | I | T | . |
. |
Y | V | E | D | V | A | D | G | L | E | K | A | P | E | A | L | V | G | L | F | H | G | K | N | V | G | . |
. |
K | Q | V | V | V |
Template Known Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
|
| . | . |
|
|  |  |
|
| B | S | G | G | G |  |  |  |  |  |  |  | T | T | T | T |
|
| S | S | . | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
. |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
1294 | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | 1310 | |
|
. | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . | . | . | 1330 | . | . | . | . | . | . | |
|
. | . | . | 1340 | . |
  |