|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | |
. | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | |
|
|
. | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
I | F | T | L | R | P | Y | Q | Q | E | A | V | D | A | T | L | N | H | F | R | R | H | K | . |
T | P | A | V | I | V | L | P | T | G | A | G | K | S | L | V | I | A | E | L | A | R | L | A | . |
. |
. |
R | G | R | V | L | V | L | A | H | V | K | E | L | V | A | Q | N | H | A | K | Y | Q | A | L | G | L | E | A | . |
Query Conservation |   |
  |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |
|
|   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |
|
|   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |
|
|
|
|
|
|   |   |
|
|   |
|
|   |   |   |
|
|
|
|   |
|
|
|
|
|   |   |
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
P | F | E | T | T | P | D | Q | A | Q | A | I | N | A | V | L | S | D | M | C | Q | P | L | A | M | D | R | L | V | C | G | D | V | G | F | G | K | T | E | V | A | M | R | A | A | F | L | A | V | D | N | H | K | Q | V | A | V | L | V | P | T | T | L | L | A | Q | Q | H | Y | D | N | F | R | D | R | F | A | N | W | P |
Template Known Secondary structure |   |
| S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S |
|
|  |  |  |  |  |
|
|
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
598 | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
77 | . | . | 80 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . |
Predicted Secondary structure |   |
. | . | . |
|  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
D | I | F | A | A | G | L | K | R | K | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | H | G | K | V | V | F | G | S | V | Q | S | V | A | R | N | L | D | A | F | Q | G | E | F | S | L | L | I | V | D | E | C | H | R | I | G | D | D | E | E | S | Q | Y | Q | Q | I | L | T | H | L | T | K | V | N | P | H |
Query Conservation |   |
. | . | . |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   | . | . |
|   |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |   |   | . | . | . | . | . | . | . |
|   |
|   |   |   |   |   |   |
Template Sequence |   |
V | R | I | E | M | I | S | R | F | R | S | A | K | E | Q | T | Q | I | L | A | E | V | A | E | G | K | I | D | I | L | I | G | T | H | K | L | L | Q | S | D | V | K | . |
. |
F | K | D | L | G | L | L | I | V | D | E | E | H | R | F | G | V | R | H | K | . |
. |
. |
. |
. |
. |
. |
E | R | I | K | A | M | R | A | N |
Template Known Secondary structure |   |
|
|  |  |  |  | S | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |
| T |  |  |  |  | S |
|
|
| . | . |
| S | S |  |  |  |  |  |  |  | S | G | G | G | S |
|  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
| . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
678 | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | |
|
720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
740 | . | . | . | . | . | . | . | . |
  |
  |   |
144 | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | L | L | G | L | T | A | T | P | F | R | L | G | K | G | W | I | Y | Q | F | H | Y | H | G | M | V | R | G | D | E | K | A | L | F | R | D | C | I | Y | E | L | P | L | R | Y | M | I | K | H | G | Y | L | T | P | P | E | R | L | D | M | P | V | V | Q | Y | D | F | S | R | L | Q | A | Q | S | N | G | L | F | S |
Query Conservation |   |
  |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|   |
|
|
|
|
|
|
|
|
|
| . |   |   |   |
|   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
V | D | I | L | T | L | T | A | T | P | I | P | R | T | L | . |
N | M | A | M | S | G | M | R | D | L | S | I | I | A | T | P | P | A | R | R | L | A | V | K | T | F | V | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S |  |  |  |  |  |  | S | S |
|
|
|  |  |  | . |  |  |  |  | T | T | T | S |  |  |  |  |
|
|
|
|
|
| B |
| B |
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  | . |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
749 | 750 | . | . | . | . | . | . | . | . | . | 760 | . | . | . | |
. | . | . | . | . | . | 770 | . | . | . | . | . | . | . | . | . | 780 | . | . | . | . | . | . | . | . | . | 790 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
|
|
|
. | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | A | D | L | N | R | E | L | K | K | Q | Q | R | I | T | P | H | I | I | S | Q | I | M | E | F | A | A | T | R | K | G | V | M | I | F | A | A | T | V | E | H | A | K | E | I | V | G | L | L | P | . |
. |
. |
. |
A | E | D | A | A | L | I | T | G | D | T | P | G | A | E | R | D | V | L | I | E | N | F | K | A | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |
|
|
|
|
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | Y | D | S | M | V | V | R | E | A | I | L | R | E | I | L | R | G | G | Q | V | Y | Y | L | Y | N | D | V | E | N | I | Q | K | A | A | E | R | L | A | E | L | V | P | E | A | R | I | A | I | G | H | G | Q | M | R | E | R | E | L | E | R | V | M | N | D | F | H | H | Q |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
792 | . | . | . | . | . | . | . | 800 | . | . | . | . | . | . | . | . | . | 810 | . | . | . | . | . | . | . | . | . | 820 | . | . | . | . | . | . | . | . | . | 830 | . | . | . | . | . | . | . | . | . | 840 | . | . | . | . | . | . | . | . | . | 850 | . | . | . | . | . | . | . | . | . | 860 |
  |
  |   |
300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | F | R | Y | L | V | N | V | A | V | L | T | T | G | F | D | A | P | H | V | D | L | I | A | I | L | R | P | T | E | . |
S | V | S | L | Y | Q | Q | I | V | G | R | G | L | R | L | A | P | G | K | T | D | C | L | I | L |
Query Conservation |   |
  |   |   |
|
|
|   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |   |
|
|   |   |   |   |   |   | . |
|   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
|
|   |   |
|
|   |   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|   |   |   | . |   |   |   |   |   |   |   |
Template Sequence |   |
R | F | N | V | L | V | C | T | T | I | I | E | T | G | I | D | I | P | T | A | N | T | I | I | I | E | R | A | D | H | F | G | L | A | Q | L | H | Q | L | R | G | R | V | G | R | S | H | H | . |
Q | A | Y | A | W | L | L |
Template Known Secondary structure |   |
S |
|
|  |  |  |  | S | S | T | T | G | G | G | S |
|
| T | T |  |  |  |  |  |  | T | T | T | T | S | S |
|  |  |  |  |  |  |  |  | T | T |
|
| B | T | T | B | . |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
861 | . | . | . | . | . | . | . | . | 870 | . | . | . | . | . | . | . | . | . | 880 | . | . | . | . | . | . | . | . | . | 890 | . | . | . | . | . | . | . | . | . | 900 | . | . | . | . | . | . | . | . | |
. | 910 | . | . | . | . | . |
  |