Job Description P60560 Confidence 99.94% Date Thu Jan 5 12:06:53 GMT 2012 Rank 46 Aligned Residues 255 % Identity 17% Template c2fptA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors Resolution 2.40 Å

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		11	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.
Predicted Secondary structure																																																																										.	.	.	.	.	.	.	.
Query SS confidence																																																																										.	.	.	.	.	.	.	.
Query Sequence		F	K	D	V	L	I	R	P	K	R	S	T	L	K	S	R	S	D	V	E	L	E	R	Q	F	T	F	K	H	S	G	Q	S	W	S	G	V	P	I	I	A	A	N	M	D	T	V	G	T	F	S	M	A	S	A	L	A	S	F	D	I	L	T	A	V	H	K	H	Y	S	V	E	.	.	.	.	.	.	.	.
Query Conservation																																																																										.	.	.	.	.	.	.	.
Alig confidence											.	.	.	.	.	.											.	.	.	.	.														.																													.	.	.	.	.	.	.	.
Template Conservation											.	.	.	.	.	.											.	.	.	.	.														.
Template Sequence		F	T	S	L	G	L	L	P	F	.	.	.	.	.	.	Q	D	S	D	M	L	E	V	R	V	.	.	.	.	.	L	G	H	K	F	R	N	P	V	G	I	A	A	.	G	F	D	K	H	G	E	A	V	D	G	L	Y	K	M	G	F	G	F	V	E	I	G	S	V	T	P	K	P	Q	E	G	N	P	R	P
Template Known Secondary structure					T	T					.	.	.	.	.	.				G	G	G					.	.	.	.	.	T	T				S	S	S					T	.	T	T	T	T	T	S	S								T	T		S									S	S		B			S		S
Template Predicted Secondary structure											.	.	.	.	.	.											.	.	.	.	.														.
Template SS confidence
		62	.	.	.	.	.	.	.	70							.	.	.	.	.	.	.	.	.	80						.	.	.	.	.	.	.	.	.	90	.	.	.		.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.
																															83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.					.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.
Query SS confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.
Query Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	E	W	Q	A	F	I	N	N	S	S	A	D	V	L	K	H	V	M	V	S	T	G	T	S	.	.	.	.	D	A	D	F	E	K	T	K	Q	I	L	D	L	N	P	A	L	N	F	V	C	I	D
Query Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.
Template Conservation
Template Sequence		R	V	F	R	L	P	E	D	Q	A	V	I	N	R	Y	G	F	N	S	H	G	L	S	V	V	E	H	R	L	R	A	R	Q	Q	K	Q	A	K	L	T	E	D	G	L	P	L	G	V	N	L	G	K	N	K	T	S	V	D	A	A	E	D	Y	A	E	G	V	R	V	L	G	P	L	A	D	Y	L	V	V	N
Template Known Secondary structure							G	G	G	T										B												T	T										T	T											T	T		S														G	G	G		S
Template Predicted Secondary structure
Template SS confidence
		133	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.
		130	.	.	.	.																	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.							.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.
Predicted Secondary structure							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.	.
Query SS confidence							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.	.
Query Sequence		V	A	N	G	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	E	H	F	V	Q	F	V	A	K	A	R	E	A	W	P	T	K	T	I	C	A	G	N	V	V	T	G	E	M	.	.	.	.	.	.	C	E	E	L	I	L	S	G	A	D	I	V	K	V	G	I	G	P	G	S	V	C	T
Query Conservation							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.	.	.	.
Alig confidence							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																	.														.	.	.	.	.	.
Template Conservation																																							.
Template Sequence		V	S	S	P	N	T	A	G	L	R	S	L	Q	G	K	A	E	L	R	R	L	L	T	K	V	L	Q	E	R	D	G	L	R	R	V	H	R	.	P	A	V	L	V	K	I	A	P	D	L	T	S	Q	D	K	E	D	I	A	S	V	V	K	E	L	G	I	D	G	L	I	V	T	N	T	T	V	S	R	P	A
Template Known Secondary structure					T	T	S	T	T	S	G	G	G	G	S																	T	S		G	G	G		.									S																		T										B	S				T
Template Predicted Secondary structure																																							.
Template SS confidence
		213	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.		250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.
		188	.	190	.	.	.	.	.	.	.												.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.
Predicted Secondary structure												.	.	.	.	.	.	.	.	.	.	.
Query SS confidence												.	.	.	.	.	.	.	.	.	.	.
Query Sequence		T	R	V	K	T	G	V	G	Y	P	.	.	.	.	.	.	.	.	.	.	.	Q	L	S	A	V	I	E	C	A	D	A	A	H	G	L	G	G	M	I	V	S	D	G	G	C	T	T	P	G	D	V	A	K	A	F	G	G	G	A	D	F	V	M	L	G	G	M	L	A	G	H	E	E	S	G	G	R	I	V
Query Conservation												.	.	.	.	.	.	.	.	.	.	.
Alig confidence												.	.	.	.	.	.	.	.	.	.	.															.																																				.	.						.	.
Template Conservation																																					.																																				.	.						.	.
Template Sequence		G	L	Q	G	A	L	R	S	E	T	G	G	L	S	G	K	P	L	R	D	L	S	T	Q	T	I	R	E	M	Y	A	L	T	Q	G	.	R	V	P	I	I	G	V	G	G	V	S	S	G	Q	D	A	L	E	K	I	R	A	G	A	S	L	V	Q	L	Y	T	A	L	T	F	.	.	W	G	P	P	V	.	.
Template Known Secondary structure		T				T	T	T	T	S	S	S																						T	T	T	.		S						S	S			S											T		S					S						.	.			T			.	.
Template Predicted Secondary structure																																					.																																				.	.						.	.
Template SS confidence
		292	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.		.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.			.	.	.	.	.
		257	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	E	N	G	E	K	F	M	L	F	Y	G	M	S	S	E	S	A	M	K	R	H	V	G	G	V	A	E	Y	R	A	A	E	G	K	T	V	K	L	P	L	R	G	P	V	E	N	T	A	R	D	I	L	G	G	L	R	S	A	C	T	Y	V	G	A	S	R	L	K	E	L	T	K	R	T
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	V	G	K	V	K	R	E	L	E	A	L	L	K	E	Q	G	F	G	G	V	T	D	A	I	G	A	D
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.															T	T		S	S					T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																																																		367	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.

No model constructed - rank, confidence too low

---

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions