|   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
220 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  | . |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | T | S | G | C | H | N | S | M | S | L | A | L | M | A | V | C | K | P | G | D | I | V | A | V | E | S | P | C | Y | Y | G | S | M | Q | M | L | R | G | M | G | V | K | V | I | E | I | . |
P | T | D | P | E | T | G | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
S | V | E | A | L | E | L | A | L | E | Q | W | P | I |
Query Conservation |   |
  |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
| . |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|   |
|
|   |
|   |
|   |
|   |   |   |   |
|
|   |
|
|
|   |
|
|
|
|
|
|
|   |   |
|
|   |
|
|
|
|   |
|
|
|
|   |
|   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|   |
Template Sequence |   |
M | V | T | N | G | T | S | T | A | N | K | I | V | G | M | Y | S | A | P | A | G | S | T | I | L | I | D | R | N | C | H | K | S | L | T | H | L | M | M | M | S | D | V | T | P | I | Y | F | R | P | T | R | N | A | Y | G | I | L | G | G | I | P | Q | S | E | F | Q | H | A | T | I | A | K | R | V | K | E | T | P | N |
Template Known Secondary structure |   |
 |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T |
|  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |
|
|  |  |
| T | T |
|
|  |  |
|
|
| G | G | G | G | S |  |  |  |  |  |  |  |  |  |  | S | T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
215 | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . |
  |
  |   |
242 | |
|
|
|
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
. | . | . | . | 290 | |
|
|
. | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . |
Predicted Secondary structure |   |
| . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  | . |  |
|
|
|
| . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
Query SS confidence |   |
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | . |
. |
. |
. |
. |
G | I | I | L | V | P | N | C | N | N | P | L | G | F | I | M | P | D | A | R | K | R | A | V | L | S | L | A | Q | R | H | D | I | V | I | F | E | D | D | V | Y | G | E | . |
L | A | T | E | Y | . |
. |
. |
P | R | P | R | T | I | H | S | W | D | I | D | G | R | V | L | L | C | S | S | F | S |
Query Conservation |   |
  | . | . | . | . | . |   |
|   |   |   |
|   |   |   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|   |   | . |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|
Alig confidence |   |
| . | . | . | . | . |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |
|
|
|
|
|
| . | . | . |
|
|   |
|
|   |   |
| . | . | . |
|   |   |
|   |   |   |   |   |   |   |   | . | . |
|
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|
Template Sequence |   |
A | T | W | P | V | H | A | V | I | T | N | S | . |
. |
. |
T | Y | D | G | L | L | Y | N | . |
. |
. |
T | D | F | I | K | K | T | L | D | V | K | S | . |
. |
I | H | F | D | S | A | W | V | P | Y | T | N | F | S | P | I | Y | E | G | K | C | G | M | S | G | G | R | V | E | G | K | V | I | Y | E | T | Q | S | T | H |
Template Known Secondary structure |   |
|
| S |
| S |  |  |  |  |  | S | S | . | . | . |
| T | T |
|  |  |  |
| . | . | . |  |  |  |  |  |  |  |
|
|
| S |  | . | . |  |  |  |  |
| T | T |
| T | T | G | G | G | S | G | G | G | T | T | S | S | T | T | S | S |
|
|
| T | T |
|  |  |  |  |  |  |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
295 | . | . | . | . | 300 | . | . | . | . | . | . | |
|
|
. | . | . | 310 | . | . | . | . | |
|
|
. | . | . | . | . | 320 | . | . | . | . | . | . | |
|
. | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . |
  |
  |   |
313 | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | S | I | A | P | G | L | R | V | G | W | V | A | P | G | R | . |
. |
. |
. |
. |
. |
Y | H | D | K | L | M | H | M | K | Y | A | I | S | S | F | N | V | P | S | T | Q | M | A | A | A | T | F | V | L | E | G | H | Y | H | R | H | I | R | R | M | R | Q | I | Y | Q | R | N | L | A | L | Y | T | C | W | I | R | E | Y |
Query Conservation |   |
|   |   |   |   |
|   |
|   |
|   |
|   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
| . |
|
|
|
|
|
|   |
|   |
|
|
|   |   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |
|   |   |   |   |
Template Sequence |   |
L | . |
L | A | A | F | S | Q | A | S | M | I | H | V | K | G | D | V | N | E | E | T | F | N | E | A | Y | M | M | H | T | T | T | S | P | H | Y | G | I | V | A | S | T | E | T | A | A | A | M | M | K | G | N | A | G | K | R | L | I | N | G | S | I | E | R | A | I | K | F | R | K | E | I | K | R | L | R | T | E | S |
Template Known Secondary structure |   |
| . |
| S |
|
| T | T |
|  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  | S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
| . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
368 | |
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . |
  |
  |   |
387 | . | . | 390 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 400 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | P | C | E | I | C | I | T | R | P | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | G | F | L | L | W | I | E | L | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | V | D | M | V | C | V | A | R | Q | L | C | R | M | K | I | Q | V | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |
|   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |
|   |
|
|   |   | . |
Template Sequence |   |
D | G | W | F | F | D | V | W | Q | P | D | H | I | D | T | T | E | C | W | P | L | R | S | D | S | T | W | H | G | F | K | N | I | D | N | E | H | M | Y | L | D | P | I | K | V | T | L | L | T | P | G | M | E | K | D | G | T | M | S | D | F | G | I | P | A | S | I | V | A | K | Y | L | D | E | H | G | I | V | V | . |
Template Known Secondary structure |   |
S | S |
|
|
|  |  | S | S |
| S |
|
|
| S |
| S |
|  |  |
|
| T | T |
|
| T | T |
|
| T | T |
|
| S | S | S |  |  |  |
| T | T |  |  |  |  |  |
| S | S | B |
| S | S | S |
| B |
| S | S |
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
447 | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | |
  |
  |   |
428 | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | |
. | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . |
Predicted Secondary structure |   |
 |
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | S | I | F | S | A | S | G | K | Y | R | N | C | L | R | I | N | C | A | . |
L | P | L | S | E | T | Y | R | E | A | L | K | Q | I | G | E | A |
Query Conservation |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |   | . |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|   |
|   |   |
|   |   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
E | K | T | G | P | Y | N | L | L | F | L | F | S | I | G | I | D | K | T | K | A | L | S | L | L | R | A | L | T | D | F |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | S |  |  |
| S | S |  |  |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
526 | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . |
  |