Job Description P39389 Confidence 99.97% Date Thu Jan 5 12:00:20 GMT 2012 Rank 84 Aligned Residues 394 % Identity 15% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		25	.	.	.	.			30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.
Predicted Secondary structure							.	.
Query SS confidence							.	.
Query Sequence		K	L	P	S	V	.	.	R	S	L	S	Q	E	H	G	V	S	I	S	T	V	Q	Q	A	Y	Q	T	L	E	T	M	K	L	I	T	P	Q	P	R	S	G	Y	F	V	A	Q	R	K	A	Q	P	P	V	P	P	M	T	R	P	V	Q	R	P	V	E	I	T	Q	W	D	Q	V	L	D	M	L	E	A	H	S
Query Conservation							.	.
Alig confidence							.	.																											.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																			.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		E	L	P	A	D	T	V	Q	R	I	A	A	E	L	K	C	H	P	T	D	E	R	V	A	L	H	L	D	E	E	D	K	L	.	.	.	R	H	F	R	E	F	Y	I	P	K	I	Q	D	L	P	P	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	L	S	L	V	N	K
Template Known Secondary structure																T	S		T	T	S										T		T	T	.	.	.	G	G	G	G			B			B	G	G	G	S	T	T		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.		G	G	G	S		T
Template Predicted Secondary structure																																			.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		7	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.				40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.																					.	.	.	60	.	.	.
		103	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.				.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.
Predicted Secondary structure																																												.	.	.
Query SS confidence																																												.	.	.
Query Sequence		D	S	S	I	V	P	L	S	K	S	T	P	D	V	E	A	P	S	L	K	P	L	W	R	E	L	S	R	V	V	Q	H	N	L	Q	T	V	L	G	Y	D	L	.	.	.	L	A	G	Q	R	V	L	R	E	Q	I	A	R	L	M	L	D	S	G	S	V	V	T	A	D	D	I	I	I	T	S	G	C	H	N
Query Conservation																																												.	.	.
Alig confidence																																												.	.	.																	.	.	.	.	.
Template Conservation																																																															.	.	.	.	.
Template Sequence		D	E	N	A	I	Y	F	L	G	N	S	L	G	L	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	.	.	.	.	.	A	N	E	K	E	I	A	L	M	N	A	L	T	V
Template Known Secondary structure		T		B					B	T	T	T	S			B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T	.	.	.	.	.			G	G	G					S
Template Predicted Secondary structure																																																															.	.	.	.	.
Template SS confidence
		65	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.						.	.	.	.	130	.	.	.	.	.	.	.	.	.
		180	.	.	.	.	.	.	.	.	.	190	.				.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.										.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.		.	240	.	.	.	.	.	.
Predicted Secondary structure														.	.	.																						.	.	.	.	.	.	.	.	.																											.
Query SS confidence														.	.	.																						.	.	.	.	.	.	.	.	.																											.
Query Sequence		S	M	S	L	A	L	M	A	V	C	K	P	.	.	.	G	D	I	V	A	V	E	S	P	C	Y	Y	G	S	M	Q	M	L	R	G	M	.	.	.	.	.	.	.	.	.	G	V	K	V	I	E	I	P	T	D	P	E	T	G	I	S	V	E	A	L	E	L	A	L	E	Q	.	W	P	I	K	G	I	I	L
Query Conservation														.	.	.																						.	.	.	.	.	.	.	.	.																											.
Alig confidence														.	.	.																						.	.	.	.	.	.	.	.	.																											.
Template Conservation
Template Sequence		N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L
Template Known Secondary structure															S	S	S							T	T																T	T														T	T		S	S														G	G	G
Template Predicted Secondary structure
Template SS confidence
		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.
		247	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		V	P	N	C	N	N	P	L	G	F	I	M	P	D	A	R	K	R	A	V	L	S	L	A	Q	R	H	D	I	V	I	F	E	D	D	V	Y	G	E	L	A	T	E	Y	P	R	P	R	T	I	H	S	W	D	I	D	G	R	V	L	L	C	S	S	F	S	K	S	I	A	P	G	L	R	V	G	W	V	A	P
Query Conservation
Alig confidence															.	.	.																								.	.	.	.											.
Template Conservation															.	.	.																								.	.	.	.											.
Template Sequence		F	S	G	V	H	F	Y	T	G	Q	H	F	N	.	.	.	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	.	.	.	.	G	N	V	E	L	Y	L	H	D	W	.	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H
Template Known Secondary structure				S	B		T	T	T		B	B			.	.	.											T	T								T	T	T	T	.	.	.	.	T	T	S								.	T								S	S	S	T	T				T	T
Template Predicted Secondary structure															.	.	.																								.	.	.	.											.
Template SS confidence
		220	.	.	.	.	.	.	.	.	.	230	.	.				.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.					.	.	.	.	260	.	.	.	.	.		.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.
		327	.	.	330	.	.	.	.	.	.	.																									.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.
Predicted Secondary structure													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		G	R	Y	H	D	K	L	M	H	M	K	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	A	I	S	S	F	N	V	P	S	T	Q	M	A	A	A	T	F	V	L	E	G	H	Y	H	R	H	I	R	R	M	R	Q	I	Y	Q	R	N	L	A	L	Y	T	C	W
Query Conservation													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L
Template Known Secondary structure		G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		292	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.
		383	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.					.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.			.	.	450	.	.	.	.	.	.
Predicted Secondary structure																		.	.	.	.																																																		.	.
Query SS confidence																		.	.	.	.																																																		.	.
Query Sequence		I	R	E	Y	F	P	C	E	I	C	I	T	R	P	K	G	.	.	.	.	G	F	L	L	W	I	E	L	P	E	Q	V	D	M	V	C	V	A	R	Q	L	C	R	M	K	I	Q	V	A	A	G	S	I	F	S	A	S	G	K	Y	R	N	C	L	R	I	N	C	A	.	.	L	P	L	S	E	T	Y	R	E
Query Conservation																		.	.	.	.																																																		.	.
Alig confidence								.										.	.	.	.											.	.																					.	.	.	.	.	.	.	.										.	.
Template Conservation								.																								.	.																					.	.	.	.	.	.	.	.
Template Sequence		I	K	H	N	Y	G	.	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	.	.	P	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	.	.	.	.	.	.	.	.	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K
Template Known Secondary structure								.						S		S	S	G	G	G	B		S									.	.	T	T									T	T	T							T	.	.	.	.	.	.	.	.	T	T					B			T	T	T
Template Predicted Secondary structure								.																								.	.																					.	.	.	.	.	.	.	.
Template SS confidence
		372	.	.	.	.	.		.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400			.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420									.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440
		457	.	.	460	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	L	K	Q	I	G	E	A	V
Query Conservation
Alig confidence
Template Conservation
Template Sequence		F	T	N	L	L	T	S	I	L
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		450	.	.	.	.	.	.	.	.