|   |
97 | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
. | . | . | . | . | . | . | 170 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
| . |
|
|
|
|
|  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | L | E | A | H | S | D | S | S | I | V | P | L | S | K | S | T | P | D | V | E | A | P | S | L | K | P | L | W | R | E | L | S | R | V | V | Q | H | N | L | Q | T | V | L | G | Y | D | L | L | A | G | Q | R | V | L | R | E | Q | I | A | R | L | M | L | D | S | . |
G | S | V | V | T | A | D | D | I | I | I | T | S |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   | . | . | . | . | . |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
| . | . |   |   |   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|   |
Template Sequence |   |
I | K | W | G | V | L | K | E | K | E | L | P | X | W | I | A | E | X | D | F | K | I | A | P | . |
. |
. |
. |
. |
E | I | X | A | S | X | E | E | K | L | K | V | A | A | F | G | Y | . |
. |
E | S | V | P | A | E | Y | Y | K | A | V | A | D | W | E | E | I | E | H | R | A | R | P | K | E | D | W | C | V | F | A | S |
Template Known Secondary structure |   |
T | T | T | T | T |
|
| T | T |
|  |  |
|
| S | S |
|
| S | S |
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
| G | G | G |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
  |
  |   |
176 | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | |
|
|
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | C | H | N | S | M | S | L | A | L | M | A | V | C | K | P | G | D | I | V | A | V | E | S | P | C | Y | Y | G | S | M | Q | M | L | R | G | M | G | V | K | V | I | E | I | P | T | D | P | E | T | G | . |
. |
. |
I | S | V | E | A | L | E | L | A | L | E | Q | W | P | I | K | G | I | I | L | V | P | N | C | N | N |
Query Conservation |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
| . | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . |   |   |   |
|
Template Sequence |   |
G | V | V | P | A | I | S | A | X | V | R | Q | F | T | S | P | G | D | Q | I | L | V | Q | E | P | V | Y | N | X | F | Y | S | V | I | E | G | N | G | R | R | V | I | S | S | D | L | I | Y | E | N | S | K | Y | S | V | N | W | A | D | L | E | E | K | L | A | T | P | S | V | R | X | X | V | F | C | . |
N | P | H | N |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T |
|  |  |  |  |
| S | S |
|
| T |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |
|
|
|  |  |  | T | T |  |  |  |
|
|  |  |  |  |  |  |  |  | T | S | T | T |  |  |  |  |  |  |  | . | S | S | B | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | |
. | . | . | 170 |
  |
  |   |
253 | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | |
. | . | . | . | . | . | . | 310 | . | . | . | . | . | . | |
. | . | . | 320 | . | . | . | |
. | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
| . |
|
|  |  |  |
|
|
|
|
|
|
|
|
| . |
|
|
|  |  |  |  | . |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
P | L | G | F | I | M | P | D | A | R | K | R | A | V | L | S | L | A | Q | R | H | D | I | V | I | F | E | D | D | V | Y | G | E | L | A | T | E | Y | P | R | P | R | T | I | H | S | W | D | I | D | . |
G | R | V | L | L | C | S | S | F | S | K | S | I | A | . |
P | G | L | R | V | G | W | . |
V | A | P | G | R | Y |
Query Conservation |   |
|
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |
|
|   |   |   |
|   |
|
|   |   |   | . |   |
|   |
|   |
|   | . |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
P | I | G | Y | A | W | S | E | E | E | V | K | R | I | A | E | L | C | A | K | H | Q | V | L | L | I | S | D | E | I | H | G | D | L | V | L | T | D | E | D | I | T | P | A | F | T | V | D | W | D | A | K | N | W | V | V | S | L | I | S | P | S | T | F | N | L | A | A | L | H | A | A | C | A | I | I | P | N | P | D |
Template Known Secondary structure |   |
T | T | T | B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| T | T | G | G | G | B |
| S | S |
|
|
|
|
| G | G | G | S |
| T | T | G | G | G | G |  |  |  |  |  |
|
|
|
|
| S |
| G | G | G |
|
|  |  |  |  |
|
| S |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
  |
  |   |
330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
H | D | K | L | M | H | M | K | Y | A | I | S | S | F | N | V | P | S | T | Q | M | A | A | A | T | F | V | L | E | G | H | Y | H | R | H | I | R | R | M | R | Q | I | Y | Q | R | N | L | A | L | Y | T | C | W | I | R | E | Y | F | P | C | E | I | C | I | T | R | P | K | G | G | F | L | L | W | I | E | L | P | E | . |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |
|   |
|   |   |   |
|   |
|   |   |   |   |   |
Template Sequence |   |
L | R | A | R | A | E | E | S | F | F | L | A | G | I | G | E | P | N | L | L | A | I | P | A | A | I | A | A | Y | E | E | G | H | D | W | L | R | E | L | K | Q | V | L | R | D | N | F | A | Y | A | R | E | F | L | A | K | E | V | P | . |
E | V | K | V | L | D | S | N | A | S | Y | L | A | W | V | D | I | S | A | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | . | T | S |  |  |
|
|
| S | B | S | S |  |  |  |  |  |
| G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
252 | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | |
. | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
  |
  |   |
409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
. | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | V | D | M | V | C | V | A | R | Q | L | C | R | M | . |
K | I | Q | V | A | A | G | S | I | F | S | A | S | G | K | Y | R | N | C | L | R | I | N | C | A | L | P | L | S | E | T | Y | R | E | A | L | K | Q | I | G | E | A | V | Y | R |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|   |   |   | . |
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |   | . | . |   |   |   |
|
|
|
|   |   | . |   |   |   |
|   |
|   |   |
|   |   |
|
|   |   |
|
|   |   |
Template Sequence |   |
G | X | N | A | E | D | F | C | K | Y | L | R | E | K | T | G | L | I | I | S | A | G | N | G | Y | R | G | N | G | . |
. |
H | E | F | V | R | I | N | L | A | . |
C | P | K | E | L | V | I | D | G | X | Q | R | L | K | Q | G | V | L | N |
Template Known Secondary structure |   |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |
|  |  | G | G | G | G |
| T | T | G | . | . | G | G |  |  |  |  |  |
|
| . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |
|
|
|
|
| . | . |
|
|  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
331 | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | |
|
360 | . | . | . | . | . | . | . | . | |
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . |
  |