|   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | Q | V | A | K | E | N | N | F | A | L | P | A | V | N | C | V | G | T | D | S | I | N | A | V | L | E | T | A | A | K | V | K | A | P | V | I | V | Q | F | S | N | G | G | A | S | F | I | A | G | K | G | V | K | S | D | V | P | Q | G | A | A | I | L | G | A | I | S | G | A | H | H | V | H | Q | M | A | E | H | Y |
Query Conservation |   |
|   |   |
|   |   |   |   |
|
|
|   |
|
|
|
|   |
|   |
|   |   |   |
|
|
|   |
|
|
|   |   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|
|
|   |   | . | . | . | . |
|   |
|
|
|   |
|
|   |   |
|
|   |   |   |
|   |
|   |
|
|   | . | . | . | . | . | . | . |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
M | H | R | L | I | E | E | H | G | S | V | L | M | P | G | V | Q | D | A | L | S | A | A | V | V | . |
. |
. |
. |
E | K | T | G | F | H | A | A | F | V | S | G | Y | S | V | S | A | A | M | L | G | L | . |
. |
. |
. |
. |
. |
. |
P | D | F | G | L | L | T | T | T | E | V | V | E | A | T | R | R | I | T | A | A | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S | S | S |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  | . | . | . | . |  |  | T | T |
| S |  |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
| S | S | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
31 | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
102 | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
G | V | P | V | I | L | H | T | D | H | C | A | K | K | L | L | P | W | I | D | G | L | L | D | A | G | E | K | H | F | A | A | T | G | K | P | L | F | S | S | H | M | I | D | L | S | E | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | L | Q | E | N | I | E | I | C | S | K | Y | L | E | R | M | S | K |
Query Conservation |   |
. |   |
|
|
|
|
|
|
|
|
|
|   |   |   |   |
|
|   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|
|
|
|   |
|   |
|
|
| . |   |   |   |   |
| . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |
|
|
|   |
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |   |
Template Sequence |   |
P | N | L | C | V | V | V | D | G | D | T | G | G | G | . |
G | P | L | N | V | . |
. |
. |
. |
. |
. |
. |
Q | R | F | I | R | E | L | I | S | A | G | A | K | G | V | F | L | E | D | Q | V | W | P | K | K | C | G | H | M | R | G | K | A | V | V | P | A | E | E | H | A | L | K | I | A | A | A | R | E | A | I | G | D |
Template Known Secondary structure |   |
S | S | S |  |  |  |  |  |
| T | T |
| S | S | . | S |  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |
| B |
| S | S |
|
|
| S | S | S | S |
|
|
| B |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
| . |
|  |  |  |  | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | |
. | . | . | . | . | |
|
|
|
|
|
|
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . |
  |
  |   |
168 | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | G | M | T | L | E | I | E | L | G | C | T | G | G | E | E | D | G | V | D | N | S | H | M | D | A | S | A | L | Y | T | Q | P | E | D | V | D | Y | A | Y | T | E | L | S | K | I | S | P | R | F | T | I | A | A | S | F | G | N | V | H | G | V | Y | K | P | G | N | V | V | L | T | P | T | I | L | R | D | S | Q | E |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |
|
|   |   |
|
|
|
|   |
|
|
|
|
|
|
|   |
|
|   |
|
|   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   |
|
|
|
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|
|   |
|
|   |
|
|   |
|
| . |
|
|
|   |
|
|
|   | . | . | . | . | . | . | . | . | . | . |   |   |   | . | . |   |   |
|   |
|   |   |   |   |   |
Template Sequence |   |
S | D | F | F | L | V | A | R | T | D | A | R | A | P | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | L | E | E | G | I | R | R | A | N | L | Y | K | E | A | . |
G | A | D | A | T | F | V | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | P | A | . |
. |
N | V | D | E | L | K | E | V | S | A |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |
| T |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | . | T |
| S |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
| . | . | S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . |
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
172 | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | |
. | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
210 | . | . | |
|
. | . | . | . | . | . | . | 220 | . | . |
  |
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | |
|
. | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  | . | . |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | V | S | K | K | H | N | L | P | H | N | S | L | N | F | V | . |
. |
F | H | G | G | S | G | S | T | A | Q | E | I | K | D | S | V | S | Y | G | V | V | K | M | N | I | D | T | D | T | Q | W | A | T | W | E | G | V | L | N | Y | Y | K | A |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
| . | . |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |
|
|
|
|   |
|
|
|   |   |
|   |   |   |
|
|
|   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
K | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
K | G | L | R | I | A | N | M | I | E | G | G | K | T | P | L | H | T | P | E | E | F | K | E | M | G | F | H | L | I | A | H | S | L | T | A | V | Y | A | T | A | R | A | L | V | N | I | M | K | I |
Template Known Secondary structure |   |
 | S | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  |  |
| T | T | S | S | S |
|
|
|
|  |  |  |  |  |  |  | T |
|
|  |  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
| . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
223 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
  |