|   |
267 | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
330 | . | . | . | . | . | . | . | . | . | 340 |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | K | S | D | K | I | T | T | T | L | D | A | G | L | Q | R | R | L | E | E | L | A | Q | N | W | K | G | R | L | P | P | R | S | S | L | A | M | I | V | V | D | H | T | D | M | R | V | R | G | W | V | G | S | V | D | L | N | D | D | S | R | F | G | . |
. |
. |
. |
. |
. |
H | V | D | M | V | N | S | I | R | S | P |
Query Conservation |   |
  |   |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |
|   |   |   |
|   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   | . |
|
|   |
|
|
|
|   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|
Template Sequence |   |
Q | N | G | K | D | I | I | L | S | L | D | Q | R | I | Q | T | L | A | Y | E | E | L | N | K | A | V | E | Y | H | Q | A | K | A | . |
G | T | V | V | V | L | D | A | R | T | G | E | I | L | A | L | A | N | T | P | A | Y | D | P | N | R | P | G | R | A | D | S | E | Q | R | R | N | R | A | V | T | D | X | I | E | P |
Template Known Secondary structure |   |
B |
|
|
|
|  |  | B | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  | . |  |  |  |  |  |  |  | T | T | T |
| B |  |  |  |  |  |  |  | S |
|
|
| T | T | S |
| T | T |
|
|  |  |  |  |
|
|  |  |  |  |
|
| B |
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | |
. | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
  |
  |   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | S | V | L | K | P | F | V | Y | G | L | A | L | D | E | G | L | I | H | P | A | S | L | L | Q | D | V | P | R | R | T | G | D | Y | R | P | G | N | F | D | S | G | F | H | G | P | I | S | M | S | E | A | L | V | R | S | L | N | L | P | A | V | Q | V | L | E | A | Y | G | P | K | R | F | A | A | K | L | R | N | V |
Query Conservation |   |
|
|
|   |
|
|
|   |
|
|
|
|
|
|   |
|   |
|
|
|   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
|   |
|
|   |   |   |
|
|   |   |
|   |
|
|   |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | S | A | I | K | P | F | V | I | A | K | A | L | D | A | G | K | T | D | L | N | E | R | L | N | T | Q | P | Y | K | I | G | P | S | P | . |
. |
V | R | D | T | H | V | Y | P | S | L | D | V | R | G | I | X | Q | K | S | S | N | V | G | T | S | K | L | S | A | R | F | G | A | E | E | X | Y | D | F | Y | H | E | L |
Template Known Secondary structure |   |
G | G | G | G |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
| S | S |
|
|  |  |
| S |
|  |  |  | T | T |  |  | . | . |  |
|
| S | S |
|
| S |  |  |
|  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|  |  |  |
|
|
|  |  |  |
|
|  |  | . | . |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
309 | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | |
|
. | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . |
  |
  |   |
421 | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | |
440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | L | P | L | Y | L | P | N | G | A | A | P | N | L | S | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | L | G | . |
G | A | G | A | K | L | E | D | M | A | A | A | Y | T | A | F | A | R | H | G | K | A | G | K | L | R | L | Q | P | D | D | P | L | L | E | R | P | L | M | S | S | G | A | A |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| . |   |   |   |
|
|
|
|
|
|
|   |
|
|
|   |
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
|
|
|
|
|   |   |   |
|
|
|
|
|   |
|   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |
Template Sequence |   |
G | I | G | V | R | X | H | S | G | F | P | G | E | T | A | G | L | L | R | N | W | R | R | W | R | P | I | E | Q | A | T | X | S | F | G | Y | G | L | Q | L | S | L | L | Q | L | A | R | A | Y | T | A | L | T | H | D | G | V | L | L | P | L | S | F | E | K | Q | A | V | A | P | Q | G | K | R | I | F | K | E | T | A |
Template Known Secondary structure |   |
T | T | T | S |
|
|
|
| S |
| T | T |
|
|
|
|  |  |
|
| G | G | G |
|
|  |  |  |  |  |  |  |  | T | T |
| S |  |  | B |
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |
|
|
| B | S | B |
|
| S | S |
|
|
|
|  |  |
| S |
|
|
|  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
387 | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . |
  |
  |   |
484 | . | . | . | . | . | 490 | . | . | . | . | . | . | |
. | . | . | 500 | . | . | . | |
. | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | |
. | . | . | . | . | . | . | |
|
|
|
. | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | I | I | R | R | I | M | A | D | E | A | Q | P | . |
L | P | D | S | A | L | P | . |
R | V | A | P | L | A | W | K | T | G | T | S | Y | G | Y | R | D | . |
A | W | A | I | G | V | N | . |
. |
. |
. |
A | R | Y | V | I | G | I | W | T | G | R | P | D | G | T | P | V | V | G | Q | F | G | F | A | S | A | V | P | L |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |
|   |   |   | . |
|
|   |   |   |   |   | . |   |   |   |   |
|
|
|
|
|
|
|
|   |   |   |
|
| . |
|
|
|
|
|   |
| . | . | . | . |
|   |
|
|
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |
|
|
|
|
Template Sequence |   |
R | E | V | R | N | L | X | V | S | V | T | E | P | G | G | T | G | T | A | G | A | V | D | G | F | D | V | G | A | K | T | G | T | A | R | K | N | K | H | V | A | T | F | I | G | F | A | P | A | K | N | P | R | V | I | V | A | V | T | I | D | E | P | T | A | H | . |
. |
. |
G | Y | Y | G | G | V | V | A | G | P | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T | T | S | T | T | S | S |
| G | G | G |
|
| T | T | S |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | S | T | T | S |
|
|  |  |  |  |  |  |  |  |
|
|
| S | S | . | . | . |
|
|
|  |  |  |  | T |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
468 | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | |
|
|
. | . | . | . | . | . | 540 | . | . | . | . |
  |
  |   |
557 | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | N | Q | V | N | N | I | L | L | S | R | S | A | N | L | P | E | D | P |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|
Template Sequence |   |
F | K | K | I | X | G | G | S | L | N | I | L | G | I | S | P | T | K | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
553 | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . |
  |