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Job DescriptionP76577
Confidence100.00%DateThu Jan 5 12:24:46 GMT 2012
Rank3Aligned Residues549
% Identity22%Templatec2olvA_
PDB info PDB header:transferaseChain: A: PDB Molecule:penicillin-binding protein 2; PDBTitle: structural insight into the transglycosylation step of bacterial cell2 wall biosynthesis : donor ligand complex
Resolution2.80 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   38.40.........50.........60.........70.........80.........90.........100.........110.......
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Query Sequence  EVNPARVVVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWQDLTSGRVISGGS
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Template Sequence  QDPIPAKIYDKNGELVKTLDNGQ. . RHEHVNLKDVPKSXKDAVLATEDNRFYEHGALDYKRLFGAI. . . . . . . . . GKGAS
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B


TTS

STT
..SB



STTS

TT
SS
SSS
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   70.........80.........90.. .......100.........110.........120.........130... .....
 
   118.120...... ...130.........140.........150.........160.........170.........180.........190......
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Query Sequence  TLTMQVARL. LDPHPKTFGGKIRQLWRALQLEWHLSKREILTLYLNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAML
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Template Sequence  TLTQQVVKDAFLSQHKSIGRKAQEAYLSYRLEQEYSKDDIFQVYLNKIYYSDGVTGIKAAAKYYFNKDLKDLNLAEEAYL
Template Known Secondary structure 
TTT

S

TTTS

B
STT
BS


STT

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   148.150.........160.........170.........180.........190.........200.........210.........220.......
 
   197..200.........210.........220.........230.........240........ .250.........260....
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Query Sequence  AVLPQAPSRLRPDRWPERAEAARNKVLERMAVQGVWSREQVKESREEPIWLA. . . . . . . . . . . . PRQMPQLAPLFSRMML
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Template Sequence  AGLPQVPNNYNIYDHPKAAEDRKNTVLYLXHYHKRITDKQWEDAKKIDLKANLVNRTPEERQNIDTNQDSEYNSYVNFVK
Template Known Secondary structure  GGGS
TTT
TTSS
TTS
TTTT




S




TTGGG
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   228.230.........240.........250.........260.........270.........280.........290.........300.......
 
   265. ...270.........280.........290.........300.........310.........320........
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Query Sequence  GK. . . . . . . . . . . . . . . . SKSDKITTTLDAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRF
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Template Sequence  SELXNNKAFKDENLGNVLQSGIKIYTNXDKDVQKTLQNDVDNGSFYKNKDQQVGATILDSKTGGLVAISGGRDFKDVV. .
Template Known Secondary structure  SSTTTTSS
TTBT
S





SSTTTTT
BSSTT

TTT..
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   308.310.........320.........330.........340.........350.........360.........370.........380.....
 
   329330.........340........ .350.........360........ .370.........380.........390.........400......
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Query Sequence  GHVDMVNSIRSPGSVLKPFV. YGLALDEGLIHPASLLQDVP. RRTGDYRPGNFDSGFHGPISMSEALVRSLNLPAVQVLE
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Template Sequence  . NRNQATDPHPTGSSLKPFLAYGPAIENXKWATNHAIQDESSYQVDGSTFRNYDTKSHGTVSIYDALRQSFNIPALKAWQ
Template Known Secondary structure  .S

TTSS

GGGGT


TTB

S
SSS


SS
S


TT
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   386...390.........400.........410.........420.........430.........440.........450.........460....
 
   407..410.........420.........430......... 440.........450.........460......... 470....
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Query Sequence  AYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILG. . GAGAKLEDMAAAYTAFARHGKAGKLRLQPD. . . . . . . . . . DPLLE
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Template Sequence  SVKQNAGNDAPKKFAAKLGLNYEGDIGPSEVLGGSASEFSPTQLASAFAAIANGGTYNNAHSIQKVVTRDGETIEYDHTS
Template Known Secondary structure  T
TTTTT


SS


TT
TT

TTS

B

TTS




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   465....470.........480.........490.........500.........510.........520.........530.........540....
 
   475....480.........490...... ...500... ......510.... .....520.........530........
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Query Sequence  RPLMSSGAAWIIRRIMADEAQP. LPDSALP. RVAPLAWKTGT. . . . . . . . . . . . . . SYGYRDAWAIGVNARYVIGIWTGR
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Template Sequence  HKAXSDYTAYXLAEXLKGTFKPYGSAYGHGVSGVNXGAKTGTGTYGAETYSQYNLPDNAAKDVWINGFTPQYTXSVWXGF
Template Known Secondary structure 
S
GGGSSTTSTTTT


SS





TT

TTS
SS
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   545....550.........560.........570.........580.........590.........600.........610.........620....
 
   539540..... ....550.........560.........570.........580. ........590.........600.....
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Query Sequence  PDGTPVV. . . . . GQFGFASAVPLLNQVNNILLSRSANLPEDPRPNSVT. RGVICWPGGQSLPEGDGNCRRRLA
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Template Sequence  SKVKQYGENSFVGHSQQEYPQFLYENVXSKI. . SSRDGEDFKRPSSVSGSIPSINVSGSQ. . . DNNTTNRSTH
Template Known Secondary structure  SS

GGGTTSST..


S






SSTTTT

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   625....630.........640.........650..... ....660.........670.........680.. .......690..
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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