|   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | K | S | R | R | V | W | I | F | T | T | G | D | A | T | A | E | E | R | P | L | A | V | L | L | D | G | E | F | W | A | Q | S | M | P | V | W | P | . |
. |
. |
. |
. |
. |
V | L | T | S | L | T | H | R | Q | Q | L | P | P | A | V | Y | V | L | I | D | A | I | D | T | T | H | R | A | H | E | L | P | C | N | A | D |
Query Conservation |   |
|   |   |
|   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
|
|   |
|   |   |   |
|   |   |   |
|   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |   |
|   |   | . | . |   |   |   |   |
| . |
|
|
|
|
|
|   |   |   |
|   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |
|
|   | . | . | . | . |
|   |   |   |
|   |   |
|   |
|   |
|   |   |   | . | . |   |   |   |   |
Template Sequence |   |
V | D | Q | M | Y | V | R | Y | Q | I | P | Q | R | . |
. |
A | K | R | Y | P | . |
I | T | L | I | H | G | C | C | L | T | G | M | T | W | E | T | T | P | D | G | R | M | G | W | D | E | Y | F | L | R | K | G | Y | S | . |
. |
. |
. |
T | Y | V | I | D | Q | S | G | R | G | R | S | A | T | D | . |
. |
I | S | A | I |
Template Known Secondary structure |   |
 | S |
|  |  |  |  |  |  |  |  | T | T | . | . |
|
| S | S |
| . |  |  |  |  |
|
| T | T |
|
| G | G | G | G | S | S |
| T | T | S |
|
|
|  |  |  |  |  |  |  | T | T |
|
| . | . | . | . |  |  |  |  |  |
| T | T | S | T | T | S |
|
|
| . | . |
|  |  |  |
Template Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |
|
|
|
| . | . |
|
|
|
|  | . |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
47 | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
60 | . | . | . | . | |
. | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | |
|
. | . | . | . |
  |
  |   |
224 | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
F | W | L | A | V | Q | Q | E | L | L | P | L | V | K | A | I | A | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | S | D | R | A |
Query Conservation |   |
  |   |   |   |
|   |   |
|
|   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
N | A | V | K | L | G | K | A | P | A | S | S | L | P | D | L | F | A | A | G | H | E | A | A | W | A | I | F | R | F | G | P | R | Y | P | D | A | F | K | D | T | Q | F | P | V | Q | A | Q | A | E | L | W | Q | Q | M | V | P | D | W | L | G | S | M | P | T | P | N | P | T | V | A | N | L | S | K | L | A | I | K | L |
Template Known Secondary structure |   |
 |  |  |  | T | T | S | S |
| G | G | G | S |
|
|
| B |
|
|
|  |  |  |  |  |  |  | T | T | S | S | S | B | T | T | B |
|
| T | T |
|
| S |
| G | G | G |  |  |  |  |  |  |  |
|
|
| B |
| G | G | G | S |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
118 | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
D | R | T | V | V | A | G | Q | S | F | G | G | L | S | A | L | Y | A | G | L | H | W | P | E | R | F | G | C | V | L | S | Q | S | G | S | Y | W | W | P | H | R | G | G | Q | Q | E | G | V | L | L | E | K | L | K | A | G | E | V | S | A | E | G | L | R | I | V | L | E | A | G | I | R | E | P | M | I | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |
|   |
|   |
|   |
|
|   |   |
|   |   |   |
|
|   |   |
|
|   |
|   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
D | G | T | V | L | L | S | H | S | Q | S | G | I | Y | P | F | Q | T | A | A | M | N | P | K | G | I | T | A | I | V | S | V | E | P | G | E | C | P | K | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | V | K | P | L | T | S | I | P | V | L | V | V | F | G | D | H | I | E | E | F | P | R | W | A |
Template Known Secondary structure |   |
T | S |  |  |  |  |  |  | G | G | G | T | T |  |  |  |  |  |  |  |  |
|
| T | T |  |  |  |  |  |  |  | S |
| S |
|
|
|
| G | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G |
| G | G | G | T | T | S |
|  |  |  |  |  |
| S | S |
| T | T |
| T | T | T |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . |
  |
  |   |
|
|
323 | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 350 | . | |
|
|
. | . | . | . | . | . | . | . | 360 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
M | R | A | N | Q | A | L | Y | A | Q | L | H | P | I | K | E | S | I | F | W | R | Q | V | D | . |
. |
. |
. |
. |
. |
G | G | H | D | A | . |
. |
. |
L | C | W | R | G | G | L | M | Q | G | L | I | D | L |
Query Conservation |   |
. | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . |
|
|
|
|   | . | . | . |   |   |
|
|   |   |
|   |
|   |
|   |   |
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |
|   |
|   |
|
|   |   |   |   |
|   |
|   |   |   |
|
|   |   |
|   |   |
|
|
Template Sequence |   |
P | R | L | K | A | C | H | A | F | I | D | A | L | N | A | A | G | G | K | G | Q | L | M | S | L | P | A | L | G | V | H | G | N | S | H | M | M | M | Q | D | R | N | N | L | Q | V | A | D | L | I | L | D | W | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  | G | G | G | G | T |
|
|
|
|
| T | T | G | G | G | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
264 | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . |
  |