Return to main results Retrieve Phyre Job Id

Job DescriptionP52647
Confidence99.82%DateThu Jan 5 12:05:59 GMT 2012
Rank13Aligned Residues477
% Identity10%Templatec2w93A_
PDB info PDB header:lyaseChain: A: PDB Molecule:pyruvate decarboxylase isozyme 1; PDBTitle: crystal structure of the saccharomyces cerevisiae pyruvate2 decarboxylase variant e477q in complex with the surrogate3 pyruvamide
Resolution1.60 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   4.....10..... ....20.........30.........40.........50.........60......... 70.........80.
Predicted Secondary structure  .



















.


Query SS confidence 











.





















































.











Query Sequence  IDGNGAVASVAF. RTSEVIAIYPITPSSTMAEQADAWAGNGLKNVWGDTPRVVEMQSEAGAIATVHG. ALQTGALSTSFT
Query Conservation 







  
 .

  


 








 
 
      
  
  
    
   
 
  
   
 
.

 




 
 
Alig confidence 











.























..........



















.











Template Conservation 
    

   
   

  


 

     
  

   ..........  
  
    
  
   
 
 
  

  

  
Template Sequence  ITLGKYLFERLKQVNVNTVFGLPGDFNLSLLDKIYEV. . . . . . . . . . EGMRWAGNANELNAAYAADGYARIKGMSCIITT
Template Known Secondary structure  TT




GGGGGGGS..........TT



S
S
Template Predicted Secondary structure 












..........









Template SS confidence 















































































   4.....10.........20.........30.........40 .........50.........60.........70...
 
   82.......90.........100.........110. ........120.........130.........140.........150...
Predicted Secondary structure 









........















Query SS confidence 





























. . . . . . . .









































Query Sequence  SSQGLLLMIPTLYKLAGELTPFVLHVAART. . . . . . . . VATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISQ
Query Conservation 
  

 

 
 
   

   
 

 

 
 ........     

   

 
   

 

  

 
 
 


 
 
  

Alig confidence 





























........









































Template Conservation   


  
    
  
     


 
 
                       
         
    
            
 
Template Sequence  FGVGELSALNGIAGSYAEHVGVLHVVGVPSISSQAKQLLLHHTLGNGDFTVFHRMSANISETTAMITDIATAPAEIDRCI
Template Known Secondary structure  TTTT



TT


TTS
SSS
SSTT
S


TTT
Template Predicted Secondary structure 



























Template SS confidence 















































































   74.....80.........90.........100.........110.........120.........130.........140.........150...
 
   154.....160.........170.........180.........190.........200.........210.........220.........230...
Predicted Secondary structure 







































Query SS confidence 















































































Query Sequence  IATLKSRVPFIHFFDGFRTSHEINKIVPLADDTILDLMPQVEIDAHRARALNPEHPVIRGTSANPDTYFQSREATNPWYN
Query Conservation   



   


 
 

 
 

    

    
 
                
 
  
   
                    
Alig confidence 














.

























.....................................
Template Conservation    
    


 
 

. 
                        ..................................... 
Template Sequence  RTTYVTQRPVYLGLP. ANLVDLNVPAKLLQTPIDMSLKPNDA. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . E
Template Known Secondary structure  TS
.TTGGGSGGGGGS



S




.....................................
Template Predicted Secondary structure 






.

























.....................................
Template SS confidence 















































































   154.....160........ .170.........180.........190.... .
 
   234.....240.........250.........260.........270...... ...280.........290.........
Predicted Secondary structure 
















...





...........
Query SS confidence 










































. . .






















. . . . . . . . . . .
Query Sequence  AVYDHVEQAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAI. . . GTCEEVVDELLTRGEKVGVLKVR. . . . . . . . . . .
Query Conservation       
           

 
  

  
  


 


  

  ...  
 


  
   
 







...........
Alig confidence 














................











...






















...........
Template Conservation              
  ................






 
 
     
   
  


    

  
   

      
  
Template Sequence  SEKEVIDTILALVKD. . . . . . . . . . . . . . . . AKNPVILADACCSRHDVKAETKKLIDLTQFPAFVTPMGKGSIDEQHPRY
Template Known Secondary structure  ................
SS
TT




TTTTTSS
TTSTT
Template Predicted Secondary structure 

................
























Template SS confidence 















































































   196...200.........210 .........220.........230.........240.........250.........
 
   300.........310.........320.........330.........340.........350.........360.........370......
Predicted Secondary structure  ...






































Query SS confidence  . . .












































































Query Sequence  . . . LYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAEPLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCV
Query Conservation  ...   


   
   
  
 
 
 



         

  

  

            
 
 
  


   

 
  
Alig confidence  ...
















.






......................





























Template Conservation   
   
          
   .
 

  
......................      
 
  
                  
Template Sequence  GGVYVGTLSKPEVKEAVESA. DLILSVG. . . . . . . . . . . . . . . . . . . . . . ALTKNIVEFHSDHMKIRNATFPGVQMKFVL
Template Known Secondary structure 

GGGS
T
.SS......................





SSTTT

Template Predicted Secondary structure 











.

......................
















Template SS confidence 















































































   260.........270......... 280...... ...290.........300.........310......
 
   377..380.........390.........400.........410.........420.........430.........440.........450......
Predicted Secondary structure 





















































Query SS confidence 















































































Query Sequence  LAVFAELNAAKPKARFTVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQGYFVYD
Query Conservation   

   
    
   
  
     
   

   
 

 

 

  
  
   


 
 
   


    
        

Alig confidence 






































.................










............
Template Conservation     
  
                                .................    
   
  ............ 
Template Sequence  QKLLTNIADAAKGYKPVAVPARTPANAAVPASTPLKQEW. . . . . . . . . . . . . . . . . MWNQLGNFLQE. . . . . . . . . . . . G
Template Known Secondary structure  TTT
















TT
B

.................GGGT

T............T
Template Predicted Secondary structure 














.................


............
Template SS confidence 















































































   331........340.........350.........360......... 370.........380 .
 
   457..460.........470.........480.........490.........500.... .....510.........520.........530....
Predicted Secondary structure 



























..










Query SS confidence 















































. .





























Query Sequence  SKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERL. . KPGGIFLLNTPYSADEVWSRLPQEVQAVLN
Query Conservation 
 


 
  
 

    

     
  

 
 
   
      
   
..  

  



  


    


        
Alig confidence 















































..


















.









Template Conservation       
 
                         

  
  




 
         

   




   .  

 

   
Template Sequence  DVVIAETGTSAFGINQTTFPNNTYGISQVLWGSIGFTTGATLGAAFAAEEIDPKKRVILFIGDGSLQLT. VQEISTMIRW
Template Known Secondary structure 

TTGGGS


SS


TTT

TT
TT

.TTT
Template Predicted Secondary structure 




























.
Template SS confidence 















































































   382.......390.........400.........410.........420.........430.........440.........450 .........460
 
   535....540.........550.........560.........570.........580.........590.........600 .........610.
Predicted Secondary structure 





















.
Query SS confidence 

































































.










Query Sequence  QKKARFYVINAAKIARECGLAARINTVMQMAFFHLTQILPGDSALAELQGAIAKSYSSKGQDLVER. NWQALALARES
Query Conservation     
 
 



  



 
        




 

   
  
     
 
 
 
  
 
   

  .
  

      
Alig confidence 
























..............


























.










Template Conservation     
 


 

 
 
          ..............        
    
 
 
  
     
    

  

  
Template Sequence  GLKPYLFVLNNDGYTIQKLIHGPKA. . . . . . . . . . . . . . QYNEIQGWDHLSLLPTFGAKDYETHRVATTGEWDKLTQD
Template Known Secondary structure  T


SSS
TTS
TT
..............GGG





GGGTT
SS
BT
Template Predicted Secondary structure 











..............















Template SS confidence 













































































   461........470.........480..... ....490.........500.........510.........520....
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions