|   |
59 | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | |
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | E | A | G | A | I | A | T | V | H | G | A | L | Q | T | G | A | L | S | T | S | F | T | . |
S | S | Q | G | L | L | L | M | I | P | T | L | Y | K | L | A | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | L | T | P | F | V | L | H | V | A | A | R | T | V | A | T | H | A | L | S | I | F | G | D | H | S | D | V | M | A |
Query Conservation |   |
  |
|   |   |
|   |   |   |
|   |
|
|
|   |
|
|
|
|
|   |
|   |
| . |
|   |   |
|
|   |
|
|   |
|   |
|   |   |   |
|
| . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |
|
|   |   |   |
|
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|
|   |
|
|
|
|
|   |   |
|   |   |
|
|
|   |   |   |   |   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |
|
Template Sequence |   |
S | E | X | G | F | A | G | I | A | V | G | A | A | X | A | G | L | R | P | I | C | E | F | X | T | F | N | F | S | X | Q | A | I | D | Q | V | I | N | S | A | A | K | T | Y | Y | X | S | G | G | L | Q | P | V | P | I | V | F | R | G | P | N | . |
G | A | S | A | G | V | A | A | Q | H | S | Q | C | F | A | A | W | Y |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S | S | G | G | G | G | G | G | T |  |  |  |  |  |  | T | T | T | T |  |  |  |  | T | T | S | S |
|
|
|
|
|  |  |  |  |  |
| . | S |
|
| S | S |
|
| G | G | G |
|
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
58 | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
  |
  |   |
129 | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | R | Q | T | G | C | A | M | L | C | A | A | N | V | Q | E | A | Q | D | F | A | L | I | S | Q | I | A | T | L | K | S | R | V | P | F | I | H | F | F | D | G | F | R | T | S | H | E | I | N | K | I | V | P | L | A | D | D | T | I | L | D | L | M | P | Q | V | E | I | D | A | H | R | A | R | A | L | N | P | E | H |
Query Conservation |   |
|
|   |
|
|   |   |
|
|   |
|   |
|   |
|
|
|   |
|   |
|   |   |
|
|   |
|
|
|
|   |   |   |
|
|
|   |
|   |
|
|   |
|   |
|
|   |   |   |   |
|
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|
|
|
|   |
|   |   |
|
|
|   |   |
|   |   |   |   |
|   |   |
|   |   | . | . | . | . |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | H | C | P | G | L | K | V | V | S | P | W | N | S | E | D | A | K | G | L | I | K | S | A | I | R | . |
. |
. |
. |
D | N | N | P | V | V | V | L | E | N | E | L | X | Y | G | V | P | F | E | F | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 | T | S | T | T |
|  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | S | S | S |
|  |  |  |  |  |
| T | T | T | T | T |
|  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | |
|
|
|
. | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | V | I | R | G | T | S | A | N | P | D | T | Y | F | Q | S | R | E | A | T | N | P | W | Y | N | A | V | Y | D | H | V | E | Q | A | M | N | D | F | S | A | A | T | G | R | Q | Y | Q | P | F | E | Y | Y | G | H | P | Q | A | E | R | V | I | I | L | M | G | S | A | I | G | T | C | E | E | V | V | D | E | L | L | T |
Query Conservation |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |
|
|
|   |   |
|
|   |   |   |   |
|   |
|
|
|   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   | . |   |
|   |
|
|
|
|
|
|   |
|   |   |
|   |   |
|
|   |
|
|   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | A | Q | S | K | D | F | L | I | P | I | G | K | A | K | I | E | R | . |
Q | G | T | H | I | T | V | V | S | H | S | R | P | V | G | H | C | L | E | A | A | A | V | L | S | K |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | S | T | T |
|
|
|
| T | T |
|
|  |  |  |  | . |
|
| S | S |  |  |  |  |  |
| S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  | . |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
184 | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
. | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
  |
  |   |
289 | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | G | E | K | V | G | V | L | K | V | R | L | Y | R | P | F | S | A | K | H | L | L | Q | A | L | P | G | S | V | R | S | V | A | V | L | D | R | T | K | E | P | G | A | Q | A | E | P | L | Y | L | D | V | M | T | A | L | A | E | A | F | N | N | G | E | R | E | T | L | P | R | V | I | G | G | R | Y | G | L | S | S |
Query Conservation |   |
  |
|   |
|
|
|
|
|
|
|
|   |   |   |
|
|
|   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |
|
|
|   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |   | . |   |   |
|
|
|
|
|
|   |   |   |   |
|
|   |
| . | . | . | . |   |   |
|   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |
Template Sequence |   |
E | G | V | E | C | E | V | I | N | X | R | T | I | R | P | X | D | X | E | T | I | E | A | S | V | X | K | T | . |
N | H | L | V | T | V | E | G | G | W | P | Q | F | G | V | G | . |
. |
. |
. |
A | E | I | C | A | R | I | X | E | G | P | A | F | N | F | L | D | A | P | A | V | R | V | T | G | A | D | V | P | X | P |
Template Known Secondary structure |   |
T | T |
|
|  |  |  |  |  |
|
|  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  |  | . | S |
|  |  |  |  |
| S | S |
| S | T | T | S |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  | S | T | T | G | G | G |
| S | S |
|
|  |  |  |
|
|
| S | S |
|
|
|
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
229 | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | |
. | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
|
|
|
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
  |
  |   |
|
|
|
|
|
|
369 | 370 | . | |
|
. | . | . | . | . | . | . | . | 380 | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . |
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
K | E | F | . |
. |
G | P | D | C | V | L | A | V | F | A | E | L |
Query Conservation |   |
. | . | . | . | . | . |   |
|
| . | . |   |
|   |   |
|   |
|
|   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
Y | A | K | I | L | E | D | N | S | I | P | Q | V | K | D | I | I | F | A | I | K | K | T |
Template Known Secondary structure |   |
S | S |  |  |  |  |  | T | T | S |
|
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
304 | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
  |