Job Description P10378 Confidence 100.00% Date Thu Jan 5 11:32:10 GMT 2012 Rank 9 Aligned Residues 492 % Identity 20% Template c3eynB_ PDB info PDB header:ligase Chain: B: PDB Molecule:acyl-coenzyme a synthetase acsm2a; PDBTitle: crystal structure of human acyl-coa synthetase medium-chain2 family member 2a (l64p mutation) in a complex with coa Resolution 1.90 Å

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		28	.	30	.	.	.	.	.			.	.	.	.	40	.	.	.	.	.	.						.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.		.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.
Predicted Secondary structure										.	.												.	.	.	.	.																					.
Query SS confidence										.	.												.	.	.	.	.																					.
Query Sequence		T	D	I	L	T	R	H	A	.	.	A	S	D	S	I	A	V	I	D	G	E	.	.	.	.	.	R	Q	L	S	Y	R	E	L	N	Q	A	A	D	N	L	A	C	S	L	R	.	R	Q	G	I	K	P	G	E	T	A	L	V	Q	L	G	N	V	A	E	L	Y	I	T	F	F	A	L	L	K	L	G	V	A
Query Conservation										.	.												.	.	.	.	.																					.
Alig confidence										.	.												.	.	.	.	.																					.
Template Conservation
Template Sequence		H	W	A	D	M	E	K	A	G	K	R	P	P	S	P	A	L	W	W	V	N	G	K	G	K	E	L	M	W	N	F	R	E	L	S	E	N	S	Q	Q	A	A	N	V	L	S	G	A	C	G	L	Q	R	G	D	R	V	A	V	V	L	P	R	V	P	E	W	W	L	V	I	L	G	C	I	R	A	G	L	I
Template Known Secondary structure									T	T	S	S											S	S	S																							T	T	T				T	T									S														T	T
Template Predicted Secondary structure
Template SS confidence
		53	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.
		100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	V	L	A	L	F	S	H	Q	R	S	E	L	N	A	Y	A	S	Q	I	E	P	A	L	L	I	A	D	R	Q	H	A	L	F	S	G	D	D	F	L	N	T	F	V	T	E	H	S	S	I	R	V	V	Q	L	L	N	D	S	G	E	H	N	L	Q	D	A	I	N	H	P	A	E	D	F	T	A	T	P	S
Query Conservation
Alig confidence																																							.	.	.	.	.
Template Conservation																																							.	.	.	.	.
Template Sequence		F	M	P	G	T	I	Q	M	K	S	T	D	I	L	Y	R	L	Q	M	S	K	A	K	A	I	V	A	G	D	E	V	I	Q	E	V	D	T	.	.	.	.	.	V	A	S	E	C	P	S	L	R	I	K	L	L	V	S	E	K	S	C	D	G	W	L	N	F	K	K	L	L	N	E	A	S	T	T	H	H	C
Template Known Secondary structure							T	T														T		S						T	T	T							.	.	.	.	.		G	G	G		T	T								S	S	S			T	T											S		S
Template Predicted Secondary structure																																							.	.	.	.	.
Template SS confidence
		133	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.						170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.
		180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	A	D	E	V	A	Y	F	Q	L	S	G	G	T	T	G	T	P	K	L	I	P	R	T	H	N	D	Y	Y	Y	S	V	R	R	S	V	E	I	C	Q	F	T	Q	Q	T	R	Y	L	C	A	I	P	A	A	H	N	Y	A	M	S	S	P	G	S	L	G	V	F	L	A	G	G	T	V	V	L	A	A	D	P
Query Conservation
Alig confidence
Template Conservation
Template Sequence		V	E	T	G	S	Q	E	A	S	A	I	Y	F	T	S	G	L	P	K	M	A	E	H	S	Y	S	S	L	G	L	K	A	K	M	D	A	G	W	T	G	L	Q	A	S	D	I	M	W	T	I	S	D	T	G	W	I	L	N	I	L	C	S	L	M	E	P	W	A	L	G	A	C	T	F	V	H	L	L	P	K
Template Known Secondary structure					B	T	T	S																													T	T	T	T	S			T	T									T	T	S							T	T							T									S	S
Template Predicted Secondary structure
Template SS confidence
		208	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.
		260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	A	T	L	C	F	P	L	I	E	K	H	Q	V	N	V	T	A	L	V	P	P	A	V	S	L	W	L	Q	A	L	I	E	G	E	S	R	A	Q	L	A	S	L	K	L	L	Q	V	G	G	A	R	L	S	A	T	L	A	A	R	I	P	A	E	I	G	C	Q	L	Q	Q	V	F	G	M	A	E	G	L	V
Query Conservation
Alig confidence																																						.	.
Template Conservation																																						.	.
Template Sequence		F	D	P	L	V	I	L	K	T	L	S	S	Y	P	I	K	S	M	M	G	A	P	I	V	Y	R	M	L	L	Q	Q	D	L	S	S	Y	.	.	K	F	P	H	L	Q	N	C	V	T	V	G	E	S	L	L	P	E	T	L	E	N	W	R	A	Q	T	G	L	D	I	R	E	S	Y	G	Q	T	E	T	G	L
Template Known Secondary structure														S																	T	S		T	T	S	S	.	.			T	T								S	S															S										T	T	T
Template Predicted Secondary structure																																						.	.
Template SS confidence
		291	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.			.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
		340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.						.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.
Predicted Secondary structure																																																			.	.	.	.	.
Query SS confidence																																																			.	.	.	.	.
Query Sequence		N	Y	T	R	L	D	D	S	A	E	K	I	I	H	T	Q	G	Y	P	M	C	P	D	D	E	V	W	V	A	D	A	E	G	N	P	L	P	Q	G	E	V	G	R	L	M	T	R	G	P	.	.	.	.	.	Y	T	F	R	G	Y	Y	K	S	P	Q	H	N	A	S	A	F	D	A	N	G	F	Y	C	S	G
Query Conservation																																																			.	.	.	.	.
Alig confidence							.	.																																											.	.	.	.	.																			.
Template Conservation							.	.																																																																		.
Template Sequence		T	C	M	V	S	.	.	K	T	M	K	I	K	P	G	Y	M	G	T	A	A	S	C	Y	D	V	Q	I	I	D	D	K	G	N	V	L	P	P	G	T	E	G	D	I	G	I	R	V	K	P	I	R	P	I	G	I	F	S	G	Y	V	D	N	P	D	K	T	A	A	N	I	R	.	G	D	F	W	L	L	G
Template Known Secondary structure							.	.	T	T	S				T	T							T	T								T	T	S		B			T	T										S	S	B			T	T	S					T	T								T			.	T	T
Template Predicted Secondary structure							.	.																																																																		.
Template SS confidence
		369	370	.	.	.			.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.		.	440	.	.	.	.	.
		415	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.								.	.
Predicted Secondary structure																																																																									.	.	.	.	.	.	.
Query SS confidence																																																																									.	.	.	.	.	.	.
Query Sequence		D	L	I	S	I	D	P	E	G	Y	I	T	V	Q	G	R	E	K	D	Q	I	N	R	G	G	E	K	I	A	A	E	E	I	E	N	L	L	L	R	H	P	A	V	I	Y	A	A	L	V	S	M	E	D	E	L	M	G	E	K	S	C	A	Y	L	V	V	K	E	P	L	R	.	.	.	.	.	.	.	A	V
Query Conservation																																																																									.	.	.	.	.	.	.
Alig confidence																																																																									.	.	.	.	.	.	.
Template Conservation
Template Sequence		D	R	G	I	K	D	E	D	G	Y	F	Q	F	M	G	R	A	D	D	I	I	N	S	S	G	Y	R	I	G	P	S	E	V	E	N	A	L	M	E	H	P	A	V	V	E	T	A	V	I	S	S	P	D	P	V	R	G	E	V	V	K	A	F	V	V	L	A	S	Q	F	L	S	H	D	P	E	Q	L	T	K
Template Known Secondary structure								T	T	S								G	G	G					T	T														T	S	T	T												T	T	T												G	G	G	G	G	S
Template Predicted Secondary structure
Template SS confidence
		446	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.
		488	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	V	R	R	F	L	R	E	Q	G	I	A	E	F	K	L	P	D	R	V	E	C	V	D	S	L	P	L	T	A	V	G	K	V	D	K	K	Q	L	R	Q	W	L
Query Conservation
Alig confidence											.
Template Conservation											.
Template Sequence		E	L	Q	Q	H	V	K	S	V	.	T	A	P	Y	K	Y	P	R	K	I	E	F	V	L	N	L	P	K	T	V	T	G	K	I	Q	R	A	K	L	R	D	K	E
Template Known Secondary structure											.	S		G	G	G	S		S						S				B		T	T			B
Template Predicted Secondary structure											.
Template SS confidence
		526	.	.	.	530	.	.	.	.		.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.