|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | H | S | Y | D | Y | D | A | I | V | I | G | S | G | P | G | G | E | G | A | A | M | G | L | V | K | Q | G | A | R | V | A | V | I | E | R | Y | Q | N | V | G | G | G | C | T | H | W | G | T | . |
. |
. |
. |
. |
. |
. |
I | P | S | K | A | L | R | H | A | V | S | R | I | I | E | F | N | Q | N | P | L | Y | S | D |
Query Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|
|   |   |   |   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |
|
|
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | I | D | T | D | Y | D | V | I | V | L | G | T | G | I | T | E | C | I | L | S | G | L | L | S | V | D | G | K | K | V | L | H | I | D | K | Q | D | H | Y | G | G | E | A | A | S | V | T | L | S | Q | L | Y | E | K | F | K | Q | N | P | I | S | K | E | E | R | E | S | K | F | G | K | D | R | D | W | N | V | D | L |
Template Known Secondary structure |   |
|
|
|
| B |
| S |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S | S | S | S |
| G | G | G |
|  |  |
|  |  |  |  |  |  |  |  |
| S | S |
|
|
|  |  |  |  |  |  |  |  |
|
| G | G | G |
|
|  |  | S |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | S | R | L | L | R | S | S | F | A | D | I | L | N | H | A | D | N | V | I | N | Q | Q | T | R | M | R | Q | G | F | Y | E | R | N | H | C | E | I | L | Q | G | N | A | R | F | V | D | E | H | T | L | A | L | D | C | P | D | G | S | V | E | T | L | T | A | E | K | F | V | I | A | C | G | S | R | P | Y | H | P | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | P | K | F | L | M | A | N | G | E | L | T | N | I | L | I | H | T | D | V | T | R | Y | V | D | F | K | Q | V | S | G | S | Y | V | F | K | Q | G | K | I | Y | K | V | P | A | N | E | I | E | A | I | S | S | P | L | M | G | I | F | E | K | R | R | M | K | K | F | L | E | W | I | S | S | Y | K | E | D | D | L | S |
Template Known Secondary structure |   |
S |
|
|
|  |  | T | T | S |  |  |  |  |  |  |  |  |  | T | G | G | G | T |
|
|  |  |  |
|
|
|
|  |  |  |  | T | T |  |  |  |  |
|
| S | S |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| B | T | T | B | G | G |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | V | D | F | T | H | P | R | I | Y | D | S | D | S | I | L | S | M | H | H | E | P | R | H | V | L | I | Y | G | A | G | V | I | G | C | E | Y | A | S | I | F | R | G | M | D | V | K | V | D | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
I | N | T | R | D | R | L | L | A | F | L | D | Q | E | M | S | D |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
T | H | Q | G | L | D | L | D | K | N | T | M | D | E | V | Y | Y | K | F | G | L | G | N | S | T | K | E | F | I | G | H | A | M | A | L | W | T | N | D | D | Y | L | Q | Q | P | A | R | P | S | F | E | R | I | L | L | Y | C | Q | S | V | A | R | Y | G | K | S | P | Y | L | Y | P | M | Y | G | L | G | E | L | P | Q |
Template Known Secondary structure |   |
G | S | T | T |
|
| T | T | T | S | B |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  | T | S |
|
| S | S | S | G | G | G | G | S | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
| S |  |  |  |  | T | T |
| T | T |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
  |
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | |
|
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|  | . | . |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | S | Y | H | F | W | N | S | G | V | V | I | R | H | N | E | E | Y | E | K | I | E | G | C | D | D | G | . |
. |
V | I | M | H | L | K | S | G | K | K | L | K | A | D | C | L | L | Y | A | N | G | R | T | G | N |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   | . | . |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |
|   |   |
|
|   |
|   |   |   |   |
|   |
Template Sequence |   |
G | F | A | R | L | S | A | I | Y | G | G | T | Y | M | L | D | T | P | I | D | E | V | L | Y | K | K | D | T | G | K | F | E | G | V | K | T | K | L | G | T | F | K | A | P | L | V | I | A | D | P | T | Y | F | P | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  | T | T |
|  |  |  |
| S |
|
|
|
|  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  | T | T |  |  |  |  |
| S |
|  |  |  |
| G | G | G |
| G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . |
  |