|   |
20 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
Predicted Secondary structure |   |
 |
|
|
|
|  | . | . | . | . | . |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | R | P | E | N | L | . |
. |
. |
. |
. |
A | Q | Y | I | G | Q | Q | H | L | L | A | A | G | K | P | L | P | R | A | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | A | G | H | L | H | S | M | I | L | W | G | P | P | G | T | G | K | T | T | L | A | E | V | I | A | R | Y | A | N | A | D | V | E | R |
Query Conservation |   |
  |
|
|   |   |
| . | . | . | . | . |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |   |
|
| . | . | . |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
Template Sequence |   |
M | T | P | R | E | I | V | S | E | L | D | Q | H | I | I | G | Q | A | D | A | K | . |
. |
. |
R | A | V | A | I | A | L | R | N | R | W | R | R | M | Q | L | Q | E | P | L | R | H | E | V | T | P | K | N | I | L | M | I | G | P | T | G | V | G | K | T | E | I | A | R | R | L | A | K | L | A | N | A | P | F | I | K |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  | T | T |
|
| S |
|  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | T | T | T | T | T |
|
|
|
|
|  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | |
|
|
. | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 |
  |
  |   |
81 | . | . | . | . | |
|
|
|
|
. | . | . | . | 90 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |
| . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
I | S | A | V | T | . |
. |
. |
. |
. |
S | G | V | K | E | I | R | E | A | I | E | R | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | Q | N | R | N | A | G | R | R | T | I | L | F | V | D | E | V | H | R | F | . |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|
|
|   | . | . | . | . | . |   |   |   |   |
|
|
|   |
|
|   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |
| . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | E | A | T | K | F | T | V | G | K | E | V | D | S | I | I | R | D | L | T | D | S | A | M | K | L | V | R | Q | Q | E | I | A | K | N | R | L | I | D | D | E | A | A | K | L | I | N | P | E | E | L | K | Q | K | A | I | D | A | V | E | Q | N | G | I | V | F | I | D | E | I | D | K | I | C | K | K | G | E | Y | S |
Template Known Secondary structure |   |
 |  | G | G | G | G |
|
|
|
|
| T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
| G | G | G | S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  | T | G | G | G | G | S |
|
| S | S |
| S |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
  |
  |   |
|
|
|
|
|
119 | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 140 | . | |
|
. | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | |
. | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
|
Predicted Secondary structure |   |
. | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  | . | . |
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
| . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
N | K | S | Q | Q | D | A | F | L | P | H | I | E | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | I | T | F | I | G | A | T | . |
. |
T | E | N | P | S | F | E | L | N | S | A | L | L | S | R | A | . |
R | V | Y | L | L | K | S | L | S | T | E | D | I | E | Q | V | L | T | . |
. |
. |
Query Conservation |   |
. | . | . | . | . |   |
|   |   |
|
|   |
|
|   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|
|   |
|
| . | . |
|
|
|
|   |   |   |
|   |   |
|
|   |
|
|   | . |   |   |
|   |
|   |   |
|
|   |
|
|
|   |   |
|
|   | . | . | . |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
Template Sequence |   |
G | A | D | V | S | R | E | G | V | Q | R | D | L | L | P | L | V | E | G | S | T | V | S | T | K | H | G | M | V | K | T | D | H | I | L | F | I | A | S | G | A | F | Q | V | A | R | P | S | D | L | I | P | E | L | Q | G | R | L | P | I | R | V | E | L | T | A | L | S | A | A | D | F | E | R | I | L | T | E | P | H |
Template Known Secondary structure |   |
S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  | T | T |  |  |  |  |
| T | T |
|  |  |  |  |  |  |
|
| S | S |
|
| G | G | G | S |
|  |  |  |  | T | T |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | S | S | T |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
176 | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 210 | . | . | . | . | . | . | |
|
|
|
. | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 |
Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
Q | A | M | E | D | K | T | R | G | Y | G | G | Q | D | I | V | L | P | D | E | T | R | R | A | I | A | E | L | V | . |
. |
. |
. |
. |
. |
. |
. |
N | G | D | A | R | R | A | L | N | T | L | E | . |
. |
. |
. |
M | M | A | D | M | A | E | V | D | D | S | G | K | R | V | L | K | P | E | L | L | T | E | I |
Query Conservation |   |
. | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
| . | . | . | . | . | . | . | . |   |
|
|   |
|   |
|
|
|   |
|
| . | . | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
Template Sequence |   |
A | S | L | T | E | Q | Y | K | A | L | M | A | T | E | G | V | N | I | A | F | T | T | D | A | V | K | K | I | A | E | A | A | F | R | V | N | E | K | T | E | N | I | G | A | R | R | L | H | T | V | M | E | R | L | M | D | K | I | S | F | S | A | S | D | M | N | G | Q | T | V | N | I | D | A | A | Y | V | A | D | A |
Template Known Secondary structure |   |
T |
|  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |
| T | T |
|  |  |  |  |
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . |
  |
  |   |
241 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | G | E | R | S | A | R | F | D |
Query Conservation |   |
|   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
L | G | E | V | V | E | N | E | D |
Template Known Secondary structure |   |
 | T | T | T | T | T |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
  |   |
430 | . | . | . | . | . | . | . | . |
  |