|   |
16 | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | A | R | M | R | P | E | N | L | A | Q | Y | I | G | Q | Q | H | L | L | A | A | G | K | P | L | P | R | A | I | E | A | G | H | L | H | S | M | I | L | W | G | P | P | G | T | G | K | T | T | L | A | E | V | I | A | R | Y | . |
. |
. |
. |
. |
A | N | A | D | V | E | R | I | S | A | V | T | S | G | V | K | E |
Query Conservation |   |
|
|
|
|   |
|
|   |   |
|
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |   | . | . | . | . | . |
|   |   |   |   |
|
|
|
|
|
|   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|
|
|   |   |   |   |   |
|
|
|   |   |   |   |   |   |   | . | . | . |
|   |   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
W | V | E | K | Y | R | P | R | T | L | D | E | V | V | G | Q | D | E | V | I | Q | R | . |
. |
. |
L | K | G | Y | V | E | R | K | N | I | P | H | L | L | F | S | G | P | P | G | T | G | K | T | A | T | A | I | A | L | A | R | D | L | F | G | E | N | W | R | D | N | F | I | E | M | N | A | S | D | E | R | G | I | D |
Template Known Secondary structure |   |
 |  |  |  | T |
|
| S | S | G | G | G |
|
| S |
|  |  |  |  |  |  | . | . | . |  | G | G | G | T | T | T | T |
|
|
|
|  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T |
|  |  |  |  | T | T | S | T | T | S | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  | . | . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | |
|
|
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
  |
  |   |
|
|
|
91 | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
I | R | E | A | I | E | R | A | R | Q | N | R | N | A | G | R | R | T | I | L | F | V | D | E | V | H | R | F | N | K | S | Q | Q | D | A | F | L | P | H | I | E | D | G | T | I | T | F | I | G | A | T | T | E | N | P | S | F | E | L | N | S | A | L | L | S | R | A | R | V | Y | L | L | K | S | L | S | T |
Query Conservation |   |
. | . | . |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |
|   |
|   |   |
|
|   |
|
|   |   |
|
|   |
|   |   |   |
|
|   |
|
|
|
|
|
|   |   |   |
|   |   |
|
|   |
|
|   |   |   |
|   |
|   |   |
|
|   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | V | R | H | K | I | K | E | F | A | R | T | A | P | I | G | G | A | P | F | K | I | I | F | L | D | E | A | D | A | L | T | A | D | A | Q | A | A | L | R | R | T | M | E | M | Y | S | K | S | C | R | F | I | L | S | C | N | Y | V | S | R | I | I | E | P | I | Q | S | R | C | A | V | F | R | F | K | P | V | P | K |
Template Known Secondary structure |   |
T | S | S |  |  |  |  |  |  |  |  | S |
|
| T | T | T |
|
|
|  |  |  |  |  |  | T | G | G | G | S |
|  |  |  |  |  | T | T | G | G | G | T | S | S | S | S | S | S |  |  |  |  |  |  |  | S |
| G | G | G | S |
|  |  |  |  | T | T |
|  |  |  |  |
|
|
|
|
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
168 | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | D | I | E | Q | V | L | T | Q | A | M | E | D | K | T | R | G | Y | G | G | Q | D | I | V | L | P | D | E | T | R | R | A | I | A | E | L | V | N | G | D | A | R | R | A | L | N | T | L | E | M | M | A | D | M | A | E | V | D | D | S | G | K | R | V | L | K | P | E | L | L | T | E | I | A | G | E | R | S | A | R |
Query Conservation |   |
|
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |   |
|
|   |   |
|   |
|
|   |
|   |
|
|
|   |
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
E | A | M | K | K | R | L | L | E | I | C | E | K | E | . |
. |
. |
. |
. |
. |
. |
G | V | K | I | T | E | D | G | L | E | A | L | I | Y | I | S | G | G | D | F | R | K | A | I | N | A | L | Q | G | A | A | A | I | G | E | V | . |
. |
. |
. |
. |
. |
. |
V | D | A | D | T | I | Y | Q | I | T | A | T | A | . |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . | . | . | . | . | . | T |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  | S | S | S | S |
| . | . | . | . | . | . | . | B |
|  |  |  |  |  |  |  | T | T |
|
| . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 220 | . | . | . | . | . | . | |
|
|
  |
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | |
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | |
. |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Query Sequence |   |
F | D | N | K | G | D | R | F | Y | D | L | I | S | A | L | H | K | S | V | R | G | S | A | P | D | A | A | L | Y | W | Y | A | R | I | I | T | A | . |
G | G | D | P | L | Y | V | A | R | R | C | L | A | I | A | S | E | D | V | G | N | A | D | P | R | A | M | Q | V | A | I | A | A | W | D | C | F | T | R | V | . |
G |
Query Conservation |   |
|
|
|   |
|
|   |
|
|
|   |
|
|
|   |   |
|
|
|
|
|
|
|   |
|
|
|
|   |   |
|
|
|   |
|   |   | . |
|
|
|
|   |   |
|   |
|
|
|   |   |   |
|
|
|
|
|
|
|
|   |
|   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   | . |
|
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
R | P | E | E | M | T | E | L | I | Q | T | A | L | K | G | N | F | M | E | A | R | E | L | L | D | R | L | M | V | E | Y | G | M | S | G | E | D | I | V | A | Q | L | F | R | E | I | . |
I | S | M | P | I | K | D | S | L | K | V | Q | L | I | D | K | L | G | E | V | D | F | R | L | T | E |
Template Known Secondary structure |   |
. | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  | S | S |
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
227 | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |
  |   |
326 | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | E | G | E | R | A | I | A | Q | A | I | V | Y | L | A | C | A | P | K |
Query Conservation |   |
  |
|
|   |   |   |   |
|
|   |   |   |   |   |
|
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|   |
|
|   |   |
|   |   |
|   |   |   |   |
|
Template Sequence |   |
G | A | N | E | R | I | Q | L | D | A | Y | L | A | Y | L | S | T | L | A | K |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
299 | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
  |