|   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | |
|
|
. | . | . | . | . | . | . | 70 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | Q | S | V | M | V | V | G | A | A | V | I | D | V | I | A | D | A | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | L | P | W | R | G | C | D | I | E | L | K | Q | Q | S | V | N | V | G | G | C | A | L | N | I | A | V | A | . |
. |
. |
L | K | R | L | G | I | E | A | G |
Query Conservation |   |
  |   |   |   |
|   |
|
|
|   |   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |   | . | . | . |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|
|   |   |
|
|   |   |   |
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |
|
|   |   |
|
|   |
|
|   |   |   |   |
Template Sequence |   |
R | D | G | M | L | V | G | L | G | N | P | L | L | D | I | S | A | V | V | E | K | D | L | L | N | K | Y | D | M | Q | P | N | N | A | I | L | A | E | E | K | H | M | P | M | Y | Q | E | L | I | E | K | Y | Q | A | E | Y | I | A | G | G | S | V | Q | N | S | L | R | V | A | Q | W | I | L | Q | R | P | R | T | A | I |
Template Known Secondary structure |   |
| T | T |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | T | T |
|
| S | S |
|  |  |  |
|
| G | G | G |  |  |  |  |  |  |  |  |  | T | S |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | S |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
72 | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | |
|
|
|
. | . | . | 140 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | A | L | P | L | G | Q | G | V | W | A | E | M | I | R | N | R | M | A | K | E | G | L | I | S | L | I | D | N | A | E | G | D | N | G | W | C | L | A | L | V | E | P | D | G | E | R | T | F | M | S | F | S | G | V | E | N | Q | W | N | R | Q | W | L | A | . |
. |
. |
. |
R | L | T | V | A | P | G | S | L | L | Y |
Query Conservation |   |
  |
|   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
F | F | G | C | V | G | Q | D | E | Y | A | R | I | L | E | E | R | A | T | S | N | G | V | N | V | Q | Y | Q | R | S | A | T | S | P | T | G | T | C | A | V | L | V | T | G | T | Q | R | S | L | C | A | N | L | A | A | A | N | D | F | T | P | E | H | L | R | S | D | G | N | R | A | Y | L | Q | G | A | Q | F | F | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | S | S | S |
|
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
| G | G | G | G | G |
|
| G | G | G | G | G | S |  |  |  |  |  |  |  |  | T |
| S |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
148 | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | |
. | . | . | . | . | . | . | . | 220 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
F | S | G | Y | Q | L | A | S | P | C | G | E | L | L | V | E | W | L | E | E | L | Q | D | V | T | P | F | I | D | F | G | P | R | I | G | D | . |
. |
. |
I | P | D | A | L | L | A | R | I | M | A | C | R | P | L | V | S | L | N | R | Q | E | A | E | I | A | A | E | . |
R | F | A | L | S | A | E | I | T | T | L | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
V | S | G | F | F | F | T | . |
V | S | F | E | S | A | L | S | V | A | K | E | A | A | A | T | G | R | M | F | M | M | N | L | S | A | P | F | V | P | Q | F | Y | K | N | N | L | E | E | I | F | P | Y | V | D | V | L | F | G | N | E | T | E | A | I | A | L | A | K | E | F | N | Y | G | T | E | D | L | R | E | I | G |
Template Known Secondary structure |   |
 |  | G | G | G |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
| S | T |  |  |  |  |  |
|  |  |  |  |  |  |  | G | G | G |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | |
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
224 | . | . | . | . | . | |
|
|
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | Q | W | Q | E | K | . |
. |
. |
. |
. |
. |
F | A | A | P | L | I | V | R | L | D | K | E | G | A | W | Y | F | S | N | D | A | S | G | C | I | P | A | F | P | T | Q | V | V | D | T | I | G | A | G | D | S | H | A | G | G | V | L | A | G | L | A | S | G | L | P | L | A | D | A | V | L | L | G | N | A | V | A | S |
Query Conservation |   |
  |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
Template Sequence |   |
K | R | I | A | A | L | P | K | E | N | G | K | R | K | R | I | V | I | I | T | Q | G | S | D | P | V | L | L | I | E | A | G | T | D | . |
. |
. |
N | V | R | E | F | P | V | Q | K | L | N | G | A | G | D | A | F | V | G | G | F | L | A | Q | L | L | Q | S | R | T | V | D | V | C | I | K | C | G | I | W | A | A | R |
Template Known Secondary structure |   |
 |  |  |  | T | S |
|
| S |
| T | T | S |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T |
| S | . | . | . |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
|
|
. | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
298 | . | 300 | . |
Predicted Secondary structure |   |
 |  |  |  |
Query SS confidence |   |
|
|
|
|
Query Sequence |   |
W | V | V | G |
Query Conservation |   |
  |   |
|   |
Alig confidence |   |
|
|
|
|
Template Conservation |   |
  |   |
|
|
Template Sequence |   |
E | I | I | Q |
Template Known Secondary structure |   |
 |  |  |
|
Template Predicted Secondary structure |   |
 |
|
|
|
Template SS confidence |   |
|
|
|
|
  |   |
329 | 330 | . | . |
  |