|   |
228 | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | A | H | N | L | A | L | S | I | D | E | R | L | Q | A | L | V | Y | R | E | L | N | N | A | V | A | F | N | K | A | E | S | G | S | A | V | L | V | D | V | N | T | G | E | V | L | A | M | A | N | S | P | S | Y | N | P | N | N | L | S | G | T | P | K | E | A | M | R | N | R | T | I | T | D | V | F | E | P | G | S |
Query Conservation |   |
  |
|   |   |
|   |
|
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |
|
|   |
|
|
|   |
|
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |
|
|
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |
|   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
|   |   |
|
|   |
|   |   |
|
|   |   |   |   | . | . | . | . | . | . |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|   |   | . |   |   |   |
|
|
|
Template Sequence |   |
P | G | T | N | V | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | E | D | Y | S | T | F | F | D | K | F | S | A | S | . |
G | G | F | V | L | F | N | S | N | R | K | K | Y | T | I | . |
. |
. |
. |
. |
. |
Y | N | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | E | S | T | S | . |
R | F | A | P | A | S |
Template Known Secondary structure |   |
S | S |
|  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  | T | T | T |  |  | . |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  | . | . | . | . | . | . |  |
|  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  | S | . |
| B |
|
| G | G |
Template Predicted Secondary structure |   |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . | . |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
354 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | |
. | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 390 | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | |
. | . | . | 400 | . | . |
  |
  |   |
308 | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | V | K | P | M | V | V | M | T | A | L | Q | R | G | V | V | R | E | N | S | V | L | N | T | I | P | Y | R | I | N | G | H | E | I | K | D | V | A | R | Y | S | E | L | T | L | T | G | V | L | Q | K | S | S | N | V | G | V | S | K | L | A | L | A | M | P | S | S | A | L | V | D | T | Y | S | R | F | G | L | G | K |
Query Conservation |   |
|
|
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|
|   |
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
Template Sequence |   |
T | Y | K | V | F | S | A | L | L | A | L | E | S | G | I | I | T | K | N | D | S | H | M | T | W | D | . |
. |
. |
. |
G | T | Q | Y | P | Y | K | E | W | N | Q | D | Q | D | L | F | S | A | M | S | S | S | T | T | W | Y | F | Q | K | L | D | R | Q | I | G | E | D | H | L | R | H | Y | L | K | S | I | H | Y | G | N |
Template Known Secondary structure |   |
G | G |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
| S | S |
|
|
| B |
|
|
| . | . | . | . |
|
|
|
| S | S | T | T | T | S | S |
| B |
|  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
| . | . | . | . |
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
403 | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | |
|
|
|
. | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
  |
  |   |
388 | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | |
. | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | T | N | L | G | L | V | G | E | R | S | G | L | Y | P | Q | K | Q | R | W | S | D | I | E | R | A | T | F | S | F | G | Y | G | . |
L | M | V | T | P | L | Q | L | A | R | V | Y | A | T | I | G | S | Y | G | I | Y | R | P | L | S | I | T | K | V | D | P | P | V | P | G | E | R | V | F | P | E | S | I | V | R | T |
Query Conservation |   |
  |
|
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
| . |   |   |
|
|
|
|
|
|
|   |   |   |
|   |
|
|
|   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |
|
|
|
|
|   |
|   |   |   |   |   |
|
|
|   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |
Template Sequence |   |
E | D | F | S | V | P | A | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | W | L | D | G | S | L | Q | I | S | P | L | E | Q | V | N | I | L | K | K | F | Y | D | N | E | F | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | K | Q | S | N | I | E | T |
Template Known Secondary structure |   |
|
|
| S |
| T | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | T | T | T | S | S | S | S |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
479 | 480 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 520 | . |
  |
  |   |
467 | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | V | H | M | M | E | S | V | A | L | P | G | G | G | G | V | K | A | A | I | K | G | Y | R | I | A | I | K | T | G | T | A | K | K | V | G | P | D | G | R | Y | I | N | K | Y | I | A | Y | T | A | G | V | A | P | A | S | Q | P | R | F | A | L | V | V | V | I | N | D | P | Q | A | G | K | Y | Y | G | G | A | V | S |
Query Conservation |   |
|   |   |   |
|   |   |
|
|   |   |   |
|
|
|   |   |
|   |   |   |
|   |   |
|
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |
|   |   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|
|
|
|
|
|
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |
|
|
|   |
|   |   |   |   |   | . | . | . |   |   |   |   |   |
|
Template Sequence |   |
V | K | D | S | I | R | L | E | E | S | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | V | L | S | G | K | T | G | T | S | V | I | N | . |
. |
. |
. |
. |
. |
G | E | L | H | A | G | W | F | I | G | Y | V | E | T | A | D | N | T | F | F | F | A | V | H | I | Q | G | E | K | R | . |
. |
. |
A | A | G | S | S | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | . | . | . | T |  |  |  |  |  |  |  |  |  |  |  |
| S | . | . | . | . | . | . | S | S |
|  |  |  |  |  |  |  |  |  |  |
| S | S |
|  |  |  |  |  |  |  |  |  |  | S |
| S | . | . | . |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
522 | . | . | . | . | . | . | . | 530 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 540 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | |
|
|
. | . | . | 580 | . | . |
  |
  |   |
547 | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | P | V | F | G | A | I | M | G | G | V | L | R | T | M | N | I | E | P |
Query Conservation |   |
|
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |
|   |   |   | . | . | . | . |
|   |
|   |
|
Template Sequence |   |
A | E | I | A | L | S | I | L | D | K | . |
. |
. |
. |
K | G | I | Y | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . | T | T | S |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
583 | . | . | . | . | . | . | 590 | . | . | |
|
|
|
. | . | . | . | . |
  |