|   |
29 | 30 | . | . | . | . | . | . | . | . | . | |
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | |
. | 100 | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  | . |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Query Sequence |   |
H | I | E | L | I | A | S | E | N | Y | T | . |
S | P | R | V | M | Q | A | Q | G | S | Q | L | T | N | . |
. |
K | Y | A | E | G | Y | P | G | K | R | Y | Y | G | G | C | E | Y | V | D | I | V | E | Q | L | A | I | D | R | A | K | E | L | F | G | A | D | Y | A | N | V | Q | P | H | S | G | . |
S | Q | A | N | F | A |
Query Conservation |   |
  |
|   |
|   |   |   |   |
|   |   | . |
|
|   |
|   |   |
|   |   |   |   |   |   |   | . | . |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |
|
| . |
|   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|
|   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |
|   |
|
|   |   |
Template Sequence |   |
I | V | N | F | S | T | T | V | W | T | D | G | D | D | H | L | E | K | H | L | V | E | N | L | N | C | I | R | H | Y | P | E | P | D | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | L | R | Q | X | L | A | K | R | N | S | V | D | N | N | A | I | L | V | T | N | G | P | T | A | A | F | Y | Q |
Template Known Secondary structure |   |
|  |  |
| S |
|
| S |
|
|
|
|
|
|  |  |  |  |  |  |  |  | T | G | G | G | G | G | S |
|
|
| T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  | T | T |
|
| G | G | G |  |  |  |  | S |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
17 | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | Y | T | A | L | L | E | P | G | D | T | V | L | G | M | N | L | A | H | G | G | H | L | T | H | G | S | P | V | N | F | S | G | K | L | Y | N | I | V | P | Y | G | I | D | A | T | G | H | I | D | Y | A | D | L | E | K | Q | A | K | E | H | K | P | K | M | I | I | G | G | F | S | A | Y | S | G | V | V | D | W | A |
Query Conservation |   |
  |
|   |
|
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
| . | . |   |
|
|   |
|
|
|   |   |
|   |
|   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |
Template Sequence |   |
I | A | Q | A | F | . |
. |
R | G | S | R | S | L | I | A | I | P | S | F | A | . |
. |
. |
E | Y | E | D | A | C | R | X | Y | E | H | E | V | C | F | Y | P | S | N | E | D | I | G | E | A | D | F | . |
. |
. |
. |
. |
. |
. |
. |
S | N | X | D | F | C | W | L | C | N | P | N | N | P | D | G | R | L | L | Q | R | T |
Template Known Secondary structure |   |
 |  |  |  | T | . | . | T | T |
|  |  |  |  |  |  | S |
|
|  | . | . | . |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | T | T | S |
| G | G | G | S |
|
| . | . | . | . | . | . | . | . | T | T |
| S |  |  |  |  |  | S | S |
| T | T | T |
|
|
|
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
| . | . |
|
|
|  |  |  |  |  |
|
|
|
|  | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
83 | . | . | . | . | |
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | |
|
|
. | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
  |
  |   |
185 | . | . | . | . | |
190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
. | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
Predicted Secondary structure |   |
 |  |  |  |  | . |  |  |  |
|
|
|  |  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | M | R | E | I | . |
A | D | S | I | G | A | Y | L | F | V | D | M | A | H | V | A | G | L | V | A | A | G | V | Y | P | N | P | V | P | . |
. |
H | A | H | V | V | T | T | T | T | H | K | T | L | A | G | P | R | G | G | L | I | L | A | K | G | G | S | E | E | L | Y | K | K | L | N | S | A | V | F | P | G | G | Q |
Query Conservation |   |
  |
|   |   |
| . |
|   |   |   |
|   |   |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |
|   |   |   |   |
|   |   |
|   |
|   |
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
E | I | L | R | L | L | N | D | H | P | D | T | T | F | V | L | D | Q | S | Y | V | S | F | T | T | E | E | V | I | R | P | A | D | I | K | G | R | K | N | L | V | X | V | Y | S | F | S | H | A | Y | . |
G | I | P | G | L | R | I | G | Y | I | V | A | N | K | D | F | X | K | R | V | A | A | F | S | T | P | W | A | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |
| T | T | G | G | G |
| S | S |
|
|
|
| G | G | G | G | T | T |
| S | S |  |  |  |  |  |  | S | T | T | T | S | . | S |
| G | G | G |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  | T | T |
|
| T | T |
| S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
| . |
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
  |
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | G | P | L | M | H | V | I | A | G | K | A | V | A | L | K | E | A | M | E | P | E | F | K | T | Y | Q | Q | Q | V | A | K | N | A | K | A | M | V | E | V | F | L | E | R | G | Y | K | V | V | S | G | G | T | D | N | H | L | F | L | V | D | L | V | D | K | N | L | T | G | K | E | A | D | A | A | L | G | R | A | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Template Sequence |   |
N | . |
. |
. |
. |
. |
A | L | A | I | E | A | A | K | F | I | L | I | H | P | A | Q | F | T | L | P | I | R | K | W | Q | R | N | T | V | D | F | I | T | A | L | N | R | L | D | G | V | E | V | H | P | S | G | . |
T | T | F | F | L | L | R | L | . |
K | K | G | T | A | A | E | L | K | K | Y | X | L | E | E | Y | N |
Template Known Secondary structure |   |
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |  |  |  |
|
|
| S | . | S | S |  |  |  |  |  |  | . | S | S | S |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
| . |
|
|  |  |  |  |  |
| . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
229 | |
|
|
|
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
. | . | . | 280 | . | . | . | . | |
. | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
  |
  |   |
342 | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | T | V | N | K | N | S | V | P | N | D | P | K | S | P | F | V | T | S | G | I | R | V | G | T | P | A | I | T | R | R | G | F | K | E | A | E | A | K | E | L | A | G | W | M | C | D | V | L | D | S | I |
Query Conservation |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
| . | . | . | . |   |   |
|   |   |
|   |   |   |   |   |   |   |
|
|
|
|   |   | . | . | . | . | . | . | . |   |   |
|
|   |
|   |
|   |   |   |
|   |   |   |
|   |
|
|
Template Sequence |   |
X | L | I | . |
. |
. |
. |
R | D | A | S | N | F | R | G | L | D | E | S | Y | V | R | I | T | T | Q | . |
. |
. |
. |
. |
. |
. |
R | P | A | Q | N | Q | L | F | I | K | A | L | E | T | F | L | E | K | Y |
Template Known Secondary structure |   |
 |  |
| . | . | . | . |  |  |
| T | T | S | T | T |
|
| T | T |  |  |  |  |  |
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|  |  | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
302 | . | . | |
|
|
|
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . |
  |