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Job DescriptionP0A825
Confidence99.97%DateThu Jan 5 11:06:42 GMT 2012
Rank57Aligned Residues369
% Identity15%Templatec2hzpA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase
Resolution2.00 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   4.....10.........20....... ..30.. .......40.........50........
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Query Sequence  REMNIADYDAELWQAMEQEKVRQE. . . . . . . . . . . . . . . . . . . . . . . . EHIEL. IASENYTSPRVMQAQGSQLTNKYAEG
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Template Sequence  AELKCHPTDERVALHLDEEDKLRHFREFYIPKIQDLPPVDLSLVNKDENAIYFLGNSLGLQPKMVKTYLEEEL. DKWAKI
Template Known Secondary structure  TS
TTS
TTGGGG

B

BGGGSTT

GGGS
TT
B

BTTTS

B
TT.
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   18.20.........30.........40.........50.........60.........70.........80.........90 ......
 
   5960.........70.........80.........90........ .100.........110.. .......120.........130 ...
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Query Sequence  YPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSG. SQANFAVYTALLEP. . . GDTVLGMNLAHGGHLTHG. SPV
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Template Sequence  AAYGHEVGKRPWITGDES. IVGLMKDIVGANEKEIALMNALTVNLHLLMLSFFKPTPKRYKILLEAKAFPSDHYAIESQL
Template Known Secondary structure  GGGGGTSSSS
GGGTTTT.TGGGGT

GGG
S




SSS
TT

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   98.100.........110..... ....120.........130.........140.........150.........160.........170......
 
   134.....140. ........150.........160... ......170... ......180.........190.........200......
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Query Sequence  NFSGKLYN. . . IVPYGIDATGHIDYADLEKQAK. . . EHKPKMIIGG. FSAYSGVVDWAKMREIADSIGAYLFVDMAHVAG
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Template Sequence  QLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIAVILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVG
Template Known Secondary structure  TT




TT
SS

GGGSB
TTT
BB

TT

TTTTT
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   177..180.........190.........200.........210.........220.........230.........240.........250......
 
   207..210.........220.........230...... ...240.........250 .........260...
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Query Sequence  LVAAGVYPNPVPHAHVVTTTTHKTLAGPRG. . GLILAKGGSEELYK. . . . . . . . . . . . . . . . . . . . . KLNSAVFPGGQGG
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Template Sequence  NVELYLHDW. . . GVDFACWCSYKYLNAGAGGIAGAFIHEKHAHTIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISN
Template Known Secondary structure  TS


...T


SSSTT


TT



GGGTTTS

SS

GGGB
TT

S


B
SSGGGG

S
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   257..260..... ....270.........280.........290.........300.........310.........320.........330...
 
   264.....270.........280.........290.........300..... ....310.........320.........330.........340
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Query Sequence  PLMHVIAGKAVALKEAMEPEFKTYQQQVAKNAKAMVEVFLER. . . GYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRA
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Template Conservation         

 
 
  
   
   
      
   
   
      
  
  
     
   
          
   
   
Template Sequence  PPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNYGKVVNIITPSHVEERGCQLTITFSVPNKDVFQELEKR
Template Known Secondary structure 







S
SSGGGB
S


TT

TT
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   334.....340.........350.........360.........370.........380.........390.........400.........410...
 
   341........350.........360...... ...370.........380.........390.
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Query Sequence  NITVNKNSVPNDPKSPFVTSGIRVGT. PAITRRGFKEAEAKELAGWMCDVLD
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Template Sequence  GVVCDKR. . . . . . . . . . NPNGIRVAPVPLYNS. . . . FHDVYKFTNLLTSILD
Template Known Secondary structure  T
..........TTTB

TTT

....T
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   422...... .430.........440... ......450.........
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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