Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	F	G	K	L	S	L	D	A	V	P	F	H	E	P	I	V	M	V	T	I	A	G	I	I	L	G	G	L	A	L	V	G	L	I	T	Y	F	G	K	W	T	Y	L	W	K	E	W	L	T	S	V	D	H	K	R	L	G	I	M
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Y	I	I	V	A	I	V	M	L	L	R	G	F	A	D	A	I	M	M	R	S	Q	Q	A	L	A	S	A	G	E	A	G	F	L	P	P	H	H	Y	D	Q	I	F	T	A	H	G	V	I	M	I	F	F	V	A	M	P	F	V	I
Secondary structure
SS confidence
Disorder																															?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180
Sequence		G	L	M	N	L	V	V	P	L	Q	I	G	A	R	D	V	A	F	P	F	L	N	N	L	S	F	W	F	T	V	V	G	V	I	L	V	N	V	S	L	G	V	G	E	F	A	Q	T	G	W	L	A	Y	P	P	L	S	G	I	E
Secondary structure
SS confidence
Disorder												?	?	?	?	?	?	?																																									?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240
Sequence		Y	S	P	G	V	G	V	D	Y	W	I	W	S	L	Q	L	S	G	I	G	T	T	L	T	G	I	N	F	F	V	T	I	L	K	M	R	A	P	G	M	T	M	F	K	M	P	V	F	T	W	A	S	L	C	A	N	V	L	I	I
Secondary structure
SS confidence
Disorder		?	?	?																																			?	?	?		?
Disorder confidence
		.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300
Sequence		A	S	F	P	I	L	T	V	T	V	A	L	L	T	L	D	R	Y	L	G	T	H	F	F	T	N	D	M	G	G	N	M	M	M	Y	I	N	L	I	W	A	W	G	H	P	E	V	Y	I	L	I	L	P	V	F	G	V	F	S	E
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360
Sequence		I	A	A	T	F	S	R	K	R	L	F	G	Y	T	S	L	V	W	A	T	V	C	I	T	V	L	S	F	I	V	W	L	H	H	F	F	T	M	G	A	G	A	N	V	N	A	F	F	G	I	T	T	M	I	I	A	I	P	T	G
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420
Sequence		V	K	I	F	N	W	L	F	T	M	Y	Q	G	R	I	V	F	H	S	A	M	L	W	T	I	G	F	I	V	T	F	S	V	G	G	M	T	G	V	L	L	A	V	P	G	A	D	F	V	L	H	N	S	L	F	L	I	A	H	F
Secondary structure
SS confidence
Disorder														?	?	?	?	?																									?
Disorder confidence
		.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480
Sequence		H	N	V	I	I	G	G	V	V	F	G	C	F	A	G	M	T	Y	W	W	P	K	A	F	G	F	K	L	N	E	T	W	G	K	R	A	F	W	F	W	I	I	G	F	F	V	A	F	M	P	L	Y	A	L	G	F	M	G	M	T
Secondary structure
SS confidence
Disorder																										?
Disorder confidence
		.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Sequence		R	R	L	S	Q	Q	I	D	P	Q	F	H	T	M	L	M	I	A	A	S	G	A	V	L	I	A	L	G	I	L	C	L	V	I	Q	M	Y	V	S	I	R	D	R	D	Q	N	R	D	L	T	G	D	P	W	G	G	R	T	L	E
Secondary structure
SS confidence
Disorder																																												?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.	.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600
Sequence		W	A	T	S	S	P	P	P	F	Y	N	F	A	V	V	P	H	V	H	E	R	D	A	F	W	E	M	K	E	K	G	E	A	Y	K	K	P	D	H	Y	E	E	I	H	M	P	K	N	S	G	A	G	I	V	I	A	A	F	S	T
Secondary structure
SS confidence
Disorder																														?	?	?	?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	610	.	.	.	.	.	.	.	.	.	620	.	.	.	.	.	.	.	.	.	630	.	.	.	.	.	.	.	.	.	640	.	.	.	.	.	.	.	.	.	650	.	.	.	.	.	.	.	.	.	660
Sequence		I	F	G	F	A	M	I	W	H	I	W	W	L	A	I	V	G	F	A	G	M	I	I	T	W	I	V	K	S	F	D	E	D	V	D	Y	Y	V	P	V	A	E	I	E	K	L	E	N	Q	H	F	D	E	I	T	K	A	G	L	K
Secondary structure
SS confidence
Disorder																																																									?	?	?	?	?
Disorder confidence
		.	.	.
Sequence		N	G	N
Secondary structure
SS confidence
Disorder		?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1m56 chain G Region: 42 - 560 Aligned: 513 Modelled: 519 Confidence: 100.0% Identity: 38% PDB header:oxidoreductase Chain: G: PDB Molecule:cytochrome c oxidase; PDBTitle: structure of cytochrome c oxidase from rhodobactor2 sphaeroides (wild type) Phyre2 PDB 3dtu chain A domain 1 Region: 42 - 552 Aligned: 508 Modelled: 511 Confidence: 100.0% Identity: 38% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 1v54 chain A Region: 45 - 561 Aligned: 510 Modelled: 517 Confidence: 100.0% Identity: 39% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 1ar1 chain A Region: 45 - 554 Aligned: 505 Modelled: 510 Confidence: 100.0% Identity: 39% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 1fft chain A Region: 52 - 552 Aligned: 501 Modelled: 501 Confidence: 100.0% Identity: 100% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 1fft chain F Region: 52 - 552 Aligned: 501 Modelled: 501 Confidence: 100.0% Identity: 100% PDB header:oxidoreductase Chain: F: PDB Molecule:ubiquinol oxidase; PDBTitle: the structure of ubiquinol oxidase from escherichia coli Phyre2 PDB 3eh4 chain A Region: 47 - 533 Aligned: 470 Modelled: 487 Confidence: 100.0% Identity: 19% PDB header:oxidoreductase Chain: A: PDB Molecule:cytochrome c oxidase subunit 1; PDBTitle: structure of the reduced form of cytochrome ba3 oxidase from thermus2 thermophilus Phyre2 PDB 1xme chain A domain 1 Region: 53 - 533 Aligned: 464 Modelled: 481 Confidence: 100.0% Identity: 20% Fold: Cytochrome c oxidase subunit I-like Superfamily: Cytochrome c oxidase subunit I-like Family: Cytochrome c oxidase subunit I-like Phyre2 PDB 3mk7 chain K Region: 50 - 531 Aligned: 449 Modelled: 466 Confidence: 100.0% Identity: 14% PDB header:oxidoreductase Chain: K: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit n; PDBTitle: the structure of cbb3 cytochrome oxidase Phyre2 PDB 3o0r chain B Region: 53 - 516 Aligned: 428 Modelled: 437 Confidence: 100.0% Identity: 15% PDB header:immune system/oxidoreductase Chain: B: PDB Molecule:nitric oxide reductase subunit b; PDBTitle: crystal structure of nitric oxide reductase from pseudomonas2 aeruginosa in complex with antibody fragment Phyre2 PDB 1m56 chain C Region: 578 - 660 Aligned: 70 Modelled: 83 Confidence: 95.2% Identity: 11% Fold: Cytochrome c oxidase subunit III-like Superfamily: Cytochrome c oxidase subunit III-like Family: Cytochrome c oxidase subunit III-like Phyre2 PDB 1v54 chain C Region: 579 - 645 Aligned: 67 Modelled: 67 Confidence: 94.3% Identity: 10% Fold: Cytochrome c oxidase subunit III-like Superfamily: Cytochrome c oxidase subunit III-like Family: Cytochrome c oxidase subunit III-like Phyre2 PDB 1qle chain C Region: 579 - 637 Aligned: 59 Modelled: 59 Confidence: 93.8% Identity: 10% Fold: Cytochrome c oxidase subunit III-like Superfamily: Cytochrome c oxidase subunit III-like Family: Cytochrome c oxidase subunit III-like Phyre2 PDB 1fft chain B domain 2 Region: 492 - 540 Aligned: 49 Modelled: 49 Confidence: 33.9% Identity: 16% Fold: Transmembrane helix hairpin Superfamily: Cytochrome c oxidase subunit II-like, transmembrane region Family: Cytochrome c oxidase subunit II-like, transmembrane region Phyre2 PDB 3mk7 chain F Region: 503 - 566 Aligned: 51 Modelled: 64 Confidence: 17.8% Identity: 14% PDB header:oxidoreductase Chain: F: PDB Molecule:cytochrome c oxidase, cbb3-type, subunit p; PDBTitle: the structure of cbb3 cytochrome oxidase Phyre2 PDB 3chx chain G Region: 616 - 645 Aligned: 30 Modelled: 30 Confidence: 16.4% Identity: 23% PDB header:membrane protein Chain: G: PDB Molecule:pmoc; PDBTitle: crystal structure of methylosinus trichosporium ob3b2 particulate methane monooxygenase (pmmo) Phyre2 PDB 1jau chain A Region: 40 - 53 Aligned: 13 Modelled: 14 Confidence: 16.4% Identity: 38% PDB header:viral protein Chain: A: PDB Molecule:transmembrane glycoprotein (gp41); PDBTitle: nmr solution structure of the trp-rich peptide of hiv gp412 bound to dpc micelles Phyre2 PDB 2knc chain A Region: 493 - 532 Aligned: 38 Modelled: 40 Confidence: 13.5% Identity: 11% PDB header:cell adhesion Chain: A: PDB Molecule:integrin alpha-iib; PDBTitle: platelet integrin alfaiib-beta3 transmembrane-cytoplasmic2 heterocomplex Phyre2 PDB 2hf5 chain A domain 1 Region: 626 - 645 Aligned: 20 Modelled: 20 Confidence: 12.3% Identity: 30% Fold: EF Hand-like Superfamily: EF-hand Family: Calmodulin-like Phyre2 PDB 1l9b chain H domain 2 Region: 132 - 154 Aligned: 21 Modelled: 23 Confidence: 11.9% Identity: 43% Fold: Single transmembrane helix Superfamily: Photosystem II reaction centre subunit H, transmembrane region Family: Photosystem II reaction centre subunit H, transmembrane region Phyre2 1 c1m56G_ 2 d3dtua1 3 d1v54a_ 4 d1ar1a_ 5 d1ffta_ 6 c1fftF_ 7 c3eh4A_ 8 d1xmea1 9 c3mk7K_ 10 c3o0rB_ 11 d1m56c_ 12 d1v54c_ 13 d1qlec_ 14 d1fftb2 15 c3mk7F_ 16 c3chxG_ 17 c1jauA_ 18 c2kncA_ 19 d2hf5a1 20 d1l9bh2 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55