|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | Q | S | V | A | N | L | V | D | M | R | D | V | S | F | T | R | G | N | R | C | I | F | D | N | I | S | L | T | V | P | R | G | K | I | T | A | I | M | G | P | S | G | I | G | K | T | T | L | L | R | L | I | G | G | Q | I | A | P | D | H | G | E | I | L | F | D | G | E | N | I | P | A | M | S | R | S | R | L | Y |
Query Conservation |   |
  |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |
|
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |
|   |   |   |   |   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
D | V | E | R | E | T | L | V | E | Y | P | R | L | V | K | D | Y | G | S | F | K | . |
L | E | V | E | P | G | E | I | R | K | G | E | V | I | G | I | V | G | P | N | G | I | G | K | T | T | F | V | K | M | L | A | G | V | E | E | P | T | E | G | K | V | E | W | D | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
| S | S |
|  | . |  |  |  |
|
|  |  |  |  | T | T |
|  |  |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  | T | S | S |
|
| S | B | S |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|  |  | . |  |  |  |  |
|
|  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | |
. | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | V | R | K | R | M | S | M | L | F | Q | S | G | A | L | F | T | D | M | N | V | F | D | N | V | A | Y | P | L | R | E | H | T | Q | L | P | A | P | L | L | H | S | T | V | M | M | K | L | E | A | V | G | L | R | G | A | A | K | L | M | P | S | E | L | S | G | G | M | A | R | R | A | A | L | A | R | A | I | A | L |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |
|
|   |
|
|   |
|
|   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
V | A | Y | K | P | Q | Y | I | K | A | E | Y | E | G | T | V | Y | E | L | L | S | K | I | D | S | S | K | L | N | S | N | . |
. |
. |
. |
. |
F | Y | K | T | E | L | L | K | P | L | G | I | I | D | L | Y | D | R | N | V | E | D | L | S | G | G | E | L | Q | R | V | A | I | A | A | T | L | L | R |
Template Known Secondary structure |   |
. | . | . | . | . |  |  |  |  |
| S | S |
|
|
|
|
| S | S | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  | . | . | . | . | . |  |  |  |  |  | T |  |  |  |  | T |
| T | T | T | T | T | S | B | G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
Template Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
405 | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . |
  |
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | . | . |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | P | D | L | I | M | F | D | E | P | F | V | G | Q | D | P | I | T | M | G | V | L | V | K | L | I | S | E | L | N | S | A | L | G | V | T | C | V | V | V | S | H | D | V | P | E | V | L | S | I | A | D | H | A | W | I | L | A | . |
. |
D | K | K | I | V | A | H | G | S | A | Q | A | L | Q | A | N | P | D | P | R |
Query Conservation |   |
  |
|   |
|
|
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |
|
|
|   |
|
|   | . | . |   |
|   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|
|
|
|
|
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
D | A | D | I | Y | L | L | D | E | P | S | A | Y | L | D | V | E | Q | R | L | A | V | S | R | A | I | R | H | L | M | E | K | N | E | K | T | A | L | V | V | E | H | D | V | L | M | I | D | Y | V | S | D | R | L | I | V | F | E | G | E | P | G | R | H | G | R | A | L | P | P | M | G | M | R | E | G | M | N | R | F |
Template Known Secondary structure |   |
|
| S |  |  |  |  |  |
| T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
| S |
|  |  |  |  |  |  |  |
| S |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
475 | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . |
  |
  |   |
240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | R | Q | F | L | D | G | I | A | D | G | P | V | P | F | R | Y | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|
|   |
Template Sequence |   |
L | A | S | V | G | I | T | F | R | R | D | P | D | S | G | R | P | R |
Template Known Secondary structure |   |
 | T | T | T | T |
|
|  |  |  |
| T | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
555 | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . |
  |