|   |
59 | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
|
|
. | . | . | . | . | . | . | . | 80 | |
|
. | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |
|
| . | . | . |
|  |  |  |
|
|
|
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | E | T | T | L | F | N | E | K | L | S | M | . |
. |
. |
P | V | A | L | A | P | V | G | L | . |
. |
C | G | M | Y | A | R | R | G | E | V | Q | A | A | K | A | A | D | A | H | G | I | P | F | T | L | S | T | V | S | V | C | P | I | E | E | V | A | P | A | I | K | R | P | M | W | F | Q | L | Y | V | L | R | D |
Query Conservation |   |
|
|
|
|   |
|
|
|   |   |   |   |   | . | . | . |
|
|   |
|
|
|
|   |   | . | . |   |   |   |   |   |   |   |   |
|   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |
|   |   |   |   |
|
|   |   |   |
|   |   |
|
|
|
|
|
|   |   |
|
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |
|
|
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |
Template Sequence |   |
N | K | I | V | K | I | G | N | I | D | V | A | N | D | K | P | F | V | L | F | G | G | X | N | V | L | E | S | R | D | X | A | X | Q | V | C | E | A | Y | V | K | V | T | E | K | L | G | V | P | Y | V | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | A | S | F | D | K | A | N |
Template Known Secondary structure |   |
|
|
|  |  |  | T | T |  |  |  |
| T | T | S |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  | S |
|
| T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 60 | . | . |
  |
  |   |
134 | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
Predicted Secondary structure |   |
 | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | F | M | R | N | A | L | E | R | A | K | A | A | G | C | S | T | L | V | F | T | V | D | M | P | T | P | G | A | R | Y | R | D | A | H | S | G | M | S | G | P | N | A | A | M | R | R | Y | L | Q | A | V | T | H | P | Q | W | A | W | D | V | G | L | N | G | R | P |
Query Conservation |   |
  | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
R | S | S | I | H | S | Y | R | G | P | G | X | E | E | G | L | K | I | F | Q | E | L | K | D | T | F | G | V | K | I | I | T | D | V | H | E | I | Y | Q | C | Q | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
| S | S | T | T | S |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
| S | G | G | G |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
63 | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | |
|
. | . | . | . | . | 260 | . | . | . | . | . | |
|
|
|
. | . | . | . | 270 | . | . | |
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
H | D | L | G | N | I | S | A | Y | L | G | K | P | T | G | L | E | D | Y | I | G | W | L | G | N | N | F | D | P | S | I | S | W | K | D | L | E | W | I | R | D | F | W | D | G | P | M | V | I | K | G | I | L | . |
. |
D | P | E | D | A | R | D | A | V | R | F | . |
. |
. |
. |
G | A | D | G | I | V | V | . |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|
|
|
|
|
|
|   | . | . |   |   |
|
|
|   |   |
|   |   |   | . | . | . | . |
|
|
|   |
|   |
| . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |
|
|
|
|   |   |   |   |
|   |   |
|
|   |   |
|
|   | . |   |
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |
|   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | A | D | V | V | D | I | I | Q | L | P | A | F | L | A | R | Q | T | D | L | V | E | A | X | A | K | . |
T | G | A | V | I | N | V | K | K | P | Q | F | L | S | P | S | Q | X | G | N | I | V | E | K | I | E | E | C | G | N | D | K | I | I | L | C | D | R |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  | T | T |
| S |  |  |  |  |
| G | G | G | T | T |
|  |  |  |  |  |  |  |  |  | . | T | T |
|  |  |  |  |  |
|
| T | T | S |
| G | G | G |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . |
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
  |
  |   |
|
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
|
|
|
. | . | . | 310 | . | . | . | . | . | . | . | |
. | . | 320 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  | . |  |  |  |
|
|
|
|  |  |  |  |
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
S | N | H | G | G | R | Q | L | D | G | V | L | S | S | A | R | A | L | P | A | I | A | D | A | V | K | G | D | I | A | I | L | A | D | . |
. |
. |
. |
S | G | I | R | N | G | L | D | V | V | R | . |
M | I | A | L | G | A | D | T | V | L | L |
Query Conservation |   |
. |
|
|
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |
|   |
|
|   |
| . | . | . | . |
|
|
|
|   |
|   |
|
|   |
| . |
|
|
|
|
|
|   |
|
|   |
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |   |
| . | . | . | . |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |
|
|
Template Sequence |   |
G | T | N | F | G | Y | D | N | L | I | V | D | X | L | G | F | S | V | X | . |
. |
. |
. |
K | K | A | S | K | G | S | P | V | I | F | D | V | T | H | S | L | Q | R | A | Q | V | T | E | L | A | R | S | G | L | A | V | G | I | A | G | L | F | L |
Template Known Secondary structure |   |
|  |  |
| S | T | T |
|  |  |
|
| T | T |  |  |  |  |  | . | . | . | . |  |  |  | T | T | S |
|
|  |  |  |  |  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | |
|
|
|
. | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . |
  |