Job Description P33232 Confidence 100.00% Date Thu Jan 5 11:51:32 GMT 2012 Rank 29 Aligned Residues 310 % Identity 20% Template c2fptA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors Resolution 2.40 Å

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		10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	A	A	A	Q	R	I	L	P	P	F	L	F	H	Y	M	D	G	G	A	Y	S	E	Y	T	L	R	R	N	V	E	D	L	S	E	V	A	L	R	Q	R	I	L	K	N	M	S	D	L	S	L	E	T	T	L	F	N	E	K	L	S	M	P	V	A	L	A	P	V	G	L	C	G	M	Y	A	R	R	G	E
Query Conservation
Alig confidence																												.	.	.	.	.											.	.	.	.																								.	.	.	.	.	.	.
Template Conservation																												.	.	.	.	.											.	.	.	.																								.	.	.	.	.	.	.
Template Sequence		E	R	F	Y	A	E	H	L	M	P	T	L	Q	G	L	L	D	P	E	S	A	H	R	L	A	V	.	.	.	.	.	R	F	T	S	L	G	L	L	P	F	.	.	.	.	Q	D	S	D	M	L	E	V	R	V	L	G	H	K	F	R	N	P	V	G	I	A	A	.	.	.	.	.	.	.	G	F	D	K	H
Template Known Secondary structure								T									S											.	.	.	.	.					T	T					.	.	.	.				G	G	G					T	T				S	S	S					T	.	.	.	.	.	.	.	T	T	T	T	T
Template Predicted Secondary structure																												.	.	.	.	.											.	.	.	.																								.	.	.	.	.	.	.
Template SS confidence
		35	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60						.	.	.	.	.	.	.	.	.	70					.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.								.	.	.	.	.
		90	.	.	.	.	.	.	.	.	.	100	.	.	.	.		.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.																			.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150
Predicted Secondary structure																	.																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																	.																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	Q	A	A	K	A	A	D	A	H	G	I	P	F	T	.	L	S	T	V	S	V	C	P	I	E	E	V	A	P	A	I	K	R	P	M	W	F	Q	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	V	L	R	D	R	G	F	M	R	N	A	L	E	R	A	K	A	A	G	C	S
Query Conservation																	.																									.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																	.									.	.	.	.													.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																										.	.	.	.
Template Sequence		G	E	A	V	D	G	L	Y	K	M	G	F	G	F	V	E	I	G	S	V	T	P	K	P	.	.	.	.	Q	E	G	N	P	R	P	R	V	F	R	L	P	E	D	Q	A	V	I	N	R	Y	G	F	N	S	H	G	L	S	V	V	E	H	R	L	R	A	R	Q	Q	K	Q	A	K	L	T	E	D	G	L	P
Template Known Secondary structure		S	S								T	T		S									S	S		.	.	.	.	B			S		S							G	G	G	T										B												T	T										T	T
Template Predicted Secondary structure																										.	.	.	.
Template SS confidence
		102	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.					.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.
		151	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230
Predicted Secondary structure
Query SS confidence
Query Sequence		T	L	V	F	T	V	D	M	P	T	P	G	A	R	Y	R	D	A	H	S	G	M	S	G	P	N	A	A	M	R	R	Y	L	Q	A	V	T	H	P	Q	W	A	W	D	V	G	L	N	G	R	P	H	D	L	G	N	I	S	A	Y	L	G	K	P	T	G	L	E	D	Y	I	G	W	L	G	N	N	F	D	P
Query Conservation
Alig confidence																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	G	V	N	L	G	K	N	K	T	S	V	D	A	A	E	D	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	A	E	G	V	R	V	L	G	P	L	A	D	Y	L	V	V	N	V	S	S	P	N	T	A	G	L	R	S	L	Q	G	K	A	E	L	R	R	L	L	T	K
Template Known Secondary structure										T	T		S							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.								G	G	G		S									T	T	S	T	T	S	G	G	G	G	S
Template Predicted Secondary structure																				.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		178	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.																						.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.
		231	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.							.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.																		.	.
Predicted Secondary structure																														.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																														.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		S	I	S	W	K	D	L	E	W	I	R	D	F	W	D	G	P	M	V	I	K	G	I	L	D	P	E	D	.	.	.	.	.	.	A	R	D	A	V	R	F	G	A	D	G	I	V	V	S	N	H	G	G	R	Q	L	D	G	V	L	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	A
Query Conservation																														.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence			.	.																										.	.	.	.	.	.																												.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation			.	.
Template Sequence		V	.	.	L	Q	E	R	D	G	L	R	R	V	H	R	P	A	V	L	V	K	I	A	P	D	L	T	S	Q	D	K	E	D	I	A	S	V	V	K	E	L	G	I	D	G	L	I	V	T	N	T	T	V	S	R	P	A	G	L	Q	G	A	L	R	S	E	T	G	G	L	S	G	K	P	L	R	D	L	S	T
Template Known Secondary structure			.	.						T	S		G	G	G										S																		T										B	S				T	T				T	T	T	T	S	S	S
Template Predicted Secondary structure			.	.
Template SS confidence
		237			.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
		288	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	A	L	P	A	I	A	D	A	V	K	G	D	I	A	I	L	A	D	S	G	I	R	N	G	L	D	V	V	R	M	I	A	L	G	A	D	T	V	L	L	G	R	A	F	L	Y	A	L	A	T	A	G	Q	A	G	V	A	N	L	L	N	L	I	E	K	E	M	K	V	A	M	T	L	T	G	A	K	S	I
Query Conservation
Alig confidence																																																	.	.	.	.	.	.	.				.
Template Conservation																																																	.	.	.	.	.	.	.				.
Template Sequence		Q	T	I	R	E	M	Y	A	L	T	Q	G	R	V	P	I	I	G	V	G	G	V	S	S	G	Q	D	A	L	E	K	I	R	A	G	A	S	L	V	Q	L	Y	T	A	L	T	F	.	.	.	.	.	.	.	W	G	P	.	P	V	V	G	K	V	K	R	E	L	E	A	L	L	K	E	Q	G	F	G	G	V
Template Known Secondary structure											T	T	T		S						S	S			S											T		S					S						.	.	.	.	.	.	.			T	.																	T	T		S	S
Template Predicted Secondary structure																																																	.	.	.	.	.	.	.				.
Template SS confidence
		315	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.								.	.	.		.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.
		368	.	370
Predicted Secondary structure
Query SS confidence
Query Sequence		S	E	I
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T	D	A
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		387	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions