|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 50 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | W | Y | P | W | L | R | P | D | F | E | K | L | V | A | S | Y | Q | A | G | R | G | H | H | A | L | L | I | Q | A | L | P | G | M | G | D | D | A | L | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Y | A | L | S | R | Y | L | L | C | Q |
Query Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|   |
|   |   |
|   |
|
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
|
|   |   |
|
|
|   |
|
|   |   |   |
|   |
| . | . | . | . | . |
|
|
|   |
|   |
|
|
|
|
|
|
|   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | P | S | K | I | Q | E | N | A | L | P | L | M | L | A | E | P | P | Q | N | . |
. |
. |
. |
. |
L | I | A | Q | S | Q | S | G | T | G | K | T | A | A | F | V | L | A | M | L | S | Q | V | E | P | A | N | K | Y | P | Q | C | L | C | L | S | P | T | Y | E | L | A | L | Q | T | G | K | V | I | E | Q | M | G | K | F |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |  |  |  | S | S | S |
|
|
| . | . | . | . | . |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| T | T | S |
| S |
|
|  |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
114 | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . |
  |
  |   |
52 | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | |
. | . | . | . | . | . | 130 |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Query Sequence |   |
Q | P | Q | G | H | K | S | C | G | H | C | R | G | C | Q | L | M | Q | A | G | T | H | P | D | Y | Y | T | L | A | P | E | K | G | K | N | T | L | G | V | D | A | V | R | E | V | T | E | K | L | N | E | H | A | R | L | G | G | A | K | V | V | W | V | T | D | A | A | L | L | T | D | A | . |
A | A | N | A | L | L | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|
|   |   |   |   |   | . |
|   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   | . | . | . | . | . | . | . | . | . |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
Y | P | E | L | K | L | A | Y | A | V | R | G | N | K | L | E | R | G | Q | K | I | S | E | Q | I | V | I | G | T | P | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
T | V | L | D | W | C | S | K | L | K | F | I | D | P | K | K | I | K | V | F | V | L | D | E | A | D | V | M | I | A | T | Q | G | H | Q | D | Q | S | I | R |
Template Known Secondary structure |   |
| S | S |
|
|  |  |  |  | S | T | T |
|
|
|
| S | S |
|
|
|
|
| S |  |  |  |  |
|  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | S |
|
|
|
| G | G | G |
|
|  |  |  |  |
|
|  |  |  |  | T | T | S | T | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|  |  | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
189 | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . |
  |
  |   |
131 | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
|
|
|
. | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . |
|
|  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | L | E | E | P | P | A | E | T | W | F | F | L | A | T | . |
. |
. |
. |
R | E | P | E | R | L | L | A | T | L | R | S | R | C | R | L | H | Y | L | A |
Query Conservation |   |
  |
|
|
|
|   |   |   |   |   |   |
|
|   |
| . | . | . | . |   |   |   |   |   |
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |   |   |   |
|   |
|   |   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
Template Sequence |   |
I | Q | R | M | L | P | R | N | C | Q | M | L | L | F | S | A | T | F | E | D | S | V | W | K | F | A | Q | K | V | V | P | D | P | N | V | I | K | L | K |
Template Known Secondary structure |   |
 |  |  |  | S |
| T | T | S |  |  |  |  |  |  | S |
|
|
|  |  |  |  |  |  |  |  |  |  | S | S | S |
|  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |