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Job DescriptionP77561
Confidence100.00%DateThu Jan 5 12:30:35 GMT 2012
Rank1Aligned Residues663
% Identity23%Templatec1h0hA_
PDB info PDB header:dehydrogenaseChain: A: PDB Molecule:formate dehydrogenase (large subunit); PDBTitle: tungsten containing formate dehydrogenase from2 desulfovibrio gigas
Resolution1.8 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   4950.........60....... ..70.........80.........90.........100.........110.........120.......
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Query Sequence  CPGCAWPDPKHSASFDICE. NGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHELEAAGRLTQPLKYDAVSDCYKPLSW
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Template Sequence  CCYCSVGC. . . . GLIVHTDKKTNRAINVEGDPDHP. . . . INEGSLCAKGASTWQLAENERRPANPLYRAPGSDQWEEKSW
Template Known Secondary structure 
SSBTT

....
TTT


TT
T....TTTT


TS
TTS
SS

TT
SS


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   17..20.... .....30.........40....... ..50.........60.........70.........80........
 
   128.130.........140.. .......150.........160.........170.........180.........190..
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Query Sequence  QQAFDEIGARLQSYS. . . . . . . . . . . . . . . DPNQVEFYTSGRTSNEAAFLYQLFAREYGSNNFPDCSNMCHEPTSVGLAA
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Template Sequence  DWMLDTIAERVAKTREATFVTKNAKGQVVNRCDGIASVGSAAMDNEECWIYQAWLRSLGLFYIEHQAR. IHSATVAALAE
Template Known Secondary structure 
TTS

S

TTS
TTB


GGG.

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   8990.........100.........110.........120.........130.........140.........150...... ...160.......
 
   193......200.........210.........220.........230.........240.........250.........260.........270..
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Query Sequence  SIGVGKGTVLLEDFEKCDLVICIGHNPGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLA
Query Conservation    
         
   

 

  
 

    
     
  
  










 
        
          

  
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Template Sequence  SYGRGAMTNHWIDLKNSDVILMMGSNPAENHPISFKWVMRAKDKGATLIHVDPRYT. . . . . . . . . . . . . . . . . . RTSTKC
Template Known Secondary structure  S

S
SS
TGGGGG
SS

STTTT

SS

..................TTGGG
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   169170.........180.........190.........200.........210.........220.... .....230
 
   273......280.........290.........300.........310.........320.
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Query Sequence  SAYYNVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  DLYAPLRSGSDIAFLNGMTKYILEKE. . . . . . . . . . LYFKDYVVNYTNASFIVGEGFAFEEGLFAGYNKETRKYDKSKWG
Template Known Secondary structure  S


TT
TT..........
S
BGGGBBB
TT

TTTTTTTT
GGGG
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   231........240.........250...... ...260.........270.........280.........290.........300
 
   322.......330.........340.........350........ .360.........370......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . FDELRRDVLNSEWKDIERISGLSQTQIAELADAYAAA. . . . ERTIICYGMGITQHEHGT
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Template Sequence  FERDENGNPKRDETLKHPRCVFQIMKKHYERYDLDKISAICGTPKELILKVYDAYCATGKPDKAGTIMYAMGWTQHTVGV
Template Known Secondary structure  B
B
TTS
B
B
TTS
STTBTT




GGGSTT





SS
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   301........310.........320.........330.........340.........350.........360.........370.........380
 
   377..380.........390.........400.........410.........420.....
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Query Sequence  QNVQQLVNLLLMKGNIGKPGAGICPLRGHSNVQGDRTVGITEKPSAEFL. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  QNIRAMSINQLLLGNIGVAGGGVNALRGEANVQGSTDHGLLMHIYPGYLGTARASIPTYEEYTKKFTPVSKDPQSANWWS
Template Known Secondary structure  TT
SSSTT
S

SBTTTT
BTTTTT

BTT

S





TT


GGG
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   381........390.........400.........410.........420.........430.........440.........450.........460
 
   426...430.........440.........450.........460.........470.........480.......
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Query Sequence  . . . . . . . . . . . . . . . . . . ARLGERYGFTPPHAPGHAAIASMQAICTGQARALICMGGNFALAMPDREASAVPLTQLDLAV
Query Conservation  ..................       
   
   
            
 

 
   
 

  
 

     


 



 
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Template Conservation                                                  

       

    
      


 


 

Template Sequence  NFPKYSASYIKSMWPDADLNEAYGYLPKGEDGKDYSWLTLFDDMFQGKIKGFFAWGQNPACSGANSNKTREALTKLDWMV
Template Known Secondary structure  G
TTS
S

B
TT


STT


S

SBSTT
S
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   461........470.........480.........490.........500.........510.........520.........530.........540
 
   488.490.........500 .........510.........520.........530.........540.........550.......
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Query Sequence  HVATKLNRSHLLT. . . . . . . . . . ARHSYILPVLGRSEIDMQKNGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAG
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Template Sequence  NVNIFDNETGSFWRGPDMDPKKIKTEVFFLPCAVAIEKEG. . . . . . . . SISNSGRWMQWRYVGPEPR. KNAIPDGDLIVE
Template Known Secondary structure  SS

TTTTGGGSTT

GGG


B

GGG

........
TT


SS


.TT
B
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   541........550.........560.........570.........580 .........590......... 600.........610.
 
   558.560.........570.........580.........590.........600.........610....
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Query Sequence  IAQAALPQSVVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERR. . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  LAKRVQKLLAKTPGKLAAPVTKLKTDYWVNDHGHFDPHKIAKLINGFALKDFKVGDVEYKAGQQIATFGHLQADGSTTSG
Template Known Secondary structure  S
TT

S
GGGGB
TTS
B

BBSS
TT
TT
B
S
GGG

TTS
B

S
Template Predicted Secondary structure 
















































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   612.......620.........630.........640.........650.........660.........670.........680.........690.
 
  
Predicted Secondary structure  ................................................................................
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
Template Conservation                                         
                                        
Template Sequence  CWIYTGSYTEKGNMAARRDKTQTDMQAKIGLYPGWTWAWPVNRRIIYNRASVDLNGKPYAPEKAVVEWNAAEKKWVGDVP
Template Known Secondary structure  SGGGTTSTTGGG
B




T

TTBSTTTT
SSTTGGGGB
TTS
BS
GGG
STTTTS

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   692.......700.........710.........720.........730.........740.........750.........760.........770.
 
   615....620....... ..630.........640...
Predicted Secondary structure  .................








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Query Sequence  . . . . . . . . . . . . . . . . . WMTPSGKANFITS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KGLLEDPSSAFNSKLV
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Template Conservation                        
              
    
                                 

  
Template Sequence  DGPWPPQADKEKGKRAFIMKPEGYAYLYGPGREDGPLPEYYEPMECPVIEHPFSKTLHNPTALHFATEEKAVCDPRYPFI
Template Known Secondary structure  SS
S

TT
TTT


S
TTSSSS
B
SS
TTSTT
SS






SSS



SS
S

S
TT

SS

SS




TTS
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   772.......780.........790.........800.........810.........820.........830.........840.........850.
 
   644.....650.........660.........670.........680.........690.........700.........710.........720...
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Query Sequence  MATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAKICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSL
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Template Sequence  CSTYRVTEHWQTGLMTRNTPWLLEAEPQMFCEMSEELATLRGIKNGDKVILESVRGKLWAKAIITKRIKPFAIQGQQVHM
Template Known Secondary structure 

TT

TTSTSS
S

T

TT
TT
TT


TT
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   852.......860.........870.........880.........890.........900.........910.........920.........930.
 
   724.....730.........740.........750........
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Query Sequence  . . . . . . . . . . . . VTYFPESNHMLTLDNHDPLSGIPGYKSIPVELEPS
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Template Conservation 
  
   
       
   
 

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Template Sequence  VGIPWHYGWSFPKNGGDAANILTP. SVGNPNTGIPETKAFMVNVTKA
Template Known Secondary structure  S


TTSSTTS


GGGS

.BSSS
SSBSB

S

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   932.......940.........950..... ....960.........970.......
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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