|   |
1 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | |
. | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
| . |
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
M | K | V | L | V | I | G | N | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | E | H | A | L | A | W | K | A | A | Q | S | P | L | V | E | T | V | F | V | A | P | G | N | A | . |
G | T | A | L | E | P | A | L | Q | N | V | A | I | G | V | T | D | I | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|
|
|
|
|
|   |
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |
|   |
|
|   |
|
|   |
|   |
|   |   |
|
|
|   |
|
|   |   |
|   |   |
|
|   |   | . | . |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | R | V | G | I | V | F | G | G | K | S | A | E | H | E | V | S | L | Q | S | A | K | N | I | V | D | A | I | D | K | . |
. |
T | R | F | D | V | V | L | L | G | I | D | K | A | G | Q | W | H | V | N | D | A | E | N | Y | L | Q | N | A | D | D | P | A | H | I | A | L | R | P | S | A | I | S | L | A | Q | V | P | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| T | . | . | T | T |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |
| S | S | S | S | B | S | S | T | T |
| T | T | T |
|
| B |
|
|
| S |
| B |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . |
  |
  |   |
|
|
|
|
|
|
|
|
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
L | L | D | F | A | Q | N | E | K | I | D | L | T | I | V | G | P | E | A | P | L | V | K | . |
. |
G | V | V | D | T | F | R | A | A | G | L | K | I | F | G | P | T | A | G | A | A | Q | L | E | G | S | K | A | F | T | K | D | F | L | A | R | H | K | I | P | T | A | E | Y | Q | N | F |
Query Conservation |   |
. | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   | . | . |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |
Template Sequence |   |
K | H | Q | H | Q | L | I | N | A | Q | N | G | Q | P | L | P | T | V | D | V | I | F | P | I | V | H | G | T | L | G | E | D | G | S | L | Q | G | M | L | R | V | A | N | L | P | F | V | G | S | D | V | L | S | S | A | A | C | M | D | K | D | V | A | K | R | L | L | R | D | A | G | L | N | I | A | P | F | I | T | L |
Template Known Secondary structure |   |
| S | S | S |
|  |  |  | T | T | T |
|
| B |
|
|
|
| S |  |  |  |  |
|
|
| S | T | T | T | T | S | S |  |  |  |  |  |  |  |  | T | T |
|
| B | S | S |
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| B |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
82 | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . |
  |
  |   |
126 | . | |
|
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . |
Predicted Secondary structure |   |
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | E | . |
. |
. |
. |
V | E | P | A | L | A | Y | L | R | E | K | G | A | P | I | V | I | K | A | D | G | L | A | A | G | K | G | V | I | V | A | M | T | L | E | E | A | E | A | A | V | H | D | M | L | A | G | N | A | F | G | D | A | G | H | R | I | V | I | E | E | F | L | D | G | E | E | A | S | F | I | V | M | V |
Query Conservation |   |
  |
| . | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
|   |
|   |
|
|   |   |   |   |
Alig confidence |   |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |
|   |
|   |   |
|   |
|   |   |
Template Sequence |   |
T | R | T | N | R | H | A | F | S | F | A | E | V | E | S | R | L | G | L | P | L | F | V | K | P | A | N | Q | G | S | S | V | G | V | S | K | V | A | N | E | A | Q | Y | Q | Q | A | V | A | L | A | F | E | F | . |
. |
. |
. |
. |
. |
D | H | K | V | V | V | E | Q | G | I | K | G | R | E | I | E | C | A | V | L | G |
Template Known Secondary structure |   |
 | T | T | T | G | G | G |
|
|  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  | T | T |
|
| T | T | T | T |
|  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
| S |  |  |  |  |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
162 | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
  |
  |   |
202 | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | G | E | H | V | L | P | M | A | T | S | Q | D | H | K | R | V | G | D | K | D | T | G | P | N | T | G | G | M | G | A | Y | S | P | A | P | V | V | T | D | D | V | H | Q | R | T | M | E | R | I | I | W | P | T | V | K | G | M | A | A | E | G | N | T | Y | T | G | F | L | Y | A | G | L | M | I | D | K | Q | G | N |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
| . | . |   |   |
|   |   |   |
|
|   |   |   |
|   |
|
|   |
Template Sequence |   |
N | D | N | P | Q | A | S | T | C | G | E | I | V | L | N | S | E | F | Y | D | T | K | Y | I | D | D | N | G | A | Q | V | V | V | P | A | Q | . |
. |
. |
. |
. |
I | P | S | E | V | N | D | K | I | R | A | I | A | I | Q | A | Y | Q | T | L | G | . |
. |
C | A | G | M | A | R | V | D | V | F | L | T | A | D | N | E |
Template Known Secondary structure |   |
S | S | S |
|  |  |  |  |  |  |  |  |  |
|
| T | T |
|
| T | T | T | T | S | G | G | G | G |
|  |  |  | S | S |
| S | . | . | . | . | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . |
|
|  |  |  |  |  |  |  |  |  |
| T | T |
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . |
  |
  |   |
282 | . | . | . | . | . | . | . | 290 | . | . | |
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | K | V | I | E | F | N | C | R | F | G | . |
. |
. |
D | P | E | T | Q | P | I | M | L | R | M | K | S | D | L | V | E | L | C | L | A | A | C |
Query Conservation |   |
  |   |
|
|
|
|
|   |
|   |
| . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
V | V | I | N | E | I | N | T | L | P | G | F | T | N | I | S | M | Y | P | K | L | W | Q | A | S | G | L | G | Y | T | D | L | I | S | R | L | I |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S | S |
|
|
| S | T | T |
|  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
311 | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
  |