Job Description P15640 Confidence 100.00% Date Wed Jan 25 15:20:39 GMT 2012 Rank 20 Aligned Residues 404 % Identity 16% Template c1w96B_ PDB info PDB header:ligase Chain: B: PDB Molecule:acetyl-coenzyme a carboxylase; PDBTitle: crystal structure of biotin carboxylase domain of acetyl-2 coenzyme a carboxylase from saccharomyces cerevisiae in3 complex with soraphen a Resolution 1.8 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.													.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.								50	.	.	.	.	.	.	.	.	.	60	.	.
Predicted Secondary structure																										.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.
Query SS confidence																										.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.
Query Sequence		K	V	L	V	I	G	N	G	G	R	E	H	A	L	A	W	K	A	A	Q	S	P	L	V	.	.	.	.	.	.	.	.	.	.	.	.	E	T	V	F	V	A	P	G	N	A	G	T	A	L	E	P	A	L	Q	N	V	A	I	G	.	.	.	.	.	.	.	V	T	D	I	P	A	L	L	D	F	A	Q	N
Query Conservation																										.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.
Alig confidence																										.	.	.	.	.	.	.	.	.	.	.	.																									.	.	.	.	.	.	.
Template Conservation
Template Sequence		K	I	L	I	A	N	N	G	I	A	A	V	K	E	I	R	S	V	R	K	W	A	Y	E	T	F	G	D	D	R	T	V	Q	F	V	A	M	A	T	P	E	D	L	E	A	N	A	E	Y	I	R	M	A	D	Q	Y	I	E	V	P	G	G	T	N	N	N	N	Y	A	N	V	D	L	I	V	D	I	A	E	R
Template Known Secondary structure																												S		T	T	S	S													T	T							S	S								S	S	G	G	G	T	T	T
Template Predicted Secondary structure
Template SS confidence
		61	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140
		63	.	.	.	.	.	.	70	.	.	.		.	.	.	.	.	.	80	.	.	.	.	.	.	.			.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.
Predicted Secondary structure													.															.	.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence													.															.	.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	K	I	D	L	T	I	V	G	P	E	.	A	P	L	V	K	G	V	V	D	T	F	R	A	A	.	.	G	L	K	I	F	G	P	T	A	G	A	A	Q	L	E	G	S	K	A	F	T	K	D	F	L	A	R	H	K	I	P	T	A	E	Y	Q	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation													.															.	.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence													.															.	.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		A	D	V	D	A	V	W	A	G	W	G	H	A	S	E	N	P	L	L	P	E	K	L	S	Q	S	K	R	K	V	I	F	I	G	P	P	G	N	A	M	R	S	L	G	D	K	I	S	S	T	I	V	A	Q	S	A	K	V	P	C	I	P	W	S	G	T	G	V	D	T	V	H	V	D	E	K	T	G	L	V
Template Known Secondary structure		T	T		S						S	S	T	T	T	T		T									S	T	T					S	S									S		S											T	T			B			B	T	T	T	T								T	T	T
Template Predicted Secondary structure
Template SS confidence
		141	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220
												124	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.
Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.																																																																						.
Query SS confidence		.	.	.	.	.	.	.	.	.	.																																																																						.
Query Sequence		.	.	.	.	.	.	.	.	.	.	N	F	T	E	V	E	P	A	L	A	Y	L	R	E	K	G	A	P	I	V	I	K	A	D	G	L	A	A	G	K	G	V	I	V	A	M	T	L	E	E	A	E	A	A	V	H	D	M	L	A	G	N	A	F	G	D	A	G	H	R	I	V	I	E	E	F	L	D	G	.
Query Conservation		.	.	.	.	.	.	.	.	.	.																																																																						.
Alig confidence		.	.	.	.	.	.	.	.	.	.																																																					.	.	.	.														.
Template Conservation																																																																.	.	.	.
Template Sequence		S	V	D	D	D	I	Y	Q	K	G	C	C	T	S	P	E	D	G	L	Q	K	A	K	R	I	G	F	P	V	M	I	K	A	S	E	G	G	G	G	K	G	I	R	Q	V	E	R	E	E	D	F	I	A	L	Y	H	Q	A	A	N	E	I	.	.	.	.	P	G	S	P	I	F	I	M	K	L	A	G	R	A
Template Known Secondary structure									G	G	G	S		S	S													S	S						T	T			S	S	T	T					S	S	G	G	G												S	.	.	.	.	T	T											S
Template Predicted Secondary structure																																																																.	.	.	.
Template SS confidence
		221	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.					.	.	.	.	.	.	.	290	.	.	.	.	.	.
		193	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		E	E	A	S	F	I	V	M	V	D	G	E	H	V	L	P	M	A	T	S	Q	D	H	K	R	V	G	D	K	D	T	G	P	N	T	G	G	M	G	A	Y	S	P	A	P	V	V	T	D	D	V	H	Q	R	T	M	E	R	I	I	W	P	T	V	K	G	M	A	A	E	G	N	T	Y	T	G	F	L	Y	A
Query Conservation
Alig confidence																										.	.	.	.	.	.																						.	.	.	.																	.	.
Template Conservation																										.	.	.	.	.	.																						.	.	.	.																	.	.
Template Sequence		R	H	L	E	V	Q	L	L	A	D	Q	Y	G	T	N	I	S	L	F	G	R	D	C	S	.	.	.	.	.	.	V	Q	R	R	H	Q	K	I	I	E	E	A	P	V	T	I	A	K	A	E	T	.	.	.	.	F	H	E	M	E	K	A	A	V	R	L	G	K	L	V	G	.	.	Y	V	S	A	G	T	V
Template Known Secondary structure												T	T	S												.	.	.	.	.	.				T	T								S			S	S					.	.	.	.																T	.	.
Template Predicted Secondary structure																										.	.	.	.	.	.																						.	.	.	.																	.	.
Template SS confidence
		297	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320							.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.					.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.			.	.	360	.	.	.	.
		273	.	.	.	.		.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.					.	.	.	.	.	.	.	340	.	.	.	.	.	.	.
Predicted Secondary structure							.																																																								.	.	.	.
Query SS confidence							.																																																								.	.	.	.
Query Sequence		G	L	M	I	D	.	K	Q	G	N	P	K	V	I	E	F	N	C	R	F	G	D	P	E	T	Q	P	I	M	L	R	M	K	S	D	L	V	E	L	C	L	A	A	C	E	S	K	L	D	E	K	T	S	E	W	D	E	R	A	S	L	.	.	.	.	G	V	V	M	A	A	G	G	Y	P	G	D	Y	R	T
Query Conservation							.																																																								.	.	.	.
Alig confidence							.																				.																																				.	.	.	.
Template Conservation																											.
Template Sequence		E	Y	L	Y	S	H	D	D	G	K	F	Y	F	L	E	L	N	P	R	L	Q	V	E	H	P	.	T	T	E	M	V	S	G	V	N	L	P	A	A	Q	L	Q	I	A	M	G	I	P	M	H	R	I	S	D	I	R	T	L	Y	G	M	N	P	H	S	A	S	E	I	D	F	E	F	K	T	Q	D	A	T	K
Template Known Secondary structure							T	T	T	T										S			T	T	T		.																			T	T			G	G	G								T	T			T	T							T	T			S
Template Predicted Secondary structure																											.
Template SS confidence
		365	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.		390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.
		348																	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.		.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410
Predicted Secondary structure			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																			.
Query SS confidence			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																			.
Query Sequence		G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	D	V	I	H	G	L	P	L	E	E	V	A	G	G	K	V	F	H	A	G	T	K	L	A	D	D	E	Q	V	V	T	N	G	G	.	R	V	L	C	V	T	A	L	G	H	T	V	A	E	A	Q	K	R	A	Y	A	L	M	T	D	I	H	W
Query Conservation			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																			.
Alig confidence			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																				.	.	.													.
Template Conservation																																						.	.	.
Template Sequence		K	Q	R	R	P	I	P	K	G	H	C	T	A	C	R	I	T	G	T	L	H	E	L	N	F	R	S	S	S	N	V	W	G	Y	F	S	.	.	.	V	G	N	N	G	N	I	H	S	F	S	D	S	Q	F	G	H	I	F	A	F	G	E	N	R	Q	A	S	R	K	H	M	V	V	A	L	K	E	L	S	I
Template Known Secondary structure										S																	S	S		S	S							.	.	.			T	T		S	S		S	S		S											S	S
Template Predicted Secondary structure																																						.	.	.
Template SS confidence
		444	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.				480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520
		411	.		.						.	.	.	.	.	.	420	.	.	.	.	.
Predicted Secondary structure				.		.	.	.	.	.
Query SS confidence				.		.	.	.	.	.
Query Sequence		D	D	.	C	.	.	.	.	.	F	C	R	K	D	I	G	W	R	A	I	E
Query Conservation				.		.	.	.	.	.
Alig confidence				.		.	.	.	.	.
Template Conservation
Template Sequence		R	G	D	F	R	T	T	V	E	Y	L	I	K	L	L	E	T	E	D	F	E
Template Known Secondary structure		T	T	S	S												T	S
Template Predicted Secondary structure
Template SS confidence
		533	.	.	.	.	.	.	540	.	.	.	.	.	.	.	.	.	550	.	.	.