|   |
2 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | |
. | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
K | V | L | V | I | G | N | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | E | H | A | L | A | W | K | A | A | Q | S | P | . |
L | V | E | T | V | F | V | A | P | G | N | A | G | T | A | L | E | P | A | L | Q | N | V | A | I | G | V | T | D | I | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|
|
|
|
|   |
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |   |   |   | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|
|   |
|
|   |
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | V | A | L | I | F | G | G | N | S | S | E | H | D | V | S | K | R | S | A | Q | N | F | Y | N | A | I | E | A | T | G | K | Y | E | I | I | V | F | A | I | A | Q | N | G | F | F | L | D | T | E | S | S | K | K | I | L | A | L | E | D | E | Q | P | I | V | D | A | F | M | K | T | V | D | A | S | D | P | L | A | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |
| S | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |
|  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  | T | T |
|
| T | T |
| T | T |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
405 | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . |
  |
  |   |
56 | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
L | L | D | F | A | Q | N | E | K | I | D | L | T | I | V | G | P | E | A | P | L | V | K | . |
. |
G | V | V | D | T | F | R | A | A | G | L | K | I | F | G | P | T | A | G | A | A | Q | L | E | G | S | K | A | F | T | K | D | F | L | A | R | H | K | I | P | T | A | E | Y | Q | N | F | T | E | V | E | . |
. |
. |
. |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   | . | . |   |   |
|   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |   |   |   |   |   |
|   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | H | A | L | K | S | A | G | D | F | D | I | F | F | P | V | V | H | G | N | L | G | E | D | G | T | L | Q | G | L | F | K | L | L | D | K | P | Y | V | G | A | P | L | R | G | H | A | V | S | F | D | K | A | L | T | K | E | L | L | T | V | N | G | I | R | N | T | K | Y | I | V | V | D | P | E | S | A | N | N | W |
Template Known Secondary structure |   |
 |  | T | T | S | T | T |
|
|
| S |  |  |  |  |
|
| T | T | T | T | T | S | S | S |  |  |  |  |  |  |  |  | T | T |
|
| B | S | S |
|
|  |  |  |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|  |  |  |  |
| T | T | G | G | G | G |
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
485 | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . |
  |
  |   |
130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | |
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
| . |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | A | L | A | Y | L | R | E | K | G | A | P | I | V | I | K | A | D | G | L | A | A | G | K | G | V | I | V | A | M | T | L | E | E | A | E | A | A | V | H | D | M | L | A | G | N | A | F | G | D | A | G | H | R | I | V | I | E | E | F | L | D | G | . |
E | E | A | S | F | I | V | M | V | D | G | E | H | V | L | P |
Query Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |
| . |   |
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |   |
|
|
|   |
|   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | W | D | K | I | V | A | E | L | G | N | I | V | F | V | K | A | A | N | Q | G | S | S | V | G | I | S | R | V | T | N | A | E | E | Y | T | E | A | L | S | D | S | F | Q | Y | . |
. |
. |
. |
. |
. |
D | Y | K | V | L | I | E | E | A | V | N | G | A | R | E | L | E | V | G | V | I | G | N | D | Q | P | L | V | S |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  | T |
| S |
|  |  |  |  |  | S | S |
|
| S | S | T | T |
|  |  |  |
| S |  |  |  |  |  |  |  |  |  |  |  | T | T | T | . | . | . | . | . | . |
| S |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  | S | S | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
565 | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . |
  |
  |   |
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | A | T | S | Q | D | H | K | R | V | G | D | K | D | T | G | P | N | T | G | G | M | G | A | Y | S | P | A | P | V | V | T | D | D | V | H | Q | R | T | M | E | R | I | I | W | P | T | V | K | G | M | A | A | E | G | N | T | Y | T | G | F | L | Y | A | G | L | M | I | D | K | Q | G | N | P | K | V | I | E | F | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
| . | . |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
Template Sequence |   |
E | I | G | A | H | T | V | H | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | I | P | A | Q | L | S | P | E | V | T | K | E | V | K | Q | M | A | L | D | A | Y | K | V | L | N | . |
. |
L | R | G | E | A | R | M | D | F | L | L | D | E | N | N | V | P | Y | L | G | E | P | N |
Template Known Secondary structure |   |
 |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . |
|
|  |  |  |  |  |  |  |  |  |
| T | T |
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
639 | 640 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | |
|
. | . | . | . | . | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . |
  |
  |   |
289 | 290 | . | . | |
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
| . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
C | R | F | G | . |
. |
. |
D | P | E | T | Q | P | I | M | L | R | M | K | S | D | L | V | E | L | C | L | A | A | C |
Query Conservation |   |
  |
|   |
| . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |
|
Template Sequence |   |
T | L | P | G | F | T | N | M | S | L | F | K | R | L | W | D | Y | S | D | I | N | N | A | K | L | V | D | M | L | I |
Template Known Secondary structure |   |
S | S |
|
|
| S | T | T | S | G | G | G | T | T | G | G | G | G | T |
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
719 | 720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . | . | . | . | 740 | . | . | . | . | . | . | . | . |
  |