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Job DescriptionP37747
Confidence100.00%DateThu Jan 5 11:57:23 GMT 2012
Rank16Aligned Residues354
% Identity18%Templatec2v1dA_
PDB info PDB header:oxidoreductase/repressorChain: A: PDB Molecule:lysine-specific histone demethylase 1; PDBTitle: structural basis of lsd1-corest selectivity in histone h32 recognition
Resolution3.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20.........30.........40.........50.........60.... .....70.........80
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Query Sequence  YDYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFHTNDKY. IWDYVNDLVEFNRFTN
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Template Sequence  GKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVAD. LGAMVVTGLGGNPMAVVSKQVNMELAKIK
Template Known Secondary structure  S

STT

SSSSS
TT

TT.SS



SBT
TT



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   279280.........290.........300.........310.........320........ .330.........340.........350.......
 
   81........90.........100.........110.........120.........130.........140.
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Query Sequence  SPLAIYKDKLFNLPFNMNTFHQMWGVKDPQEAQNIINAQKKKYGDKVPENLEEQAISLVGE. . . . . . . . . . . . . . . . . . .
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Template Sequence  QKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKT
Template Known Secondary structure 




B
TTSSB

TS


TT
B
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   358.360.........370.........380.........390.........400.........410.........420.........430.......
 
  
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  QEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPS
Template Known Secondary structure  S
SS

TTS


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   438.440.........450.........460.........470.........480.........490.........500.........510.......
 
   142.......150.........160.........170.........180.........190.........200.........210...
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Query Sequence  . . . . . . . . DLYQALIKGYTEKQWGRSAKELPAFIIKRIPVRFTFDNNYFSDRYQGIPVGGYTKLIEKMLEGVDVKLGIDF
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Template Sequence  DVYLSSRDRQILDWHFANLEFANATPLSTLS. . . . . . . LKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAV
Template Known Secondary structure  S
SS
TTS
TTTBB.......TTTTTTTGGG

BS

TT
TTTT


S
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   518.520.........530.........540........ .550.........560.........570.........580.........590
 
   214... ..220.........230...... ...240.........250.........260
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Query Sequence  LKDK. . . . . . . . . . . . . . . . . DSLASKAHRIIYTGPIDQY. . . . . . . . . . . . . . . . FDYRFGALEYRSLKFETERHEFPN
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Template Conservation    
                         
 

 
 
   
        
 
 

     

     
    
 
 
    
Template Sequence  RQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVF
Template Known Secondary structure  TTSSSTT
S



SS
SSS


S



SS

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   591........600.........610.........620.........630.........640.........650.........660.........670
 
   261........270.........280.........290....... ..300..
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Query Sequence  FQGNAVINFTDANVPYTRIIEHKHFDYVETKHTVVTK. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EYPLE
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Template Conservation          
                   
  

     
  
      
  
        
                

 
Template Sequence  WDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSR
Template Known Secondary structure  S
TT




SSSTTTTTT

SSSS
TTS

TTTS


S

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   671........680.........690.........700.........710.........720.........730.........740.........750
 
   303...... 310.........320.........330... ......340........ .350.........360.....
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Query Sequence  WKVGDEP. . YYPVNDNKNMELFKKYRELASRED. . . . . . . . . . . . . KVIFGGRLAEYKYYD. MHQVISAALYQVKNIMS
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Template Sequence  WRADPWARGSYSYVAAGSSGNDYDLMA. . QPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIAD
Template Known Secondary structure  TTT
TTTSSS

BTT

..S
B



SSTTS






SGGG
TTSTTS
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   751........760.........770....... ..780.........790.........800.........810.........820.......
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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