Job Description P24169 Confidence 99.91% Date Thu Jan 5 11:40:44 GMT 2012 Rank 28 Aligned Residues 306 % Identity 17% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		173	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190		.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.				.	.	.	.	.	.	220	.	.	.	.	.	.				.	.	.	230	.	.	.	.	.	.	.	.	.					240	.
Predicted Secondary structure																				.																								.	.	.														.	.	.														.	.	.	.
Query SS confidence																				.																								.	.	.														.	.	.														.	.	.	.
Query Sequence		E	G	A	P	C	I	A	Q	Q	H	A	A	K	V	F	N	A	D	.	K	T	Y	F	V	L	N	G	T	S	S	S	N	K	V	V	L	N	A	L	L	T	P	.	.	.	G	D	L	V	L	F	D	R	N	N	H	K	S	.	.	.	N	H	H	G	A	L	L	Q	A	G	A	T	P	.	.	.	.	V	Y
Query Conservation																				.																								.	.	.														.	.	.														.	.	.	.
Alig confidence																				.																								.	.	.														.	.	.														.	.	.	.
Template Conservation
Template Sequence		I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T	V	N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M
Template Known Secondary structure		G	G	T	T					G	G	G					T			G	G	G					S																		S	S	S							T	T																T	T
Template Predicted Secondary structure
Template SS confidence
		110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.
		242	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.		.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320
Predicted Secondary structure																																																							.
Query SS confidence																																																							.
Query Sequence		L	E	T	A	R	N	P	Y	G	F	I	G	G	I	D	A	H	C	F	E	E	S	Y	L	R	E	L	I	A	E	V	A	P	Q	R	A	K	E	A	R	P	F	R	L	A	V	I	Q	L	G	T	Y	D	.	G	T	I	Y	N	A	R	Q	V	V	D	K	I	G	H	L	C	D	Y	I	L	F	D	S	A	W
Query Conservation																																																							.
Alig confidence								.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.										.
Template Conservation								.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.
Template Sequence		I	K	P	R	E	G	.	.	.	.	.	.	.	.	.	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	.	.	.	.	.	.	.	I	L	F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H
Template Known Secondary structure						T	T	.	.	.	.	.	.	.	.	.		S	S														G	G	G				.	.	.	.	.	.	.					S	B		T	T	T		B	B													T	T								T	T
Template Predicted Secondary structure								.	.	.	.	.	.	.	.	.																							.	.	.	.	.	.	.
Template SS confidence
		190	.	.	.	.	.										.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.								.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.
		321	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.		.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380																.	.	.	.
Predicted Secondary structure																																								.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																								.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		V	G	Y	E	Q	F	I	P	M	M	A	D	C	S	P	L	L	L	D	L	N	E	N	D	P	G	I	L	V	T	Q	S	V	H	K	Q	Q	A	.	G	F	S	Q	T	S	Q	I	H	K	K	D	S	H	I	K	G	Q	Q	R	Y	V	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	P	H	K	R
Query Conservation																																								.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence					.	.	.	.	.	.	.	.													.	.	.	.												.																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation					.	.	.	.	.	.	.	.													.	.	.	.
Template Sequence		A	V	G	.	.	.	.	.	.	.	.	N	V	E	L	Y	L	H	D	W	G	V	D	.	.	.	.	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q
Template Known Secondary structure		T	T	T	.	.	.	.	.	.	.	.	T	S								T			.	.	.	.						S	S	S	T	T				T	T									G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S
Template Predicted Secondary structure					.	.	.	.	.	.	.	.													.	.	.	.
Template SS confidence
		254	.	.									.	.	.	260	.	.	.	.	.	.	.	.					.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.
		385	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		M	N	N	A	F	M	M	H	A	S	T	S	P	F	Y	P	L	F	A	A	L	N	I	N	A	K	M	H	E	G	V	S	G	R	N	M	W	M	D	C	V	V	N	G	I	N	A	R	K	L	I	L	D	N	C	Q	H	I	R	P	F	V	P	E	L	V	D	G	K	P	W	Q	S	Y	E	T	A	Q	I	A
Query Conservation
Alig confidence																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		B		S	S	G	G	G	G			S																																																			S		S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																																		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		322	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.
		465	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.	.	.	.	490	.	.	.	.	.					.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540
Predicted Secondary structure																																	.	.	.	.
Query SS confidence																																	.	.	.	.
Query Sequence		V	D	L	R	F	F	Q	F	V	P	G	E	H	W	H	S	F	E	G	Y	A	E	N	Q	Y	F	V	D	P	C	K	.	.	.	.	L	L	L	T	T	P	G	I	D	A	R	N	G	E	Y	E	A	F	G	V	P	A	T	I	L	A	N	F	L	R	E	N	G	V	V	P	E	K	C	D	L	N	S	I	L
Query Conservation																																	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.					.	.	.	.								.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	.	.	.	.	.	.	.	.	.	.	.	.	.	P	N	K	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	R	N	P	N	G	I	R
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	G	G	G	B		S									.	.	.	.	.	.	.	.	.	.	.	.	.	T	T									T	T	T							T	T	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																													395	.	.	.	.	400	.	.	.	.	.	.	.	.	.														410	.	.	.	.	.	.	.	.	.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.
		541	.	.		.	.	.	.	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.
Predicted Secondary structure					.
Query SS confidence					.
Query Sequence		F	L	L	.	T	P	A	E	D	M	A	K	L	Q	Q	L	V	A	L	L	V	R	F
Query Conservation					.
Alig confidence					.
Template Conservation
Template Sequence		V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T	S	I
Template Known Secondary structure			B			T	T	T
Template Predicted Secondary structure
Template SS confidence
		435	.	.	.	.	440	.	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions