|   |
22 | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | A | A | T | E | S | P | L | W | L | G | V | D | L | G | T | C | D | V | V | S | M | V | V | D | R | D | G | Q | P | V | A | V | C | L | D | W | A | D | V | V | R | D | G | I | V | W | D | F | F | G | A | V | T | I | V | R | R | H | L | D | T | L | E | Q | Q | F | G | R | R | F | S | H | A | A | T | S | F | P |
Query Conservation |   |
  |   |   |   |   |   |   |
|
|   |
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   | . | . | . | . | . | . |   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
Template Sequence |   |
X | X | Y | T | N | D | N | R | I | V | X | T | L | D | A | G | G | T | N | F | V | F | S | A | I | Q | G | G | K | E | I | A | D | P | V | V | L | P | A | C | A | D | C | . |
. |
. |
. |
. |
. |
L | D | K | C | L | G | N | L | V | E | G | F | K | A | I | Q | A | G | L | P | E | A | P | V | A | I | S | F | A | F | P |
Template Known Secondary structure |   |
| T | T | T | T |
|
|
|  |  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |  | T | T |  |  |
| S |
|
|  |  |  |  |
|
| T | T |
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|
|
|  |  |  |  |  |
|
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
102 | . | . | . | . | . | . | |
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | G | T | D | P | R | I | . |
S | I | N | V | L | E | S | A | G | L | E | V | S | H | V | L | D | E | P | T | A | V | A | D | L | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | L | D | N | A | G | V | V | D | I | G |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|
|   |
|   |   |
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|
|
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |   |
|   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
|   |
|
|
|
|
|
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|   |
|
Template Sequence |   |
G | P | A | D | Y | Q | A | G | I | I | G | D | L | P | N | F | P | S | F | R | G | G | V | A | L | G | P | F | L | E | D | I | F | G | I | P | V | F | I | N | N | D | G | S | L | F | A | Y | G | E | A | L | T | G | V | L | P | E | I | N | R | R | L | R | E | A | G | S | T | K | R | Y | K | N | L | L | G | V | T | L |
Template Known Secondary structure |   |
S | S |  |  | T | T | T | T |  |  |
|
|
| T | T |
| G | G | G | T | T |
| B |
|  |  |  |  |  |  |  |  |  |
| S |
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | G | T | T | G | I | A | I | V | K | K | G | K | V | T | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | A | D | E | A | T | G | G | H | H | I | S | L | T | L | A | G | N | R | R | I | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | E | A | E | Q | Y | K | R | G | H | G | E | E |
Query Conservation |   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|   |
|
|
|
|   |
|   |
|   |   |
|   |   |
|   |
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |
|
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|
|   |   |   |
Template Sequence |   |
G | T | G | F | G | A | G | V | V | I | D | G | E | L | L | R | G | D | N | A | A | G | G | Y | V | W | C | L | R | N | K | K | Y | P | E | Y | I | V | E | E | S | V | S | I | R | A | V | X | R | V | Y | A | E | R | S | G | D | A | G | A | R | T | P | K | E | I | F | E | I | A | E | G | I | R | P | G | N | R | E | A |
Template Known Secondary structure |   |
S | S | S |  |  |  |  |  |  |  | T | T |  |  |
|
|
| T | T | S |
| T | T |
|
| T | T | S | B |
| S | S |
| T | T | S | B | G | G | G | T | S | S |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
| S |
|
|
|  |  |  |  |  |  |  |  |  | T | S | S |
| S |
|  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . |
  |
  |   |
198 | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | W | P | A | V | K | P | V | Y | E | K | M | A | D | I | V | A | R | H | I | E | G | Q | G | I | T | D | L | W | L | A | G | G | S | C | . |
. |
. |
. |
. |
M | Q | P | G | V | A | E | L | F | R | K | Q | F | P | A | L | Q | V | H | L | P | Q | H | S | L | F | M | T | P | L | A | I | A | S | S | G | R | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|
|   |
| . | . | . | . | . |   |
|
|   |
|   |   |   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |
|
|
| . |   |   |
|
|
|
|
|
|
|
|   |
|   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
|
|   |   |
|
|
|   |   |   |   |   |
Template Sequence |   |
A | I | A | A | F | E | E | L | G | E | X | A | G | D | A | L | A | S | A | I | T | L | I | D | . |
G | L | I | V | I | G | G | G | L | S | G | A | S | K | Y | I | L | P | V | L | L | K | E | X | N | A | Q | T | G | X | X | Q | K | E | V | Y | D | L | D | E | E | K | S | F | A | G | F | A | R | G | E | A | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | S |  |  |  |  |  | S | G | G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  | T | T |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
235 | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | |
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . |
  |