|   |
1 | . | . | . | . | . | . | . | . | 10 | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 40 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | D | I | I | F | Y | H | P | T | F | D | . |
. |
. |
. |
. |
. |
. |
T | Q | W | W | I | E | A | L | R | K | A | I | P | Q | A | R | V | R | A | W | K | S | G | D | N | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | D | Y | A | L | V | W | H | P | P | V |
Query Conservation |   |
|   |
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |   |
|   |   |   |   |
|   |
|
|
|
|
|
|   |   |
|   |   |
|   |   |   | . | . |
|   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |
Template Sequence |   |
M | R | V | G | I | P | T | E | T | K | N | N | E | F | R | V | A | I | T | P | A | G | V | A | E | L | T | R | R | . |
. |
G | H | E | V | L | I | Q | A | G | A | G | E | G | S | A | I | T | D | A | D | F | K | A | A | G | A | Q | L | V | G | T | A | D | Q | V | W | A | D | A | D | L | L | L | K | V | K | E | P | I |
Template Known Secondary structure |   |
|  |  |  |  |
|
|
|
| S | T | T |
|
|
|
| S |
|
|  |  |  |  |  |  |  |  | T | T | . | . | T |
|  |  |  |  | B | T | T | T | T | G | G | G | T |
|
| S |  |  |  |  | T | T |
|
|
|
| B | S | S |  |  |  |  |  | S | S |
| S |  |  |  |
| S | S |
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
E | M | L | A | G | R | D | L | K | A | V | F | A | L | G | A | G | V | D | S | I | L | S | K | L | Q | A | H | P | E | M | L | N | P | S | V | P | L | F | R | L | E | D | T | G | M | G | E | Q | M | Q | E | Y | A | V | S | Q | V | L | H | W | F | R | R | F | D | D | Y | R | I | Q | Q | N | S | S | H | W |
Query Conservation |   |
. | . | . |   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |
| . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
A | A | E | Y | G | R | L | R | H | G | Q | I | L | F | T | F | L | H | L | A | A | S | R | A | C | T | D | A | L | L | D | S | G | T | T | S | I | A | Y | E | . |
. |
. |
. |
. |
. |
T | V | Q | T | A | D | G | A | L | P | L | L | A | P | M | S | E | V | A | G | R | L | A | A | Q | V | G | A | Y | H | L | M | R | T |
Template Known Secondary structure |   |
G | G | G | G | G | G |
|
| S | S | S |  |  |  |  |
|
|
| G | G | G |
|  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  | G | G | . | . | . | . | . | . | G |
|
|
| T | T | S |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
127 | . | . | 130 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 190 | . |
Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | P | L | P | E | . |
. |
. |
. |
. |
. |
Y | H | R | E | D | F | T | I | G | I | L | G | A | G | V | L | G | S | K | V | A | Q | S | L | Q | T | W | R | F | P | L | R | C | W | S | R | T | R | K | S | W | P | G | V | Q | S | F | A | G | R | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
E | L | S | A | F | L | S | Q | C |
Query Conservation |   |
  |   |   |   |   | . | . | . | . | . | . |   |   |
|   |
|   |
|
|
|
|
|
|   |
|   |
|
|   |   |
|
|   |   |
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |
|   |   |
|
|   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|
|   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
Template Sequence |   |
Q | G | G | R | G | V | L | M | G | G | V | P | G | V | E | P | A | D | V | V | V | I | G | A | G | T | A | G | Y | N | A | A | R | I | A | N | G | M | G | A | T | V | T | V | L | D | I | N | I | D | K | L | R | Q | L | D | A | E | F | C | G | R | I | H | T | R | Y | S | S | A | Y | E | L | E | G | A | V | K | R | A |
Template Known Secondary structure |   |
G | T | S |
|
|
|
| T | T |
| B | T | T | B |
|
|
|  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  | T | T | T |
| S |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
  |
  |   |
192 | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | V | L | I | N | L | L | P | N | T | P | E | T | V | G | I | I | N | Q | Q | L | L | E | K | L | P | D | G | A | Y | L | L | N | L | A | R | G | V | H | V | V | E | D | D | L | L | A | A | L | D | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | K | V | K | G | A | M | L | D | V | F | N | R | E | P | L | P | P | E | S |
Query Conservation |   |
|
|
|   |   |   |   |
|
|
|   |   |
|   |   |
|
|   |   |   |   |
|   |   |
|
|   |
|
|   |
|
|
|
|   |
|
|   |
|
|
|   |   |
|
|   |   |
|
|   |   | . | . | . | . | . | . | . | . | . |
|   |
|   |
|
|   |
|
|
|   |   |   |
|
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
D | L | V | I | G | A | V | L | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | A | H | M | K | P | G | A | V | L | V | D | I | T | L | F | Y | C | M | P | A | S | V | P | K | T | S | T | Y | A | L | T | N | A | T | M | P | Y | V | L | E | L | A | D | H | G | W | R | A | A | C | R | S | N | P | A | L | A | K |
Template Known Secondary structure |   |
S |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| T | T |
|  |  |  |  |
|
|
|  |  |
|
| G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 |
  |
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | L | W | Q | H | P | R | V | T | I | T | P | H | V | A | A | I | T |
Query Conservation |   |
|
|   |   |   |   |
|
|   |   |
|
|
|   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |
|   |
|
|   |   |   |
|
|   |   |   |
Template Sequence |   |
G | L | S | T | H | E | G | A | L | L | S | E | R | V | A | T | D | L |
Template Known Secondary structure |   |
T |  |  |  |  | T | T |  |  |
|
|  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|  |  |
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
342 | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . |
  |