|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | |
|
|
|
|
|
|
. | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |
|  |  |  |  |  |
|
|
|  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
M | D | I | I | F | Y | H | P | T | F | D | T | . |
. |
. |
. |
. |
. |
. |
Q | W | W | I | E | A | L | R | K | A | I | P | Q | A | R | V | R | A | W | K | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | D | N | D | S | A | D | Y | A | L | V | W | H | P | P | V | . |
Query Conservation |   |
|   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |
|
|
|   |
|
|   |   |   |   |
|
|
|
|   |
|
|
|   |   |
|   |   |
|   |   |   | . | . |
|   |   |
|   |
|
|   |   |
|
|   |   |   |   |
|   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
|   |   |
Template Sequence |   |
M | E | I | G | V | P | K | E | I | K | N | Q | E | F | R | V | G | L | S | P | S | S | V | R | T | L | V | E | A | . |
. |
G | H | T | V | F | I | E | T | Q | A | G | I | G | A | G | F | A | D | Q | D | Y | V | Q | A | G | A | Q | V | V | P | S | A | K | D | A | W | S | R | E | M | V | V | K | V | K | E | P | L | P |
Template Known Secondary structure |   |
|  |  |  |  |
|
|
|
| S | T | T |
|
|
|
| S |
|
|  |  |  |  |  |  |  |  | T | T | . | . | T |
|  |  |  |  |  | T | T | T | T | G | G | G | T |
|
|  |  |  |  |  |  |  | T |
|  |  |  | S | S |  |  |  |  |  | T | S | S |  |  |  |
| S | S |
|
|
| G |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
E | M | L | A | G | R | D | L | K | A | V | F | A | L | G | A | G | V | D | S | I | L | S | K | L | Q | A | H | P | E | M | L | N | P | S | V | P | L | F | R | L | E | D | T | G | M | G | E | Q | M | Q | E | Y | A | V | S | Q | V | L | H | W | F | R | R | F | D | D | Y | R | I | Q | Q | N | S | S | H | W | Q |
Query Conservation |   |
. | . |   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |   |   |   |
| . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
A | E | Y | D | L | M | Q | K | D | Q | L | L | F | T | Y | L | H | L | A | A | A | R | E | L | T | E | Q | L | M | R | V | G | L | T | A | I | A | Y | E | . |
. |
. |
. |
. |
. |
T | V | E | L | P | N | R | S | L | P | L | L | T | P | M | S | I | I | A | G | R | L | S | V | Q | F | G | A | R | F | L | E | R | Q | Q |
Template Known Secondary structure |   |
G | G | G | G | G |
|
| T | T |
|  |  |  |  |
|
|
| G | G | G |
|  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  | G | G | . | . | . | . | . | . | G |
|
|
| T | T | S |
|
| T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | G | G | G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . |
  |
  |   |
128 | . | 130 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . |
Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | L | P | E | Y | . |
. |
. |
. |
. |
. |
H | R | E | D | F | T | I | G | I | L | G | A | G | V | L | G | S | K | V | A | Q | S | L | Q | T | W | R | F | P | L | R | C | W | S | R | T | R | K | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
W | P | G | V | Q | S | F | A | G | R | E | E | L | S | A | F | L | S | Q | C | R |
Query Conservation |   |
  |   |   |   |   | . | . | . | . | . | . |   |
|   |
|   |
|
|
|
|
|
|   |
|   |
|
|   |   |
|
|   |   |
|   |
|
|
|   |   |
|   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|
|   |
|   |
|
|   |   |
|
|   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
G | G | R | G | V | L | L | G | G | V | P | G | V | K | P | G | K | V | V | I | L | G | G | G | V | V | G | T | E | A | A | K | M | A | V | G | L | G | A | Q | V | Q | I | F | D | I | N | V | E | R | L | S | Y | L | E | T | L | F | G | S | R | V | E | L | L | Y | S | N | S | A | E | I | E | T | A | V | A | E | A | D |
Template Known Secondary structure |   |
T | S |
|
|
|
| T | T |
| B | T | T | B |
|
|
|  |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G | S |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  | T |
| S |
Template Predicted Secondary structure |   |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . |
  |
  |   |
193 | . | . | . | . | . | |
. | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | |
|
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
| . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
| . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | I | N | L | L | . |
P | N | T | P | E | T | V | G | I | I | N | Q | Q | L | L | E | K | L | P | D | G | A | Y | L | L | N | L | A | . |
. |
R | G | V | H | V | V | E | D | D | L | L | A | A | L | D | S | G | K | V | K | G | A | M | L | D | V | F | N | R | E | P | L | P | P | E | S | P | L | W | Q | H | P | R |
Query Conservation |   |
|
|   |   |   |   | . |
|
|
|   |   |
|   |   |
|
|   |   |   |   |
|   |   |
|
|   |
|
|   |
|
|
|
|   | . | . |
|
|   |
|
|
|   |   |
|
|   |   |
|
|   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |
|
|
|   |   |   |   |
|
|   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |   |   |
|   |   |
|
|   |
|   |
|
|
|
|
|
|   |
|   |
|
|   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
Template Sequence |   |
L | L | I | G | A | V | L | V | P | G | R | R | A | P | I | L | V | P | A | S | L | V | E | Q | M | R | T | G | S | V | I | V | D | V | A | V | D | Q | G | G | C | V | E | T | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | P | T | S | H | T | Q | P | T | Y | E | V | F | G |
Template Known Secondary structure |   |
 |  |  |  |
|
|
|
| T | T | S | S |
|
|
|
| B |
|  |  |  |  | T | T | S |
| T | T |
|  |  |  |  | T | T |
| T | T |
|
| S | B | T | T |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
| S | S | S |
|  |  |  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
233 | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . |
  |
  |   |
270 | . | . | |
|
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  | . | . |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | I | . |
. |
T | P | H | V | A | A | I | T | R | P | A | E | A | V | E | Y | I | S | R | T | I | A | Q | L | E |
Query Conservation |   |
|   |   | . | . |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |
|
|   |   |   | . |
|   |   |
|
|   |   |   |
|   |   |
|   |   |   |
|
Template Sequence |   |
V | V | H | Y | G | V | P | N | M | P | G | A | V | . |
P | W | T | A | T | Q | A | L | N | N | S | T | L | P | Y | V |
Template Known Secondary structure |   |
 |  |  |  |
|
| S |
| G | G | G | G |
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
292 | . | . | . | . | . | . | . | 300 | . | . | . | . | |
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |