Return to main results Retrieve Phyre Job Id

Job DescriptionP28903
Confidence99.84%DateThu Jan 5 11:45:16 GMT 2012
Rank4Aligned Residues530
% Identity14%Templatec3hnfA_
PDB info PDB header:oxidoreductaseChain: A: PDB Molecule:ribonucleoside-diphosphate reductase large subunit; PDBTitle: crystal structure of human ribonucleotide reductase 1 bound to the2 effectors ttp and datp
Resolution3.16 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   18.20.........30.........40.........50.........60.........70... ......80........
Predicted Secondary structure 












.........
Query SS confidence 























































. . . . .














. . . .
Query Sequence  ERIKEAILRAAKAAEVDDADYCATVAAVVSEQMQGRNQVDINEIQTAVENQLMSGP. . . . . YKQLARAYIEYRHDR. . . .
Query Conservation   

  

 

       
      
   
         



 


 

  
 
 
.....   


 

 

  
....
Alig confidence 















.


















..

















.....














....
Template Conservation   

   
     

  .   
   
           .. 

 

       
       
     



    
 
    
Template Sequence  DKITSRIQKLCYGLNM. DFVDPAQITMKVIQGLYSG. . VTTVELDTLAAETAATLTTKHPDYAILAARIAVSNLHKETKK
Template Known Secondary structure  GGGGTTS
T.TT

TTS

SS..

GGGT
TTTS
S
Template Predicted Secondary structure 




.







..








Template SS confidence 















































































   16...20.........30. ........40.........50 .........60.........70.........80.........90..
 
   8990.........100.........110.........120.........
Predicted Secondary structure  .......................................














Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .








































Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . DIEREKRGRLNQEIRGLVEQTNASLLNENANKDSKVIPTQR
Query Conservation  .......................................   
         
             



          
Alig confidence  .......................................




























.










Template Conservation                                        
   
   

    
     
  




  .    
 

   
Template Sequence  VFSDVMEDLYNYINPHNGKHSPMVAKSTLDIVLANKDRLNSAIIYDRDFSYNYFGFKTLERSYLLKIN. GKVAERPQHML
Template Known Secondary structure 

B
TTT

B

SS
TTTT

GGGGGSS
TS
BSS.SSB


Template Predicted Secondary structure 
















.


Template SS confidence 















































































   93......100.........110.........120.........130.........140.........150.........160 .........170.
 
   130.........140.........150.........160.........170.........180.........190... ......200........
Predicted Secondary structure 





























.






Query SS confidence 































































.














Query Sequence  DLLAGIVAKHYARQHLLPRDVVQAHERGDIHYHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNA. EIEPPKSISTATAVT
Query Conservation     
  
 
 
 
   

 

  

  







          
    
  

  

     . 
 




 

    
Alig confidence 







.........












.





















.









.



..








Template Conservation   


  

.........         

  .

      


 
 



   
.





     


 .. 
       
Template Sequence  MRVSVGIH. . . . . . . . . KEDIDAAIETYNL. LSERWFTHASPTLFNAGTNRPQ. LSSCFLLSMKDDSIE. . GIYDTLKQC
Template Known Secondary structure  .........TT
.TTS
TTSSS

.






SS..
Template Predicted Secondary structure  .........


.













.








..
Template SS confidence 















































































   172....... 180.........190.. .......200.........210.... .....220......... 230........
 
   209210.........220.........230.... .....240.........250.........260.........270.........280.....
Predicted Secondary structure 





...





Query SS confidence 

























. . .


















































Query Sequence  AQIIAQVASHIYGGTTINRIDEVLAP. . . FVTASYNKHRKTAEEWNIPDAEGYANSRTIKECYDAFQSLEYEVNTLHTAN
Query Conservation    

   
   




   

  


...

     
  
             
       
 
  
   
 

 
    
Alig confidence 



.....








..





...




























......















Template Conservation 
 
 .....
 




  .. 
 

  

 
    
 


 
 
 
  
     
 
 ......

   

  




  
Template Sequence  ALIS. . . . . KSAGGIGVA. . VSCIRATGSYIAGTNGNSNGLVPMLRVYNNTARYVDQP. . . . . . GAFAIYLEPWHLDIFE
Template Known Secondary structure  .....T


..
TTS

TT
TTTT






......


TTBTT
Template Predicted Secondary structure  .....



..























......






Template SS confidence 















































































   239240.. .......250. ........260.........270.........280......... 290.........300.....
 
   286...290.........300.........310.........320........ .330.........340
Predicted Secondary structure 























.........................





Query SS confidence 










































. . . . . . . . . . . . . . . . . . . . . . . . .











Query Sequence  GQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFP. . . . . . . . . . . . . . . . . . . . . . . . . KLVFAIRDGLNH
Query Conservation   
 


 
        
   
  


     
         

.........................     
      
Alig confidence 





......





















...





.........................








...
Template Conservation 

  
 ......     

 
 
 

 

  
  ...
 

 
     
    
  
   
   
      
 
 

...
Template Sequence  FLDLKK. . . . . . RDLFFALWIPDLFMKRVETNQD. . . WSLMCPNECPGLDEVWGEEFEKLYASYEKQGRVRKVVKAQ. . .
Template Known Secondary structure  TTS

......


TT
...B
TTTSTTTTS

TT


S...
Template Predicted Secondary structure  ......









...






...
Template SS confidence 















































































   311..... ...320.........330........ .340.........350.........360.........370........
 
   341........350.........360.........370.........380.........390.........400.. .......410......
Predicted Secondary structure 











































....

Query SS confidence 





























































. . . .













Query Sequence  KKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWENENGEQIHDG. . . . RNNLGVISLNLPRI
Query Conservation     


 

        

 
 
 
 
              



  
       
     
.... 

 









Alig confidence  .......



































......












....













Template Conservation  .......

   
      

 
 
 
 
  
        
 
......  



 

 
     
   


 



  
Template Sequence  . . . . . . . QLWYAIIESQTETGTPYMLYKDSCNRKSNQQNLGTI. . . . . . KCSNLCTEIVEYTSKDEVAVCNLASLALNMY
Template Known Secondary structure  .......S
ST
TTGGG


......



TTS






SS


B

GGGS
Template Predicted Secondary structure  .......












......












Template SS confidence 















































































   388.390.........400.........410.........420... ......430.........440.........450....
 
   417..420.........430.........440.........450.........460.........470.........480.........490......
Predicted Secondary structure 





















Query SS confidence 















































































Query Sequence  ALEAKGDEATFWKLLDERLVLARKALMTRIARLEGVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHE
Query Conservation 
  
  
   
   

  



   
  
            
 
   
                     
 


 


 
Alig confidence 
.






..




















....................
















.









Template Conservation 
.     

..   
   
  


 

 


 ....................   
           
 .




 



Template Sequence  V. TSEHTYD. . FKKLAEVTKVVVRNLNKIIDI. . . . . . . . . . . . . . . . . . . . NYYPVPEACLSNKRHRP. IGIGVQGLAD
Template Known Secondary structure  B.
TTS
B
......................


SS

.

Template Predicted Secondary structure 
.






......................





.



Template SS confidence 















































































   455 ....460.. .......470.........480... ......490.........500 .........510
 
   497..500.........510.........520.........530.. .......540 .........550......
Predicted Secondary structure 







....


................



Query SS confidence 



































. . . .







. . . . . . . . . . . . . . . .















Query Sequence  TINALFGGEHVYDNEQLRAKGIAIVERLRQAVDQWK. . . . EETGYGFS. . . . . . . . . . . . . . . . LYSTPSENLCDRFCRL
Query Conservation      
 
            
   

  
        ....

 
    ................

 




   



 
Alig confidence 




...



























....



.


................















Template Conservation   
  
...

 
 
 

  
   
 
 
   
  

 




 
. 
  
  
    
    
           
  
 
Template Sequence  AFILM. . . RYPFESAEAQLLNKQIFETIYYGALEASCDLAKEQG. PYETYEGSPVSKGILQYDMWNVTPTDLWDWKVLKE
Template Known Secondary structure  ...T

TTS
.

TT
TTSTTTTT

TT



TTS
Template Predicted Secondary structure 
...






.




















Template SS confidence 















































































   511.... ....520.........530.........540.........550. ........560.........570.........580......
 
   557..560... ..... .570.......
Predicted Secondary structure 


................




..







.........................................
Query SS confidence 






. . . . . . . . . . . . . . . .




. .








. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  DTAEFGV. . . . . . . . . . . . . . . . VPGVT. . DKGYYTNSF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 
   

 ................
 
  ..
  




 .........................................
Alig confidence 






................




..








.........................................
Template Conservation   
   
 


 
 






 
 
 
 
 



  
  
 
    
    

  
   
   
         
    


Template Sequence  KIAKYGIRNSLLIAPMPTASTAQILGNNESIEPYTSNIYTRRVLSGEFQIVNPHLLKDLTERGLWHEEMKNQIIACNGSI
Template Known Secondary structure 

S
S

B




TT


TT


S
S

B
SSSB


TT


TTT

Template Predicted Secondary structure 































Template SS confidence 















































































   587..590.........600.........610.........620.........630.........640.........650.........660......
 
   578.580.........590.........600.........610.........620.........630 ..
Predicted Secondary structure  ............


















.

Query SS confidence  . . . . . . . . . . . .




















































.

Query Sequence  . . . . . . . . . . . . HLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDVWDYSYQ. HV
Query Conservation  ............
 

       


  
        

 
 
  
 
      

  
      . 
Alig confidence  ............




































..













.

Template Conservation 
    

      
 

 

     
 
 
  
  





 

     ..
   
   
  


 

Template Sequence  QSIPEIPDDLKQLYKTVWEISQKTVLKMAAERGAFIDQSQSLNIHIAEP. . NYGKLTSMHFYGWKQGL
Template Known Secondary structure  TT
TTS
T

GGGS
TTS
SS





SS
..
T
Template Predicted Secondary structure 


















..



Template SS confidence 



































































   667..670.........680.........690.........700.........710..... ....720.........730..
 
Download:Text version FASTA pairwise alignment 3D Model in PDB format

View in Jmol

Send structure to FirstGlance for more viewing options


Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions