|   |
75 | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | Q | L | A | R | A | Y | I | E | Y | R | H | D | R | D | I | E | R | E | K | R | G | R | L | N | Q | E | I | R | G | L | V | E | Q | T | N | A | S | L | L | N | E | N | A | N | K | D | S | K | V | I | P | T | Q | R | D | L | L | A | G | I | V | A | K | H | Y | A | R | Q | H | L | L | P | R | D | V | V | Q | A | H |
Query Conservation |   |
  |   |
|
|
|   |
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |
|   |   |   |
|
|   |
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |
|   |   | . |   |   |   |   |
|   |
|
|   |   |   |   |
|
|
|   |   |   |
| . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
Template Sequence |   |
D | D | V | Y | N | I | V | M | E | N | K | D | K | L | N | S | A | I | V | Y | D | R | D | F | Q | Y | S | Y | F | G | F | K | T | L | E | R | S | Y | L | L | R | I | N | . |
G | Q | V | A | E | R | P | Q | H | L | I | M | R | V | A | L | G | I | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | D | I | E | A | A | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |
|
| G | G | G | G | G | G | S |
|  |  |  |  |  |  |  |  |  |  | T | S |
|  |  | T | . | T |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | T | T |
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
118 | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
180 | . | . | . | . | . | . | . |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | |
. | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | R | G | D | I | H | Y | H | D | L | D | Y | S | P | F | F | P | M | F | N | C | M | L | I | D | L | K | G | M | L | T | Q | G | F | K | M | G | N | A | . |
E | I | E | P | P | K | S | I | S | T | A | T | A | V | T | A | Q | I | I | A | Q | V | A | S | H | I | Y | G | G | T | T | I | N | R | I | D | E | V | L | A |
Query Conservation |   |
  |   |
|
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|
|   |   |   |   |   | . |   |
|   |
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |
|
|
|
|
|   |   |   |
|
|   |   |
|
|
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   | . |
|
|   |   |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |   |   |
| . |
|
|
|
|
|
|   |   |
|   |   |
|
|   |   | . | . |   |
|   |   |   |   |   |   |   |
|   |
|   | . | . | . | . | . |
|   |
|
|
|
|
|   |   | . | . |   |
|   |
|
|
Template Sequence |   |
E | T | Y | N | L | . |
M | S | L | K | Y | F | T | H | A | S | P | T | L | F | N | A | G | T | P | K | P | Q | . |
M | S | S | C | F | L | V | A | M | K | E | D | S | I | E | . |
. |
G | I | Y | D | T | L | K | E | C | A | L | I | S | . |
. |
. |
. |
. |
K | T | A | G | G | I | G | L | H | . |
. |
I | H | N | I | R |
Template Known Secondary structure |   |
 |  |  |  |  | . |  |  | T | T | S |  |  |  |
|  |  |  |  |  |  | T | T | S | S | S |
|
| . |
|
|
|  |  |  |  |  |
|
|
| S | S |  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | T | S | S |
|  |  |  |  |  | . | . |
| T | T | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  | . |  |  |
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |
|
|
|  |  |  |  | . | . |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
188 | . | 190 | . | . | |
. | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | |
|
230 | . | . | . | . | . | . | . | . | . | 240 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 250 | . | |
|
. | . | . | . | . |
  |
  |   |
234 | |
|
|
. | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | |
. | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | |
|
|
. | . | . | 300 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
| . | . | . |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | . |
. |
. |
F | V | T | A | S | Y | N | K | H | R | K | T | A | E | E | W | N | I | P | D | A | E | G | Y | A | N | S | R | T | I | . |
K | E | C | Y | D | A | F | Q | S | L | E | Y | E | V | N | T | L | H | T | A | N | G | Q | T | P | F | V | T | F | G | F | G | . |
. |
. |
L | G | T | S | W | E | S | R | L | I |
Query Conservation |   |
| . | . | . |
|
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |
|   |
|   |   |
|   |   |   |
|   |
|
|   |
|   |   |   |   |   |
|   |
|
|
|   |
|   |   |   | . | . | . |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|   |   |   |   |
|   |
|
|
|   |
|   |
|   |   |   |   |
|   |   |   |   |   |
|   |
|
|
|   |   |
|   |
|
|   |   |   |   |
| . | . |   |   |   |
|
|
|
|   |   |
|
|   |   |
|   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |
|
|   |
|
Template Sequence |   |
S | T | G | S | Y | I | A | G | T | N | G | T | S | N | G | L | I | P | M | I | R | V | F | N | N | T | A | R | Y | V | D | Q | G | G | N | K | R | P | G | A | F | A | L | Y | L | . |
. |
E | P | W | H | A | D | I | F | D | F | I | D | I | R | K | N | H | G | K | E | E | I | R | A | R | D | L | F | P | A | L | W | I |
Template Known Secondary structure |   |
| T | T |
| B |
| T | T | S | S |
| B |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
| S | S | S |
| S | S |
|
|
|  |  |  |  |  | . | . |
| T | T | B | T | T |  |  |  |  | T | T | T | T |
| S | S | S |
| S | T | T |
|
| T | T |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . |
  |
  |   |
307 | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | E | S | I | L | R | N | R | I | A | G | L | G | K | N | R | K | T | A | V | F | P | K | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | F | A | I | R | D | G | L | N | H | K | K | G | D | P | N | Y | D | I | K | Q | L | A | L | E | C | A | S | K | R |
Query Conservation |   |
  |   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |   |   |   |   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
| . | . |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|   |   |
|   |   |
|   |   | . |
| . | . |   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |
|   |   |   |   |   |   |
|
Template Sequence |   |
P | D | L | F | M | K | R | V | E | E | N | G | T | . |
W | . |
. |
T | L | F | S | P | T | S | A | P | G | L | S | D | C | Y | G | D | E | F | E | A | L | Y | T | R | Y | E | K | E | G | R | G | K | T | I | K | A | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | L | W | Y | S | I | L | E | A | Q | T | E | T |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  | T |
|  | . |  | . | . |  |  | B |
| T | T | T | S | T | T | G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |
|
|
|
| . |  | . | . |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | |
. | |
|
. | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 390 | . | . | . | . | . | . | . | . | . |
  |
  |   |
361 | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | |
|
|
|
. | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | |
|
|
|
. | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | Y | P | D | I | L | N | Y | D | Q | V | V | K | V | T | G | S | F | K | T | P | M | G | C | R | S | F | L | G | V | W | E | N | E | N | G | E | Q | I | H | D | G | . |
. |
. |
. |
R | N | N | L | G | V | I | S | L | N | L | P | R | I | A | . |
. |
. |
. |
L | E | A | K | G | D | E | A | T | F | W | K | L | L | D |
Query Conservation |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
| . | . | . | . |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|   |
|   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |
| . | . | . | . | . | . |   |   |
|
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|
| . | . |   |   |   |
|   |
Template Sequence |   |
G | T | P | F | V | V | Y | K | D | A | C | N | R | K | S | N | Q | K | N | L | G | V | I | . |
. |
. |
. |
. |
. |
K | S | S | N | L | C | C | E | I | V | E | Y | S | A | P | D | E | T | A | V | C | N | L | A | S | V | A | L | P | A | F | I | E | T | S | E | D | G | K | T | S | T | Y | N | . |
. |
F | K | K | L | H |
Template Known Secondary structure |   |
S |
| S |  |  |  |  |  |  |  |  |  |  | T |
| T | T | G | G | G |
|
|
| . | . | . | . | . | . |
|
|
|
| T | T | S |
|
|
|
|
|
| B | T | T | B |
|  |  |  |
|  |  |  |  |  | G | G | G | G |  |  |
| T | T | S | S | S |
|
|  |  |
| . | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | |
|
. | . | . | 470 | . |
  |
  |   |
433 | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | R | L | V | L | A | R | K | A | L | M | T | R | I | A | R | L | E | G | V | K | A | R | V | A | P | I | L | Y | M | E | G | A | C | G | V | R | L | N | A | D | D | D | V | S | E | I | F | K | N | G | R | A | S | I | S | L | G | Y | I | G | I | H | E | T | I | N | A | L | F | G | G | E | H | V | Y | D | N | E | Q |
Query Conservation |   |
  |   |
|
|
|
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |
|
|
|   |
|
|   |
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   | . |
|
|
|
|
|   |
|
|
|
|   |
|   |   |
| . | . | . |
|
|   |
|   |
|   |
|
Template Sequence |   |
E | I | A | K | V | V | T | R | N | L | N | R | V | I | D | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | Y | Y | P | V | E | E | A | R | K | S | N | M | R | H | R | P | . |
I | A | L | G | V | Q | G | L | A | D | T | F | M | L | L | . |
. |
. |
R | L | P | F | D | S | E | E |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| S | S |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |
|  |  |  |  |  |  |  | T | . | . | . | T |
|
| T | T | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|  |  |  |
|
|
|  |  |  |  |  |  |  |
| . | . | . |
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
472 | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | |
. | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | |
|
|
520 | . | . | . | . | . | . | . |
  |
  |   |
513 | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 540 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | A | K | G | I | A | I | V | E | R | L | R | Q | A | V | D | Q | W | K | E | E | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Y | G | F | S | L | Y | S | T | P | S | E |
Query Conservation |   |
  |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|
|   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|   |   |
|
|   |
|
|
|
|
|   |
|   |
|
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |
|   |
|
|
|   |
|   |
|
|
|
|
Template Sequence |   |
A | R | L | L | N | I | Q | I | F | E | T | I | Y | H | A | S | M | E | A | S | C | E | L | A | Q | K | D | G | P | Y | E | T | F | Q | G | S | P | A | S | Q | G | I | L | Q | F | D | M | W | D | Q | K | P | Y | G | M | W | D | W | D | T | L | R | K | D | I | M | K | H | G | V | R | N | S | L | T | M | A | P | M | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| T | T |
| T | T | S | T | G | G | G | T |
|
| G | G | G | G | G | T |
|
|
|
|
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |
|
| S |
| S |
|
| B |
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
528 | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . |
  |
  |   |
548 | . | 550 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 580 | . | . | . |
Predicted Secondary structure |   |
 |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | L | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | R | F | C | R | L | D | T | A | E | F | G | V | V | P | G | V | T | D | K | G | . |
. |
. |
. |
. |
Y | Y | T | N | S | F | H | L | D | V | E | K |
Query Conservation |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|
|
|
|   |
|   |   |   |
|
|   |
|   |
|   |   |
|   |   | . | . | . | . | . |
|
|
|
|
|   |
|   |
|
|   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|
|
|   |
|   |
|   |
|   |
|   |
|
|
|
|   |   |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |
|
|   | . | . | . | . | . | . |
Template Sequence |   |
T | A | S | T | S | Q | I | L | G | Y | N | E | C | F | E | P | V | T | S | N | M | Y | S | F | Q | V | V | N | P | Y | L | L | R | D | L | V | D | L | G | I | W | D | E | G | M | K | Q | Y | L | I | T | Q | N | G | S | I | Q | G | L | P | N | V | P | Q | E | L | K | D | L | Y | K | T | V | W | . |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
| T | T |  |  |  |  |  | T |
|
| S | T | T |
|
|
| S |
| S | S |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | T | T |
|
| S |  |  |  |  |  |  |  |  |  | T | T | T |
|
| S | S |
| T | T |
|
|  |  |  |  |  |  | S |
|
| G | G | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
608 | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | |
|
|
|
|
|
  |
  |   |
584 | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | |
. | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Query Sequence |   |
K | V | N | P | Y | D | K | I | D | F | E | A | P | Y | P | P | L | A | N | G | G | F | I | C | Y | G | E | Y | P | N | I | Q | H | N | L | K | A | L | E | D | V | W | D | Y | S | Y | Q | . |
H | V |
Query Conservation |   |
  |   |   |   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|   |
|   |
|   |   |
|   |
|   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   | . |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
Template Conservation |   |
|
|   |   |   |   |   |
|   |
|   |
|   |   |
|   |   |
|
|
|
|
|
|   |
|
|   |   |   |   |   | . | . |
|   |   |
|
|   |   |   |
|   |   |
|
|
|   |
|
|
Template Sequence |   |
E | I | S | Q | K | T | I | I | N | M | A | A | D | R | S | V | Y | I | D | Q | S | H | S | L | N | L | F | L | R | A | P | . |
. |
T | M | G | K | L | T | S | M | H | F | Y | G | W | K | K | G | L |
Template Known Secondary structure |   |
G | S |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |
| S | S |
|
|
|
|
|  |  |
| S | S |
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
689 | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . | . | . | . | . | . | 710 | . | . | . | . | . | . | . | . | . | |
|
720 | . | . | . | . | . | . | . | . | . | 730 | . | . | . | . | . | . |
  |