|   |
14 | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
Query Sequence |   |
V | A | V | I | E | F | N | Y | G | R | K | L | N | A | L | S | K | V | F | I | D | D | L | M | Q | A | L | S | D | L | N | R | P | E | I | R | C | I | I | L | R | A | P | S | G | S | K | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | S | A | G | H |
Query Conservation |   |
|   |   |
|   |
|
|
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|   |
|
|   |   |
|
|   |
|   |   |
|   |   |
|   |   |
|
|   |
|
|
|   |   |   |   |
|
|   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|
|   |   |   |
Template Sequence |   |
I | I | L | I | S | N | D | I | T | F | R | I | G | S | F | G | P | G | E | D | L | L | Y | L | R | A | S | E | L | A | R | A | E | G | I | P | R | V | Y | L | A | A | N | S | G | A | R | I | G | L | A | E | E | I | K | H | M | F | Q | V | A | W | V | D | P | E | D | P | H | K | G | I | K | Y | L | Y | L | T | P | Q |
Template Known Secondary structure |   |
 |  |  |  |  |  |
| T | T | S | G | G | G |
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |
|
|
|
| B |
|
|
|
|
|  |  |  |  | T | T |
|  |  |  |  | S | S | S | S | S | G | G | G |
|  |  |  |  |  |  |
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . |
  |
  |   |
67 | . | . | 70 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | H | E | L | P | S | G | G | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | P | L | S | Y | D | D | P | L | R | Q | I | T | R | M | I | Q | K | F | P | K | P | I | I | S | M | V | E | G | S | V | W | G | G | A | F | E | M | I | M | S | S |
Query Conservation |   |
|
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|
|   |
|   |
|   |
|   |
|
|
|   |   |
|
|   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |
|
|
|   |   |   |
|   |
|
|
|   |
|   |
|
|
|   |
|
|   |
|   |
|
|
|   |   | . |   |
|
|
|
|
|   |
|   |
|   |   |   |
|
|
|
|
|
|
|   |
|   |
Template Sequence |   |
D | Y | T | R | I | S | S | L | N | S | V | H | C | K | H | V | E | E | D | G | E | S | R | Y | V | I | T | D | I | I | G | K | E | E | G | L | G | V | E | N | L | R | G | S | G | M | I | A | G | E | T | S | Q | D | Y | D | . |
E | I | V | T | I | S | M | V | S | C | R | A | L | G | I | G | A | Y | L | V | R | L | G |
Template Known Secondary structure |   |
 |  |  |  | T | T | T |
|
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
|
| S | S | S | S | S | S | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  | S |
|  |  |  |  |  |
| S |  |  |  | T |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
193 | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
. | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . |
  |
  |   |
119 | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
. | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|  |  |  | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | L | I | I | A | A | S | T | S | T | F | S | M | T | P | V | N | L | G | V | P | Y | N | L | V | G | I | H | N | L | T | R | D | A | G | F | H | I | . |
V | K | E | L | I | F | T | A | S | P | I | T | A | Q | R | A | L | A | V | G | I | L | N | H | V | V | E | V | E | E | L | E | D | F | T | L | Q | M | A | H | H |
Query Conservation |   |
|   |
|
|
|   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   | . |
|   |   |
|   |
|   |
|   |   |   |   |
|   |
|
|   |   |   |
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|   |   |   |
|   |
|   |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|   |
|
|   |   |   |
|
|
|
|
|
|   |
|   |
|
|
|
|
| . | . | . | . |
|   |
|
|   |   |
|
|
|
|
|   |   |
|   |
|
| . | . | . |   |
|
|
|   |   |
|
|   |
Template Sequence |   |
Q | R | V | I | Q | V | E | N | S | H | I | I | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | A | T | A | L | N | K | V | L | G | R | D | V | Y | T | S | N | N | Q | L | G | G | . |
. |
. |
. |
V | Q | I | M | H | H | N | G | V | S | H | V | T | V | P | D | D | . |
. |
. |
F | E | G | V | C | T | I | L | E |
Template Known Secondary structure |   |
|  |  |  |  |  | T | T |
|  |  |  | S | S | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  | T | S |
|
|
| S |
| T |  |  |  |  | S | . | . | . | . |  |  |  |  | T | T | T | T | S |
| S |  |  |  | S | S |  | . | . | . |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |
|
|  |  |
|
|
|  |  |
|
|
|  | . | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  | . | . | . |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
272 | . | . | . | . | . | . | . | 280 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | |
|
|
|
. | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | |
|
|
. | . | . | . | . | 330 | . | . | . |
  |
  |   |
198 | . | 200 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
Query Sequence |   |
I | S | E | K | A | P |
Query Conservation |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|
|
Template Sequence |   |
W | L | S | Y | M | P |
Template Known Secondary structure |   |
 |  | T | T | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
  |   |
334 | . | . | . | . | . |
  |