Phyre Home Retrieve Phyre Job Id
Emaill.a.kelley@imperial.ac.uk
DescriptionP62522
DateThu Jan 5 12:07:34 GMT 2012
Unique Job ID9dec9dbd79aa0d98

Summary 

Top model
Image coloured by rainbow N → C terminus
Model (left) based on template c3mraA_
Top template information
PDB header:membrane protein
Chain: A: PDB Molecule:nicotinic acetylcholine receptor;
PDBTitle: m3 transmembrane segment of alpha-subunit of nicotinic2 acetylcholine receptor from torpedo californica, nmr, 153 structures
Confidence and coverage
Confidence: 25.8% Coverage: 38%
12 residues ( 38% of your sequence) have been modelled with 25.8% confidence by the single highest scoring template.
You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.
Please note: You must be registered and logged in to use Phyrealarm.
3D viewing
Interactive 3D view in Jmol

Sequence analysis 

Secondary structure and disorder prediction 

   1........10.........20.........30..
Sequence  MTALLRVISLVVISVVVIIIPPCGAALGRGKA
Secondary structure 








SS confidence 































Disorder  ??





















????????
Disorder confidence 































 

Confidence Key
High(9)                    Low (0)
?Disordered
Alpha helix
Beta strand

Domain analysis 

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

RankAligned region

PDB 3mra chain A

3D model

Region: 7 - 18
Aligned: 12
Modelled: 12
Confidence: 25.8%
Identity: 67%
PDB header:membrane protein
Chain: A: PDB Molecule:nicotinic acetylcholine receptor;
PDBTitle: m3 transmembrane segment of alpha-subunit of nicotinic2 acetylcholine receptor from torpedo californica, nmr, 153 structures

Phyre2

PDB 3b8f chain B

3D model

Region: 19 - 25
Aligned: 7
Modelled: 7
Confidence: 14.1%
Identity: 43%
PDB header:hydrolase
Chain: B: PDB Molecule:putative blasticidin s deaminase;
PDBTitle: crystal structure of the cytidine deaminase from bacillus anthracis

Phyre2

PDB 3oj6 chain C

3D model

Region: 19 - 25
Aligned: 7
Modelled: 7
Confidence: 9.0%
Identity: 57%
PDB header:hydrolase
Chain: C: PDB Molecule:blasticidin-s deaminase;
PDBTitle: crystal structure of blasticidin s deaminase from coccidioides immitis

Phyre2

PDB 1r5t chain A

3D model

Region: 20 - 25
Aligned: 6
Modelled: 6
Confidence: 6.2%
Identity: 50%
Fold: Cytidine deaminase-like
Superfamily: Cytidine deaminase-like
Family: Cytidine deaminase

Phyre2

PDB 1mtx chain A

3D model

Region: 20 - 29
Aligned: 10
Modelled: 10
Confidence: 5.6%
Identity: 50%
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: Scorpion toxin-like
Family: Short-chain scorpion toxins

Phyre2

PDB 1q90 chain M

3D model

Region: 4 - 11
Aligned: 8
Modelled: 8
Confidence: 5.3%
Identity: 88%
Fold: Single transmembrane helix
Superfamily: PetM subunit of the cytochrome b6f complex
Family: PetM subunit of the cytochrome b6f complex

Phyre2

PDB 2z3g chain A domain 1

3D model

Region: 19 - 25
Aligned: 7
Modelled: 7
Confidence: 5.2%
Identity: 57%
Fold: Cytidine deaminase-like
Superfamily: Cytidine deaminase-like
Family: Cytidine deaminase

Phyre2
1

c3mraA_
2

c3b8fB_
3

c3oj6C_
4

d1r5ta_
5

d1mtxa_
6

d1q90m_
7

d2z3ga1



Detailed template information 

#
Template Alignment Coverage3D Model Confidence
% i.d. Template Information
1c3mraA_



25.8 67 PDB header:membrane protein
Chain: A: PDB Molecule:nicotinic acetylcholine receptor;
PDBTitle: m3 transmembrane segment of alpha-subunit of nicotinic2 acetylcholine receptor from torpedo californica, nmr, 153 structures
2c3b8fB_



14.1 43 PDB header:hydrolase
Chain: B: PDB Molecule:putative blasticidin s deaminase;
PDBTitle: crystal structure of the cytidine deaminase from bacillus anthracis
3c3oj6C_



9.0 57 PDB header:hydrolase
Chain: C: PDB Molecule:blasticidin-s deaminase;
PDBTitle: crystal structure of blasticidin s deaminase from coccidioides immitis
4d1r5ta_



6.2 50 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Cytidine deaminase
5d1mtxa_



5.6 50 Fold:Knottins (small inhibitors, toxins, lectins)
Superfamily:Scorpion toxin-like
Family:Short-chain scorpion toxins
6d1q90m_



5.3 88 Fold:Single transmembrane helix
Superfamily:PetM subunit of the cytochrome b6f complex
Family:PetM subunit of the cytochrome b6f complex
7d2z3ga1



5.2 57 Fold:Cytidine deaminase-like
Superfamily:Cytidine deaminase-like
Family:Cytidine deaminase

Binding site prediction 

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite



Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
 
© Structural Bioinformatics Group
Imperial College London
Lawrence Kelley, Benjamin Jefferys
Disclaimer
Terms and Conditions
Component software
Template detection: HHpred 1.51
Secondary structure prediction: Psi-pred 2.5
Disorder prediction: Disopred 2.4
Transmembrane prediction: Memsat_SVM
Multi-template modelling and ab initio: Poing 1.0